2. Gene
  3. Prkci - protein kinase C, iota Gene

Prkci - protein kinase C, iota Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pkcl

Gene ID: 84006 | Gene type: protein coding

About Prkci

Primary_assembly 2: 112,321,929-112,382,352 reverse strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 228 orthologues, 9 paralogues and is associated with 8 phenotypes. Biased expression in Lung (RPKM 259.4), Kidney (RPKM 161.9) and 9 other tissues.

Summary

Predicted to enable phospholipid binding activity and protein kinase C activity. Involved in several processes, including Golgi vesicle budding; cellular response to Insulin stimulus; and response to interleukin-1. Located in cell leading edge; cytosol; and plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Colocalizes with bicellular tight junction. Orthologous to human PRKCI (protein kinase C iota). [provided by Alliance of Genome Resources, Apr 2022]

Prkci Products(1)

mRNA Protein Name
NM_032059.1 NP_114448.1 protein kinase C iota type

Prkci Protein Structure

PB1_aPKC

PB1_aPKC: cd06404 (25 - 107)

C1_aPKC

C1_aPKC: cd20794 (138 - 192)

STKc_aPKC_iota

STKc_aPKC_iota: cd05618 (232 - 595)

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  • 596 a.a.
Protein Preferred Names Protein Names

protein kinase C iota type

aPKC-lambda/iota

atypical protein kinase C-lambda/iota

nPKC-iota

protein kinase C, lambda

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11134 PRKCI Human Pre-designed siRNA Set A / Unkown
HY-RS11135 Prkci Mouse Pre-designed siRNA Set A / Unkown
HY-RS11136 Prkci Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkci NCBI NCBI:5584