PRCD - photoreceptor disc component Gene

Homo sapiens

Also known as RP36

Gene ID: 768206 | Gene type: protein coding

About PRCD

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:76,527,586-76,553,580 (from NCBI)

This gene has 13 transcripts (splice variants), 66 orthologues and is associated with 3 phenotypes. Ubiquitous expression in fat (RPKM 1.8), adrenal (RPKM 1.0) and 23 other tissues.

Summary

This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

PRCD Products(1)

mRNA	Protein	Name
NM_001077620.3	NP_001071088.1	photoreceptor disk component PRCD precursor

PRCD Protein Structure

Rod_cone_degen

0
54 a.a.

Protein Preferred Names

Protein Names

photoreceptor disk component PRCD

progressive rod-cone degeneration protein

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 36

RP36	Retinitis Pigmentosa-36
Retinitis Pigmentosa, Type 36

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Ichthyosis, Congenital, Autosomal Recessive 10

Autosomal Recessive Congenital Ichthyosis 10	ARCI10
Ichthyosis, Congenital, Autosomal Recessive, Type 10

Cone-Rod Dystrophy 1

CORD1	Crd1
Cone-Rod Retinal Dystrophy-1	Retinitis Pigmentosa 1

Macular Degeneration, X-Linked Atrophic

X-Linked Atrophic Macular Degeneration	Macular Degeneration, X-Linked, Atrophic
MDXLA	Degeneration, Macular, X-Linked Atrophic

Retinitis Pigmentosa 17

RP17	Retinitis Pigmentosa-17
Retinitis Pigmentosa, Type 17

Corneal Dystrophy, Posterior Amorphous

Posterior Amorphous Corneal Dystrophy	PACD
Chromosome 12q21.33 Deletion Syndrome	Posterior Amorphous Stromal Dystrophy

Ceroid Lipofuscinosis, Neuronal, 5

Neuronal Ceroid Lipofuscinosis 5	CLN5
Cln5 Disease	Finnish Variant Late Infantile Neuronal Ceroid Lipofuscinosis
Vlincl	Ceroid Lipofuscinosis, Neuronal, 5, Variable Age At Onset
Neuronal Ceroid Lipofuscinosis 5 Variable Age Of Onset	Cln5 Disease, Adult
Cln5 Disease, Juvenile	Cln5 Disease, Late Infantile
Neuronal Ceroid Lipofuscinosis Finnish Variant	Finnish Vlincl
Jansky-Bielschowsky Disease	Late-Infantile Neuronal Ceroid Lipofuscinosis
Neuronal Ceroid Lipofuscinosis, Late-Infantile	Finnish
Neuronal Ceroid Lipofuscinosis 5 With Variable Age At Onset	Lipofuscinosis, Ceroid, Neuronal, Type 5
Late-Infantile Neuronal Ceroid Lipfuscinosis	Ceroid Lipofuscinosis, Neuronal, 6

Retinal Degeneration

Degeneration Of Retina

Chronic Interstitial Cystitis

Bestrophinopathy, Autosomal Recessive

Bestrophinopathy	Autosomal Recessive Bestrophinopathy
ARB	Bestrophinopathies
Retinopathy, Burgess-Black Type	Retinopathy Burgess-Black Type

Late-Onset Retinal Degeneration

LORD	Retinal Degeneration, Late-Onset, Autosomal Dominant
Autosomal Dominant Late-Onset Retinal Degeneration	Pigmentary Retinopathy
Retinal Degeneration, Late-Onset	Retinitis Pigmentosa

Sveinsson Chorioretinal Atrophy

SCRA	Atrophia Areata
Helicoid Peripapillary Chorioretinal Degeneration	Hpcd
Aa	Peripapillary Chorioretinal Degeneration, Icelandic Type
Helicoidal Peripapillary Chorioretinal Degeneration	Atrophy, Chorioretinal, Sveinsson

Achromatopsia

Achm	Rod Monochromatism
Total Color Blindness	Rod Monochromacy
Monochromatism	Achromatism
Complete Or Incomplete Color Blindness	Pingelapese Blindness
Achromatopsia 1	Achromatopsia 2
Achromatopsia 3

Eye Degenerative Disease

Leber Plus Disease

Leber Congenital Amaurosis	Lca
Leber'S Amaurosis	Leber'S Disease
Amaurosis Congenita Of Leber	Amaurosis Congenita Of Leber, Type 1
Lhon Plus Disease	Congenital Absence Of The Rods And Cones
Congenital Retinal Blindness	Crb
Congenital Amaurosis Of Retinal Origin	Leber'S Congenital Amaurosis
Leber Congenital Amaurosis 1	Leber'S Congenital Tapetoretinal Degeneration
Leber'S Congenital Tapetoretinal Dysplasia	Lca1
Leber Congenital Amaurosis Type 1	Retinal Blindness, Congenital
Amaurosis, Leber Congenital	Dysgenesis Neuroepithelialis Retinae
Hereditary Epithelial Dysplasia Of Retina	Hereditary Retinal Aplasia
Heredoretinopathia Congenitalis	Leber Abiotrophy
Leber Congenital Tapetoretinal Degeneration	Lebers Congenital Amaurosis
Optic Atrophy, Hereditary, Leber

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11057	PRCD Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PRCD	VGNC	VGNC:33286
Rattus norvegicus	PRCD	RGD	RGD:6488422
Canis familiaris	PRCD	VGNC	VGNC:44942
Mus musculus	PRCD	MGD	MGI:3649529
Macaca mulatta	PRCD	VGNC	VGNC:104643
Felis catus	PRCD	VGNC	VGNC:99324