Lpar4 - lysophosphatidic acid receptor 4 Gene

Mus musculus

Also known as LPA4; p2y9; Gpr23; 5730485F04Rik

Gene ID: 78134 | Gene type: protein coding

About Lpar4

Chromosome X: 105,964,231-105,977,506 forward strand.GRCm39:CM001013.3

This gene has 1 transcript (splice variant), 174 orthologues, 16 paralogues and is associated with 22 phenotypes. Biased expression in limb E14.5 (RPKM 7.9), CNS E11.5 (RPKM 2.4) and 1 other tissues.

Summary

Enables lysophosphatidic acid binding activity and lysophosphatidic acid receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Predicted to act upstream of or within signal transduction. Located in plasma membrane. Is expressed in several structures, including branchial arch; future brain; limb; nose; and skeleton. Orthologous to human LPAR4 (lysophosphatidic acid receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Lpar4 Products(1)

mRNA	Protein	Name
NM_175271.4	NP_780480.2	lysophosphatidic acid receptor 4

Lpar4 Protein Structure

7tmA_LPAR4

0
100
200
300
370 a.a.

Protein Preferred Names

Protein Names

lysophosphatidic acid receptor 4

G protein-coupled receptor 23	LPA receptor 4
LPA-4	P2Y purinoceptor 9
purinergic receptor 9

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS07755	LPAR4 Human Pre-designed siRNA Set A	/	Unkown
HY-RS07756	Lpar4 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS07757	Lpar4 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lpar4	NCBI	NCBI:2846

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