CLEC11A - C-type lectin domain containing 11A Gene

Homo sapiens

Also known as P47; SCGF; LSLCL; CLECSF3

Gene ID: 6320 | Gene type: protein coding

About CLEC11A

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:50,723,364-50,725,708 (from NCBI)

This gene has 2 transcripts (splice variants), 174 orthologues and 2 paralogues. Broad expression in bone marrow (RPKM 36.6), endometrium (RPKM 6.5) and 15 other tissues.

Summary

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]

CLEC11A Products(1)

mRNA	Protein	Name
NM_002975.3	NP_002966.1	C-type lectin domain family 11 member A precursor

CLEC11A Protein Structure

Lectin_C

0
100
200
300
323 a.a.

Protein Preferred Names

Protein Names

C-type lectin domain family 11 member A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 3

Related Diseases

Diseases

Alias

Benign Mastocytoma

Chronic Granulomatous Disease

Cgd	Granulomatous Disease, Chronic
Autosomal Recessive Chronic Granulomatous Disease	X-Linked Chronic Granulomatous Disease
Bridges-Good Syndrome	Congenital Dysphagocytosis
Quie Syndrome	Chronic Septic Granulomatosis
Chronic Granulomatous Disorder	Granulomatous Disease Chronic
Granulomatous Disease, Chronic, X-Linked

Piebald Trait

Piebaldism	PBT
Partial Albinism	Albinoidism, Oculocutaneous, Autosomal Dominant

Esophageal Lipoma

Lipoma Of Esophagus

Solitary Mastocytoma Of The Skin

Cutaneous Solitary Mastocytoma	Skin Mastocytoma
Solitary Mastocytoma	Solitary Mastocytoma Of Skin
Mastocytoma, Skin

Aggressive Systemic Mastocytosis

Asm	Lymphadenopathic Mastocytosis With Eosinophilia

Osteopetrosis

Marble Bone Disease	Albers-Schonberg Disease
Osteopetroses	Marble Bones
Osteopetrosis And Related Disorders	Congenital Osteopetrosis
Marble Bone	Albers-Schoenberg Disease
Albers-Schonberg Osteopetrosis	Osteosclerosis Fragilis
Ivory Bones

Gastrointestinal Stromal Tumor

GIST	Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Sarcoma	Gastrointestinal Stromal Tumor, Familial
Gant	Gastrointestinal Stromal Tumour
Stromal Tumor Of Gastrointestinal Tract	Stromal Tumour Of Gastrointestinal Tract
Gastrointestinal Stromal Neoplasm	Paraganglioma And Gastric Stromal Sarcoma
Plexosarcoma

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic	Acute Myeloblastic Leukemia Type 3
Aml M3	APL
Leukemia, Acute Promyelocytic, Somatic	Aml With T(15
17)(Q22	Q12)
(Pml/Raralpha) And Variants	Apml
Acute Myeloblastic Leukemia 3	Acute Myeloid Leukemia With T(15
17)(Q22	Q12)
(Pml/Raralpha) And Variants	Acute Myeloblastic Leukaemia Type 3
Acute Myeloid Leukaemia M3	Acute Myeloid Leukemia M3
Acute Promyelocytic Leukaemia	M3 Anll
Myeloid Leukemia, Acute, M3	Leukemia Promyelocytic Acute
Leukemia, Promyelocytic, Acute	Leukemia, Acute, Promyelocytic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02780	CLEC11A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CLEC11A	RGD	RGD:3627
Mus musculus	CLEC11A	MGD	MGI:1298219
Macaca mulatta	CLEC11A	VGNC	VGNC:71167
Bos taurus	CLEC11A	VGNC	VGNC:27422
Canis familiaris	CLEC11A	VGNC	VGNC:49644

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