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item/HY-B0143

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Autophagy (4) Endogenous Metabolite (5) TGF-beta/Smad (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (2) Metabolic Disease (4)

Inhibitors & Agonists

Screening Libraries

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0143

Niacin 5+ Cited Publications Nicotinic acid; Vitamin B3	Autophagy Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases .

HY-B0143S2

Niacin-d4 Nicotinic acid-d₄; Vitamin B3-d₄	Autophagy Endogenous Metabolite	Metabolic Disease
Niacin-d₄ is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

HY-B0143S3

Niacin-13C6 Nicotinic acid-¹³C₆; Vitamin B3-¹³C₆	Autophagy Endogenous Metabolite	Metabolic Disease
Niacin- ¹³C₆ is the ¹³C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

HY-B0143A

Niacin hydrochloride Nicotinic acid HYdrochloride; Vitamin B3 HYdrochloride	Endogenous Metabolite Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases .

HY-B0143S4

Niacin-15N,13C3	Autophagy Endogenous Metabolite
Niacin- ¹⁵N, ¹³C₃ is the ¹³C and ¹⁵N labeled Niacin[1]. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[2][3].

HY-W013579

(S)-(+)-Carvone

D-Carvone
Others Others

(S)-(+)-Carvone (D Carvone) is a naturally occuring conmpound found in several food items and can be used in flavouring foods .

(S)-(+)-Carvone D-Carvone	Others	Others
(S)-(+)-Carvone (D Carvone) is a naturally occuring conmpound found in several food items and can be used in flavouring foods .

HY-W105318

Pentabromophenol PBP	TGF-beta/Smad Apoptosis	Cancer
Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs) .

Cat. No.	Product Name

HY-L0096V

Vitas-M Screening Compounds Library	1,400,000 compounds
Vitas-M Screening Compounds Library (stock) contains about 1,400,000 chemical substances. They are synthetic small molecule organic compounds for biological screening and lead optimization. Select any number of items as a "cherry pick".

HY-L055

Medicine Food Homology Compound Library	1709 compounds
Medicine Food Homology (MFH) means that some food themselves are medicines and there is no absolute boundary between them. MFH theory combines the function of food and medicine together scientifically and MFH materials can be used both for food and medicine. Besides nutritional value, MFH materials also have the functions in the prevention and treatment of disease and many other healthcare effects. Food as medicines has many benefits because of their safety while taking drugs will bring inevitable side effect to people. In order to ensure the safe use of functional food, National Health Commission of People's Republic of China made specific provisions on MFH items. More than 100 kinds of widely used MFH materials have been released. Based on MFH items released by National Health Commission, PRC, MCE carefully designs a unique collection of 1709 Medicine Food Homology Compounds with high safety that can be used for high throughput and high content screening for drug discovery.

Medicine Food Homology Compound Library

1709 compounds

Medicine Food Homology (MFH) means that some food themselves are medicines and there is no absolute boundary between them. MFH theory combines the function of food and medicine together scientifically and MFH materials can be used both for food and medicine. Besides nutritional value, MFH materials also have the functions in the prevention and treatment of disease and many other healthcare effects. Food as medicines has many benefits because of their safety while taking drugs will bring inevitable side effect to people. In order to ensure the safe use of functional food, National Health Commission of People's Republic of China made specific provisions on MFH items. More than 100 kinds of widely used MFH materials have been released.

Based on MFH items released by National Health Commission, PRC, MCE carefully designs a unique collection of 1709 Medicine Food Homology Compounds with high safety that can be used for high throughput and high content screening for drug discovery.

HY-L0088V

Life Chemicals 50K Diversity Library	50,240 compounds
Life Chemicals presents a number of exclusive Pre-Plated Diversity Sets composed of 50,240 novel compounds with optimal physicochemical properties selected from Life Chemicals collection of newly synthesized items by dissimilarity search with an average Tanimoto threshold of 82%. These Diverse Screening Sets are ideal starting points for customers looking for a wide range of dissimilarity to screen against a number of targets from different classes or where little information is available on targeted protein structure.

Life Chemicals 50K Diversity Library

50,240 compounds

Life Chemicals presents a number of exclusive Pre-Plated Diversity Sets composed of 50,240 novel compounds with optimal physicochemical properties selected from Life Chemicals collection of newly synthesized items by dissimilarity search with an average Tanimoto threshold of 82%. These Diverse Screening Sets are ideal starting points for customers looking for a wide range of dissimilarity to screen against a number of targets from different classes or where little information is available on targeted protein structure.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0143

Niacin 5+ Cited Publications Nicotinic acid; Vitamin B3	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Autophagy Endogenous Metabolite
Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases .

HY-W013579

(S)-(+)-Carvone D-Carvone	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Gymnaster koraiensis Other Diseases Plants Umbelliferae Disease Research Fields	Others
(S)-(+)-Carvone (D Carvone) is a naturally occuring conmpound found in several food items and can be used in flavouring foods .

HY-B0143A

Niacin hydrochloride Nicotinic acid HYdrochloride; Vitamin B3 HYdrochloride	Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Source classification Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases .

Cat. No.	Product Name	Chemical Structure

HY-B0143S2

Niacin-d4

Niacin-d₄ is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
HY-B0143S3

Niacin-13C6

Niacin- ¹³C₆ is the ¹³C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

Niacin-d4
Niacin-d₄ is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

Niacin-13C6
Niacin- ¹³C₆ is the ¹³C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

HY-B0143S4

Niacin-15N,13C3
Niacin- ¹⁵N, ¹³C₃ is the ¹³C and ¹⁵N labeled Niacin[1]. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[2][3].

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