FBP2 - fructose-bisphosphatase 2 Gene

Homo sapiens

Also known as CORLK

Gene ID: 8789 | Gene type: protein coding

About FBP2

Cytogenetic location: 9q22.32 Genomic coordinates (GRCh38): 9:94,558,720-94,593,824 (from NCBI)

This gene has 1 transcript (splice variant), 198 orthologues, 1 paralogue and is associated with 1 phenotype. Biased expression in stomach (RPKM 15.5), esophagus (RPKM 4.0) and 3 other tissues.

Summary

This gene encodes a gluconeogenesis regulatory Enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. [provided by RefSeq, Jul 2008]

FBP2 Products(1)

mRNA	Protein	Name
NM_003837.4	NP_003828.2	fructose-1,6-bisphosphatase isozyme 2

FBP2 Protein Structure

FBPase

0
100
200
300
339 a.a.

Protein Preferred Names

Protein Names

fructose-1,6-bisphosphatase isozyme 2

D-fructose-1,6-bisphosphate 1-phosphohydrolase 2

Related Diseases

Diseases

Alias

Leukodystrophy, Childhood-Onset, Remitting

CORLK

Fructose-1,6-Bisphosphatase Deficiency

Fructose-1,6-Diphosphatase Deficiency	Baker-Winegrad Disease
FBP1D	Fbpase Deficiency
Fructose 1,6 Diphosphatase Deficiency	Fructose 1 Phosphate Aldolase Deficiency
Fbp1 Deficiency	Hereditary Fructose Intolerance Syndrome

Glycogen Storage Disease

Glycogenosis	Glycogenoses
Gsd	Storage Disease, Glycogen
Gsd - [Glycogen Storage Disease]	Glycogen Thesaurismosis
Diffuse Glycogenosis	Generalised Glycogen Storage Disease
Generalised Glycogenosis	Generalised Glycogen Storage Disease Of Infants
Glycogen Synthase Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04780	FBP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	FBP2	VGNC	VGNC:62173
Rattus norvegicus	FBP2	RGD	RGD:620930
Macaca mulatta	FBP2	VGNC	VGNC:72626
Bos taurus	FBP2	VGNC	VGNC:28888
Canis familiaris	FBP2	VGNC	VGNC:49894
Mus musculus	FBP2	MGD	MGI:95491
Others	FBP2	NCBI

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