2. Anti-infection
  3. Bacterial Antibiotic
  4. Meropenem-d6

Meropenem-d6  (Synonyms: SM 7338-d6)

Cat. No.: HY-13678S Purity: ≥98.0%
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Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].

For research use only. We do not sell to patients.

Meropenem-d<sub>6</sub> Chemical Structure

Meropenem-d6 Chemical Structure

CAS No. : 1217976-95-8

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1 mg USD 250 In-stock
5 mg USD 880 In-stock
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Based on 1 publication(s) in Google Scholar

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Meropenem-d6 Related Antibodies

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Description

Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Meropenem-d6 Related Antibodies
Molecular Weight

389.50

Formula

C17H19D6N3O5S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

[H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=C(C(O)=O)N1C([C@]([C@@H](C)O)2[H])=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (256.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5674 mL 12.8370 mL 25.6739 mL
5 mM 0.5135 mL 2.5674 mL 5.1348 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5674 mL 12.8370 mL 25.6739 mL 64.1849 mL
5 mM 0.5135 mL 2.5674 mL 5.1348 mL 12.8370 mL
10 mM 0.2567 mL 1.2837 mL 2.5674 mL 6.4185 mL
15 mM 0.1712 mL 0.8558 mL 1.7116 mL 4.2790 mL
20 mM 0.1284 mL 0.6418 mL 1.2837 mL 3.2092 mL
25 mM 0.1027 mL 0.5135 mL 1.0270 mL 2.5674 mL
30 mM 0.0856 mL 0.4279 mL 0.8558 mL 2.1395 mL
40 mM 0.0642 mL 0.3209 mL 0.6418 mL 1.6046 mL
50 mM 0.0513 mL 0.2567 mL 0.5135 mL 1.2837 mL
60 mM 0.0428 mL 0.2139 mL 0.4279 mL 1.0697 mL
80 mM 0.0321 mL 0.1605 mL 0.3209 mL 0.8023 mL
100 mM 0.0257 mL 0.1284 mL 0.2567 mL 0.6418 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Meropenem-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Meropenem-d61217976-95-8SM 7338-d6BacterialAntibioticInhibitorinhibitorinhibit

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