1. Gene
  2. FATE1 - fetal and adult testis expressed 1 Gene

FATE1 - fetal and adult testis expressed 1 Gene

Homo sapiens

Also known as CT43; FATE

Gene ID: 89885 | Gene type: protein coding

About FATE1

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:151,716,035-151,723,194 (from NCBI)

This gene has 2 transcripts (splice variants) and 77 orthologues. Restricted expression toward testis (RPKM 120.2).

Summary

This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq, Jan 2010]

FATE1 Products(1)

mRNA Protein Name
NM_033085.3 NP_149076.1 fetal and adult testis-expressed transcript protein

FATE1 Protein Structure

Miff

Miff: Mitochondrial and peroxisomal fission factor Mff (29 - 182)

  • 0
  • 100
  • 183 a.a.
Protein Preferred Names Protein Names

fetal and adult testis-expressed transcript protein

BJ-HCC-2 antigen

Related Diseases

Diseases Alias
Martin-Probst Syndrome

Deafness-Intellectual Disability, Martin-Probst Type Syndrome

Martin-Probst Deafness-Mental Retardation Syndrome

Mental Retardation, X-Linked, Syndromic, Martin-Probst Type

MRXSMP

Deafness-Intellectual Disability Syndrome, Martin-Probst Type

Hearing Loss-Intellectual Disability Syndrome, Martin-Probst Type

X-Linked Deafness-Intellectual Disability Syndrome Syndrome

X-Linked Hearing Loss-Intellectual Disability Syndrome Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus FATE1 VGNC VGNC:28878
Felis catus FATE1 VGNC VGNC:62160
Mus musculus FATE1 MGD MGI:1925155
Canis familiaris FATE1 VGNC VGNC:40746