2. Academic Validation
  3. Cytotoxic sesquiterpene lactones from Inula britannica

Cytotoxic sesquiterpene lactones from Inula britannica

  • Planta Med. 1998 Dec;64(8):752-4. doi: 10.1055/s-2006-957573.
E J Park,  J Kim
PMID: 9933993 DOI: 10.1055/s-2006-957573
Abstract

Cytotoxicity-guided fractionation of the flowers of Inula britannica led to the isolation of four sesquiterpene lactones, 4 alpha, 6 alpha-dihydroxyeudesman-8 beta, 12-olide (1), ergolide (2), 8-epi-helenalin (3), and bigelovin (4). Compound 1 was isolated as a new natural product. These compounds showed cytotoxicity against human tumor cell lines.

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