ITM2A - integral membrane protein 2A Gene

Homo sapiens

Also known as E25A; BRICD2A

Gene ID: 9452 | Gene type: protein coding

About ITM2A

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:79,360,384-79,367,334 (from NCBI)

This gene has 6 transcripts (splice variants), 174 orthologues, 2 paralogues and is associated with 1 phenotype. Ubiquitous expression in ovary (RPKM 64.9), thyroid (RPKM 48.1) and 23 other tissues.

Summary

This gene encodes a type II membrane protein that belongs to the ITM2 family. Studies in mouse suggest that it may be involved in osteo- and chondrogenic differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

ITM2A Products(2)

mRNA	Protein	Name
NM_001171581.2	NP_001165052.1	integral membrane protein 2A isoform 2
NM_004867.5	NP_004858.1	integral membrane protein 2A isoform 1

ITM2A Protein Structure

BRICHOS

0
100
200
263 a.a.

Protein Preferred Names

Protein Names

integral membrane protein 2A

BRICHOS domain containing 2A

Related Diseases

Diseases

Alias

Cleft Palate With Or Without Ankyloglossia, X-Linked

Cleft Palate With Ankyloglossia	CPX
X-Linked Cleft Palate And Ankyloglossia	X-Linked Cleft Palate With Or Without Ankyloglossia
X-Linked Cleft Palate	X-Linked Cleft Palate With Ankyloglossia
Cleft Palate, With/Without Ankyloglossia, X-Linked

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06983	ITM2A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ITM2A	VGNC	VGNC:67865
Macaca mulatta	ITM2A	VGNC	VGNC:73798
Bos taurus	ITM2A	VGNC	VGNC:30339
Mus musculus	ITM2A	MGD	MGI:107706
Rattus norvegicus	ITM2A	RGD	RGD:1559423
Others	ITM2A	NCBI

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