2. Gene
  3. HIVEP3 - HIVEP zinc finger 3 Gene

HIVEP3 - HIVEP zinc finger 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KRC; KBP1; SHN3; ZAS3; KBP-1; ZNF40C; Schnurri-3

Gene ID: 59269 | Gene type: protein coding

About HIVEP3

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:41,506,365-42,035,934 (from NCBI)

This gene has 7 transcripts (splice variants), 202 orthologues and 14 paralogues. Ubiquitous expression in skin (RPKM 2.3), brain (RPKM 1.1) and 24 other tissues.

Summary

This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]

HIVEP3 Products(2)

mRNA Protein Name
NM_001127714.3 NP_001121186.1 transcription factor HIVEP3 isoform b
NM_024503.5 NP_078779.2 transcription factor HIVEP3 isoform a

HIVEP3 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (207 - 231)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1769 - 1793)

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  • 2406 a.a.
Protein Preferred Names Protein Names

transcription factor HIVEP3

ZAS family, member 3

Related Diseases

Diseases Alias
Laurence-Moon Syndrome

LNMS

Laurence-Moon-Biedl Syndrome
Meckel Syndrome, Type 1

Meckel-Gruber Syndrome

Meckel Syndrome

Dysencephalia Splanchnocystica

Meckel Syndrome 1

MKS1

Mks

Gruber Syndrome

Meckel-Gruber Syndrome, Type 1

Mes

Dysencephalia Splachnocystica

Meckel Gruber Syndrome

Meckel Syndrome Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06189 HIVEP3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta HIVEP3 VGNC VGNC:96556
Felis catus HIVEP3 VGNC VGNC:96549
Rattus norvegicus HIVEP3 RGD RGD:1311252
Canis familiaris HIVEP3 VGNC VGNC:81689
Bos taurus HIVEP3 VGNC VGNC:96544
Mus musculus HIVEP3 MGD MGI:106589