2. Gene
  3. CNTNAP4 - contactin associated protein family member 4 Gene

CNTNAP4 - contactin associated protein family member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CASPR4

Gene ID: 85445 | Gene type: protein coding

About CNTNAP4

Cytogenetic location: 16q23.1 Genomic coordinates (GRCh38): 16:76,277,401-76,560,757 (from NCBI)

This gene has 9 transcripts (splice variants), 122 orthologues and 35 paralogues. Biased expression in brain (RPKM 7.4) and adrenal (RPKM 0.3).

Summary

This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016]

CNTNAP4 Products(11)

mRNA Protein Name
NM_001322178.2 NP_001309107.1 contactin-associated protein-like 4 isoform 3 precursor
NM_001322179.2 NP_001309108.1 contactin-associated protein-like 4 isoform 4 precursor
NM_001322180.2 NP_001309109.1 contactin-associated protein-like 4 isoform 5
NM_001322181.2 NP_001309110.1 contactin-associated protein-like 4 isoform 6 precursor
NM_001322187.2 NP_001309116.1 contactin-associated protein-like 4 isoform 7
NM_001322188.2 NP_001309117.1 contactin-associated protein-like 4 isoform 8 precursor
NM_001322189.2 NP_001309118.1 contactin-associated protein-like 4 isoform 9
NM_001322190.2 NP_001309119.1 contactin-associated protein-like 4 isoform 10 precursor
NM_001322191.2 NP_001309120.1 contactin-associated protein-like 4 isoform 11
NM_033401.5 NP_207837.2 contactin-associated protein-like 4 isoform 1 precursor
NM_138994.5 NP_620481.2 contactin-associated protein-like 4 isoform 2

CNTNAP4 Protein Structure

F5_F8_type_C

F5_F8_type_C: F5/8 type C domain (48 - 177)

Laminin_G_2

Laminin_G_2: Laminin G domain (215 - 343)

Laminin_G_2

Laminin_G_2: Laminin G domain (401 - 526)

Laminin_G_2

Laminin_G_2: Laminin G domain (824 - 942)

Laminin_G_2

Laminin_G_2: Laminin G domain (1049 - 1177)

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  • 1311 a.a.
Protein Preferred Names Protein Names

contactin-associated protein-like 4

cell recognition molecule Caspr4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02936 CNTNAP4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CNTNAP4 VGNC VGNC:27541
Felis catus CNTNAP4 VGNC VGNC:61038
Rattus norvegicus CNTNAP4 RGD RGD:1306459
Macaca mulatta CNTNAP4 VGNC VGNC:71209
Canis familiaris CNTNAP4 VGNC VGNC:39439
Mus musculus CNTNAP4 MGD MGI:2183572