2. Recombinant Proteins
  3. CAR-T Related Proteins Enzymes & Regulators
  4. Lyases (EC 4) Carbonic Anhydrase
  5. Carbonic Anhydrase 9 (CA IX)
  6. Carbonic Anhydrase 9 Protein, Mouse (HEK293, His)

Carbonic Anhydrase 9 Protein, Mouse (HEK293, His)

Cat. No.: HY-P77585
Handling Instructions

The Carbonic Anhydrase 9 protein is responsible for catalyzing the interconversion between carbon dioxide and water, as well as facilitating the conversion of carbonic acid into its dissociated ions, namely bicarbonate and hydrogen ions. Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is 359 a.a., with molecular weight of 50-53 kDa.

For research use only. We do not sell to patients.

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Description

The Carbonic Anhydrase 9 protein is responsible for catalyzing the interconversion between carbon dioxide and water, as well as facilitating the conversion of carbonic acid into its dissociated ions, namely bicarbonate and hydrogen ions. Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is 359 a.a., with molecular weight of 50-53 kDa.
Background

Carbonic Anhydrase 9 Protein, an enzyme, is involved in maintaining pH homeostasis and regulating tumor microenvironments. Dysregulation of Carbonic Anhydrase 9 Protein has been linked to tumor progression and metastasis. Targeting Carbonic Anhydrase 9 Protein may offer potential therapeutic interventions in cancer by modulating pH levels, disrupting tumor microenvironments, and impairing tumor growth.
Species

Mouse
Source

HEK293
Tag

C-His
Accession

Q8VHB5 (Q32-D390)
Gene ID
Molecular Construction
N-term
CA9 (Q32-D390)
Accession # Q8VHB5
His
C-term
Synonyms
CA9; CAIX; CA-IX; EC 4.2.1.1; G250; MN; P54/58N; PMW1; RCC
Molecular Weight

50-53 kDa
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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