2. Gene
  3. SPANXC - SPANX family member C Gene

SPANXC - SPANX family member C Gene

  • Gene
  • Protein
  • Disease
  • Agent
Homo sapiens

Also known as CTp11; CT11.3; SPANXE; SPANX-C; SPANX-E

Gene ID: 64663 | Gene type: protein coding

About SPANXC

Cytogenetic location: Xq27.2 Genomic coordinates (GRCh38): X:141,241,463-141,242,517 (from NCBI)

This gene has 1 transcript (splice variant), 3 orthologues and 4 paralogues. Restricted expression toward testis (RPKM 12.8).

Summary

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of Cancer/testis antigens and represents a potential target for Cancer Immunotherapy. [provided by RefSeq, Jul 2008]

SPANXC Products(1)

mRNA Protein Name
NM_022661.4 NP_073152.2 sperm protein associated with the nucleus on the X chromosome C

SPANXC Protein Structure

SPAN-X

SPAN-X: Sperm protein associated with nucleus, mapped to X chromosome (1 - 96)

  • 0
  • 97 a.a.
Protein Preferred Names Protein Names

sperm protein associated with the nucleus on the X chromosome C

Nuclear-associated protein SPAN-Xe

Related Diseases

Diseases Alias
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13629 SPANXC Human Pre-designed siRNA Set A / Unkown