2. Gene
  3. EEFSEC - eukaryotic elongation factor, selenocysteine-tRNA specific Gene

EEFSEC - eukaryotic elongation factor, selenocysteine-tRNA specific Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SELB; EFSEC

Gene ID: 60678 | Gene type: protein coding

About EEFSEC

Cytogenetic location: 3q21.3 Genomic coordinates (GRCh38): 3:128,153,481-128,426,223 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 197 orthologues and 18 paralogues. Ubiquitous expression in testis (RPKM 3.1), kidney (RPKM 2.8) and 25 other tissues.

Summary

Predicted to enable translation elongation factor activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]

EEFSEC Products(1)

mRNA Protein Name
NM_021937.5 NP_068756.2 selenocysteine-specific elongation factor

EEFSEC Protein Structure

GTP_EFTU

GTP_EFTU: Elongation factor Tu GTP binding domain (7 - 212)

GTP_EFTU_D2

GTP_EFTU_D2: Elongation factor Tu domain 2 (238 - 291)

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  • 596 a.a.
Protein Preferred Names Protein Names

selenocysteine-specific elongation factor

elongation factor for selenoprotein translation

Related Diseases

Diseases Alias
Keshan Disease

Caused By Deficiency Of Selenium In The Diet

Enlarged Heart And Poor Heart Function
Colorado Tick Fever

Mountain Tick Fever

Tick Fever, American Mountain

American Mountain Fever

Colorado Tick Encephalitis

Colorado Tick-Borne Disease

Mountain Fever

American Mountain Tick Fever

Colorado Tick-Borne Fever

Colorado Tick Fever Virus

Non-Exanthematous Tick Fever
Rigid Spine Muscular Dystrophy 1

Rigid Spine Syndrome

RSMD1

Rss

Mdrs1

Eichsfeld Type Congenital Muscular Dystrophy

Desmin-Related Myopathy With Mallory Bodies

Classic Multiminicore Myopathy

Sepn1-Related Myopathy

Multicore Myopathy, Severe Classic Form

Minicore Myopathy, Severe Classic Form

Multiminicore Disease, Severe Classic Form

Muscular Dystrophy, Rigid Spine, 1

Classic Mmd

Classic Multiminicore Disease

Congenital Merosin-Positive Muscular Dystrophy With Early Spine Rigidity

Desmin-Related Myopathy With Mallory Body-Like Inclusions

Early-Onset Desmin-Related Myopathy

Myopathy, Sepn1-Related

Muscular Dystrophy, Congenital, Merosin-Positive, With Early Spine Rigidity

Muscular Dystrophy, Congenital, Eichsfeld Type

Severe Classic Form Minicore Myopathy

Severe Classic Form Multicore Myopathy

Severe Classic Form Multiminicore Disease

Desmin-Related Myopathies With Mallory Bodies

Muscular Dystrophy, Congenital, Merosin Positive With Early Spine Rigidity

Rigid Spine Muscular Dystrophy-1

Rigid Spine Congenital Muscular Dystrophy

Congenital Muscular Dystrophy Eichsfeld Type

Congenital Muscular Dystrophy Merosin-Positive With Early Spine Rigidity

Minicore Myopathy Severe Classic Form

Multicore Myopathy Severe Classic Form

Multiminicore Disease Severe Classic Form

Dystrophy, Muscular, Rigid Spine, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04182 EEFSEC Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EEFSEC RGD RGD:1560552
Macaca mulatta EEFSEC VGNC VGNC:72097
Bos taurus EEFSEC VGNC VGNC:28337
Felis catus EEFSEC VGNC VGNC:61735
Mus musculus EEFSEC MGD MGI:2137092
Canis familiaris EEFSEC VGNC VGNC:40211