2. PI3K/Akt/mTOR
  3. mTOR
  4. mTOR inhibitor-18

mTOR inhibitor-18 (Example 106) is a mTOR inhibitor. mTOR inhibitor-18 can be used for mTOR related research, such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.

For research use only. We do not sell to patients.

mTOR inhibitor-18 Chemical Structure

mTOR inhibitor-18 Chemical Structure

CAS No. : 2170358-67-3

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mTOR inhibitor-18 Related Antibodies

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Description

mTOR inhibitor-18 (Example 106) is a mTOR inhibitor. mTOR inhibitor-18 can be used for mTOR related research, such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders[1].

In Vivo

Rat PK properties of mTOR inhibitor-18 (Example 106)[1].

Dose (mg/kg) Cmax (μg/mL) AUC0-t (μg·h/mL) t1/2 (h) CL (L/h/kg) F%
IV (5 mg/kg) 21.2 41.455 1.416 0.122
PO (10 mg/kg) 9.987 73.44 3.258 0.247 89

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

431.51

Formula

C22H21N7OS
CAS No.
SMILES

S=C(NC1=CC=C(C2=NN3C=CC=C3C(N4CCOCC4)=N2)C=C1)NC5=CC=CN=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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mTOR inhibitor-18 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mTOR inhibitor-182170358-67-3mTOR inhibitor18mTOR inhibitor 18mTORMammalian target of Rapamycincancerimmune disorderscardiovascular diseaseviral infectioninflammationmetabolismendocrine function disordersneurological disordersInhibitorinhibitorinhibit

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