GPR61 - G protein-coupled receptor 61 Gene

Homo sapiens

Also known as BALGR; GPCR3

Gene ID: 83873 | Gene type: protein coding

About GPR61

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:109,539,872-109,547,260 (from NCBI)

This gene has 7 transcripts (splice variants), 247 orthologues and 3 paralogues. Biased expression in brain (RPKM 1.2), thyroid (RPKM 0.5) and 3 other tissues.

Summary

This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008]

GPR61 Products(2)

mRNA	Protein	Name
NM_001393907.1	NP_001380836.1	G-protein coupled receptor 61
NM_031936.6	NP_114142.3	G-protein coupled receptor 61

GPR61 Protein Structure

7tm_1

0
100
200
300
400
451 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor 61

biogenic amine receptor-like G-protein coupled receptor

Related Diseases

Diseases

Alias

Olfactory Groove Meningioma

Meningioma Of The Olfactory Groove

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-156354	GPR61 Inverse agonist 1		≥98.0%	Unkown
HY-RS05727	GPR61 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	GPR61	VGNC	VGNC:54028
Macaca mulatta	GPR61	VGNC	VGNC:72933
Felis catus	GPR61	VGNC	VGNC:62692
Bos taurus	GPR61	VGNC	VGNC:29593
Rattus norvegicus	GPR61	RGD	RGD:1310176
Mus musculus	GPR61	MGD	MGI:2441719

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