2. Gene
  3. Gpr88 - G-protein coupled receptor 88 Gene

Gpr88 - G-protein coupled receptor 88 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Strg

Gene ID: 64378 | Gene type: protein coding

About Gpr88

Chromosome 3: 116,043,303-116,047,152 reverse strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 147 orthologues, 55 paralogues and is associated with 31 phenotypes. Biased expression in cortex adult (RPKM 16.3), CNS E18 (RPKM 8.2) and 9 other tissues.

Summary

Enables cytoskeletal motor activity. Involved in motor learning. Acts upstream of or within locomotory behavior; neuromuscular process controlling balance; and neuronal action potential. Predicted to be located in several cellular components, including cilium; nucleus; and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; ear; genitourinary system; and skeleton. Orthologous to human GPR88 (G protein-coupled receptor 88). [provided by Alliance of Genome Resources, Apr 2022]

Gpr88 Products(4)

mRNA Protein Name
NM_001411424.1 NP_001398353.1 probable G-protein coupled receptor 88
NM_001411426.1 NP_001398355.1 probable G-protein coupled receptor 88
NM_022427.3 NP_071872.1 probable G-protein coupled receptor 88
NM_001411425.1 NP_001398354.1 probable G-protein coupled receptor 88

Gpr88 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (32 - 346)

7tm_GPCRs

7tm_GPCRs: cd14964 (33 - 57)

7tm_GPCRs

7tm_GPCRs: cd14964 (66 - 88)

7tm_GPCRs

7tm_GPCRs: cd14964 (113 - 135)

7tm_GPCRs

7tm_GPCRs: cd14964 (159 - 175)

7tm_GPCRs

7tm_GPCRs: cd14964 (189 - 212)

7tm_GPCRs

7tm_GPCRs: cd14964 (282 - 304)

7tm_GPCRs

7tm_GPCRs: cd14964 (314 - 339)

  • 0
  • 100
  • 200
  • 300
  • 384 a.a.
Protein Preferred Names Protein Names

probable G-protein coupled receptor 88

striatum-specific G-protein coupled receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100013A1 (1R,2R)-2-PCCA hydrochloride 98.08% Unkown
HY-100013C 2-PCCA hydrochloride 99.63% Unkown
HY-112612A RTI-13951-33 hydrochloride 98.56% Unkown
HY-156771 GPR88-IN-1 Inhibitor 99.54% Unkown
HY-112612 RTI-13951-33 / Unkown
HY-156772 GPR88 agonist 2 Agonist 99.57% Unkown
HY-163096 GPR88 agonist 3 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr88 NCBI NCBI:54112