1. Metabolic Enzyme/Protease
  2. Carboxypeptidase
  3. Hippuryl-L-phenylalanine

Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity.

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Hippuryl-L-phenylalanine Chemical Structure

Hippuryl-L-phenylalanine Chemical Structure

CAS No. : 744-59-2

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Description

Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity[1][2].

Molecular Weight

326.35

Formula

C18H18N2O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(C2=CC=CC=C2)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (766.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0642 mL 15.3210 mL 30.6419 mL
5 mM 0.6128 mL 3.0642 mL 6.1284 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0642 mL 15.3210 mL 30.6419 mL 76.6049 mL
5 mM 0.6128 mL 3.0642 mL 6.1284 mL 15.3210 mL
10 mM 0.3064 mL 1.5321 mL 3.0642 mL 7.6605 mL
15 mM 0.2043 mL 1.0214 mL 2.0428 mL 5.1070 mL
20 mM 0.1532 mL 0.7660 mL 1.5321 mL 3.8302 mL
25 mM 0.1226 mL 0.6128 mL 1.2257 mL 3.0642 mL
30 mM 0.1021 mL 0.5107 mL 1.0214 mL 2.5535 mL
40 mM 0.0766 mL 0.3830 mL 0.7660 mL 1.9151 mL
50 mM 0.0613 mL 0.3064 mL 0.6128 mL 1.5321 mL
60 mM 0.0511 mL 0.2553 mL 0.5107 mL 1.2767 mL
80 mM 0.0383 mL 0.1915 mL 0.3830 mL 0.9576 mL
100 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.7660 mL
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Hippuryl-L-phenylalanine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Hippuryl-L-phenylalanine
Cat. No.:
HY-137840
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