2. Academic Validation
  3. New eudesmane-type sesquiterpenoids from the root bark of Pseudolarix kaempferi

New eudesmane-type sesquiterpenoids from the root bark of Pseudolarix kaempferi

  • J Asian Nat Prod Res. 2015;17(12):1180-7. doi: 10.1080/10286020.2015.1117455.
Hai-Long Jiang 1 2,  Wei Ha 1,  Yan-Ping Shi 1
Affiliations

Affiliations

  • 1 a Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province , Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS) , Lanzhou 730000 , China.
  • 2 b College of Chemistry and Chemical Engineering , University of Chinese Academy of Sciences , Beijing 100049 , China.
PMID: 26666458 DOI: 10.1080/10286020.2015.1117455
Abstract

The phytochemical investigation of the root bark of Pseudolarix kaempferi yielded eight eudesmane-type sesquiterpenoids, including three new ones, 1α-hydroxyl-4(14)-en-β-dihydroagarafuran (1), 1α, 2α-diacetoxy-8β-isobutanoyloxy-9α-benzoyl oxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (7), and 1α-acetoxy-2 α-furancarbonyloxy-8β-isobutanoyloxy-9α-benzoyloxy-15β-(β-acetoxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (8). Herein the new compounds 7 and 8 were reported as a mixture. The molecular structures of the isolated compounds were elucidated on the basis of extensive spectroscopic analysis, including UV, IR, NMR, and MS, and comparison with the literature data.

Keywords

Pinaceae; Pseudolarix kaempferi; eudesmane; sesquiterpenoid.

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