1. Gene
  2. RNF39 - ring finger protein 39 Gene

RNF39 - ring finger protein 39 Gene

Homo sapiens

Also known as HZF; HZFW; LIRF; FAP216

Gene ID: 80352 | Gene type: protein coding

About RNF39

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:30,070,270-30,075,769 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 83 orthologues and 80 paralogues. Ubiquitous expression in small intestine (RPKM 5.5), duodenum (RPKM 5.3) and 25 other tissues.

Summary

This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNF39 Products(2)

mRNA Protein Name
NM_025236.4 NP_079512.3 RING finger protein 39 isoform 1
NM_170769.3 NP_739575.3 RING finger protein 39 isoform 2

RNF39 Protein Structure

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (88 - 134)

PRY

PRY: SPRY-associated domain (230 - 279)

SPRY

SPRY: SPRY domain (282 - 405)

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  • 200
  • 300
  • 420 a.a.
Protein Preferred Names Protein Names

RING finger protein 39

LTP (long-term potentiation) induced RING finger protein

Related Diseases

Diseases Alias
Psoriasis 10

PSORS10

Psoriasis Susceptibility 10

Psoriasis 10, Susceptibility To

Behcet Syndrome

Behcet Disease

Behcet'S Syndrome

Behcet'S Disease

Behçet Disease

Bd

Adamantiades-Behcet Disease

Triple Symptom Complex

Behçet'S Disease

Behet'S Syndrome

Bd Syndrome

Behçet Syndrome

Behçet'S Syndrome

Behcet Triple Symptom Complex

Malignant Aphthosis

Old Silk Route Disease

Adamantiades-Behçet Disease

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus RNF39 VGNC VGNC:106899
Macaca mulatta RNF39 VGNC VGNC:83458
Rattus norvegicus RNF39 RGD RGD:628854
Canis familiaris RNF39 VGNC VGNC:54988
Mus musculus RNF39 MGD MGI:2156378