SEMA5A - semaphorin 5A Gene

Homo sapiens

Also known as semF; SEMAF

Gene ID: 9037 | Gene type: protein coding

About SEMA5A

Cytogenetic location: 5p15.31 Genomic coordinates (GRCh38): 5:9,035,033-9,546,075 (from NCBI)

This gene has 5 transcripts (splice variants), 206 orthologues, 19 paralogues and is associated with 1 phenotype. Broad expression in lung (RPKM 6.9), kidney (RPKM 6.5) and 24 other tissues.

Summary

This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.[provided by RefSeq, Jan 2010]

SEMA5A Products(1)

mRNA	Protein	Name
NM_003966.3	NP_003957.2	semaphorin-5A precursor

SEMA5A Protein Structure

Sema

PSI

TSP_1

0
200
400
600
800
1000
1074 a.a.

Protein Preferred Names

Protein Names

semaphorin-5A

sema F

Recombinant SEMA5A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70496	Semaphorin-5A/SEMA5A Protein, Human (HEK293, His)	Q13591 (E23-T765)	≥95%
HY-P74560	Semaphorin-5A/SEMA5A Protein, Human (HEK293, Fc)	Q13591 (M1-T765)	≥95%

Related Diseases

Diseases

Alias

Cri-Du-Chat Syndrome

5p Deletion Syndrome	5p Partial Monosomy Syndrome
Monosomy 5p	Cat Cry Syndrome
Chromosome 5p Deletion Syndrome	Cri Du Chat Syndrome
5p- Syndrome	5p Minus Syndrome
Chromosome 5p- Syndrome	Chromosome 5 Short Arm Deletion Syndrome
Chromosome 5p Deletion	Deletion 5p
Cri Du Chat	5p Partial Deletion Syndrome
Partial Deletion Of Short Arm Of Chromosome 5 Syndrome

Glioma

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Autism Spectrum Disorder

Asd	Autism Spectrum Disorders
Autistic Continuum	Pervasive Developmental Disorder
Pervasive Development Disorder	Autistic Behavior
Autistic Disorder	Autistic
Autistic Disorder Of Childhood Onset	Infantile Autism
Childhood Autism	Kanner Syndrome
Pervasive Developmental Delay Nos	Pervasive Developmental Disorder, Not Otherwise Specified

Kallmann Syndrome

Hypogonadism With Anosmia	Kallman'S Syndrome
Anosmic Hypogonadism	Anosmic Idiopathic Hypogonadotropic Hypogonadism
Hypogonadotropic Hypogonadism And Anosmia	Hypogonadotropic Hypogonadism-Anosmia Syndrome
Olfacto-Genital Pathological Sequence	Familial Hypogonadism With Anosmia
Kallman Syndrome	Dysplasia Olfactogenitalis Of De Morsier
Kallmann'S Syndrome	Congenital Hypogonadotropic Hypogonadism With Anosmia

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12663	SEMA5A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SEMA5A	MGD	MGI:107556
Rattus norvegicus	SEMA5A	RGD	RGD:1308650
Bos taurus	SEMA5A	VGNC	VGNC:34439
Canis familiaris	SEMA5A	VGNC	VGNC:45999
Macaca mulatta	SEMA5A	VGNC	VGNC:77169
Felis catus	SEMA5A	VGNC	VGNC:64997
Others	SEMA5A	NCBI

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