2. Gene
  3. EIF3J - eukaryotic translation initiation factor 3 subunit J Gene

EIF3J - eukaryotic translation initiation factor 3 subunit J Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as EIF3S1; eIF3-p35; eIF3-alpha

Gene ID: 8669 | Gene type: protein coding

About EIF3J

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:44,537,147-44,562,803 (from NCBI)

This gene has 7 transcripts (splice variants) and 248 orthologues. Ubiquitous expression in appendix (RPKM 31.0), brain (RPKM 29.6) and 25 other tissues.

Summary

This gene encodes a core subunit of the eukaryotic initiation factor 3 complex, which participates in the initiation of translation by aiding in the recruitment of protein and mRNA components to the 40S ribosome. There are pseudogenes for this gene on chromosomes 1, 3, and 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

EIF3J Products(3)

mRNA Protein Name
NM_001284335.2 NP_001271264.1 eukaryotic translation initiation factor 3 subunit J isoform 2
NM_001284336.2 NP_001271265.1 eukaryotic translation initiation factor 3 subunit J isoform 3
NM_003758.4 NP_003749.2 eukaryotic translation initiation factor 3 subunit J isoform 1

EIF3J Protein Structure

eIF3_subunit

eIF3_subunit: Translation initiation factor eIF3 subunit (12 - 258)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 3 subunit J

eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04266 EIF3J Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus EIF3J VGNC VGNC:80979
Mus musculus EIF3J MGD MGI:1925905
Canis familiaris EIF3J VGNC VGNC:40276
Bos taurus EIF3J VGNC VGNC:28400
Macaca mulatta EIF3J VGNC VGNC:72188
Rattus norvegicus EIF3J RGD RGD:1593338