1. Gene
  2. CBR3 - carbonyl reductase 3 Gene

CBR3 - carbonyl reductase 3 Gene

Homo sapiens

Also known as hCBR3; SDR21C2; HEL-S-25

Gene ID: 874 | Gene type: protein coding

About CBR3

Cytogenetic location: 21q22.12 Genomic coordinates (GRCh38): 21:36,135,079-36,146,562 (from NCBI)

This gene has 1 transcript (splice variant), 503 orthologues and 13 paralogues. Ubiquitous expression in esophagus (RPKM 6.1), skin (RPKM 5.7) and 22 other tissues.

Summary

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The Enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]

CBR3 Products(1)

mRNA Protein Name
NM_001236.4 NP_001227.1 carbonyl reductase [NADPH] 3

CBR3 Protein Structure

adh_short

adh_short: short chain dehydrogenase (7 - 147)

  • 0
  • 100
  • 200
  • 277 a.a.
Protein Preferred Names Protein Names

carbonyl reductase [NADPH] 3

NADPH-dependent carbonyl reductase 3

Recombinant CBR3 Proteins

Cat. No. Product Name Accession Purity
HY-P75605 CBR3 Protein, Human (His) O75828 (M1-W277) ≥95%

Orthologs Information

Species Symbol Source ID
Mus musculus CBR3 MGD MGI:1309992
Bos taurus CBR3 VGNC VGNC:53516
Rattus norvegicus CBR3 RGD RGD:1309728
Canis familiaris CBR3 VGNC VGNC:38764
Felis catus CBR3 VGNC VGNC:102611
Others CBR3 NCBI