2. Academic Validation
  3. Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0

Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0

  • J Chromatogr A. 2006 Jan 6;1101(1-2):204-13. doi: 10.1016/j.chroma.2005.10.009.
Christopher J Welch 1,  Jimmy O DaSilva,  Joseph Nti-Gyabaah,  Firoz Antia,  Kent Goklen,  Russell Boyd
Affiliations

Affiliation

  • 1 Merck Research Laboratories, Merck & Co. Inc., Rahway, NJ 07065, USA.
PMID: 16257000 DOI: 10.1016/j.chroma.2005.10.009
Abstract

Preparation and evaluation of a number of stationary phases for improved chromatographic purification of pneumocandin B0, a key intermediate in the synthesis of the Antifungal agent, Cancidas, has led to the identification of several Materials with potential for improved performance.

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