1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Integrin
  5. Integrin alpha 2 beta 1

Integrin alpha 2 beta 1

Cat. No. Product Name / Synonyms Species Source
  • HY-P700752
    Integrin alpha 2 beta 1 Protein, Human (HEK293, His)

    α2β1; Integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; VLA-2, GPIa-IIa, CD49b; Integrin alpha A1 β 1; alpha A1 β 1; β 1

    Human HEK293
    ITGA2 Protein, a transmembrane receptor, is involved in cell adhesion, platelet aggregation, and tumor metastasis. Dysregulation of ITGA2 Protein has been associated with various disorders, including thrombosis and cancer. Targeting ITGA2 Protein may offer potential therapeutic interventions in these conditions by modulating cell adhesion, inhibiting blood clot formation, and preventing tumor metastasis. Integrin alpha 2 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 2 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha 2 beta 1 Protein, Human (HEK293, His), has molecular weight of 110-140 kDa.
  • HY-P700753
    Integrin alpha 2 beta 1 Protein, Mouse (HEK293, His)

    α2β1; ITGA2&ITGB1; ITGA2; ITGB1;

    Mouse HEK293
    Integrin alpha-2/beta-1, a pivotal collagen receptor, centralizes platelet and cell adhesion to collagens, modulating collagen and collagenase gene expression. Beyond collagen-related functions, it contributes to force generation, extracellular matrix organization, and recognizes laminins, collagen C-propeptides, and E-cadherin. Mice with a null mutation in the alpha-2 subunit face early mortality, emphasizing its critical role in developmental processes. Structurally, forming a heterodimeric complex with beta-1, Integrin alpha-2/beta-1 interacts with HPS5 and RAB21, revealing multifaceted regulatory and signaling functions. Integrin alpha 2 beta 1 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha 2 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha 2 beta 1 Protein, Mouse (HEK293, His), has molecular weight of 128-138 kDa (ITGA2) & 105-115 kDa (ITGB1), respectively.
Cat. No. Product Name Effect Purity