SESN2 - sestrin 2 Gene

Homo sapiens

Also known as HI95; SES2; SEST2

Gene ID: 83667 | Gene type: protein coding

About SESN2

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:28,259,518-28,282,491 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 189 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 15.0), kidney (RPKM 10.3) and 24 other tissues.

Summary

This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions. [provided by RefSeq, Jul 2008]

SESN2 Products(1)

mRNA	Protein	Name
NM_031459.5	NP_113647.1	sestrin-2

SESN2 Protein Structure

PA26

0
100
200
300
400
480 a.a.

Protein Preferred Names

Protein Names

sestrin-2

hypoxia induced gene 95

Related Diseases

Diseases

Alias

Pulmonary Emphysema

Nodular Ganglioneuroblastoma

Ganglioneuroblastoma, Nodular

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12735	SESN2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SESN2	VGNC	VGNC:77286
Bos taurus	SESN2	VGNC	VGNC:34489
Rattus norvegicus	SESN2	RGD	RGD:1566319
Canis familiaris	SESN2	VGNC	VGNC:46048
Felis catus	SESN2	VGNC	VGNC:65035
Mus musculus	SESN2	MGD	MGI:2651874

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