2. Gene
  3. HAPLN2 - hyaluronan and proteoglycan link protein 2 Gene

HAPLN2 - hyaluronan and proteoglycan link protein 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BRAL1

Gene ID: 60484 | Gene type: protein coding

About HAPLN2

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:156,601,504-156,625,725 (from NCBI)

This gene has 5 transcripts (splice variants), 183 orthologues and 7 paralogues. Biased expression in brain (RPKM 7.0), prostate (RPKM 0.6) and 2 other tissues.

Summary

Predicted to enable hyaluronic acid binding activity. Predicted to be involved in central nervous system development and skeletal system development. Predicted to act upstream of or within establishment of blood-nerve barrier and extracellular matrix assembly. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

HAPLN2 Products(1)

mRNA Protein Name
NM_021817.3 NP_068589.1 hyaluronan and proteoglycan link protein 2 precursor

HAPLN2 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (44 - 136)

Xlink

Xlink: Extracellular link domain (147 - 241)

Xlink

Xlink: Extracellular link domain (255 - 337)

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  • 340 a.a.
Protein Preferred Names Protein Names

hyaluronan and proteoglycan link protein 2

brain link protein-1

Related Diseases

Diseases Alias
Polycystic Echinococcosis

Human Polycystic Hydatid Disease

Neotropical Echinococcosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06002 HAPLN2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta HAPLN2 VGNC VGNC:106378
Mus musculus HAPLN2 MGD MGI:2137300
Rattus norvegicus HAPLN2 RGD RGD:621854
Canis familiaris HAPLN2 VGNC VGNC:53491
Bos taurus HAPLN2 VGNC VGNC:29750
Felis catus HAPLN2 VGNC VGNC:62751