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  5. CD200 Protein, Cynomolgus (HEK293, His)

CD200 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P700670
Handling Instructions

CD200 protein functions as a costimulator of T-cell proliferation and is implicated in the potential regulation of myeloid cell activity across various tissues. Through their N-terminal Ig-like domains, CD200 interacts with CD200R1, establishing a molecular interaction that likely contributes to the modulation of immune responses and cellular activities. CD200 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD200 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD200 Protein, Cynomolgus (HEK293, His) is 202 a.a., with molecular weight of 45-55 kDa.

For research use only. We do not sell to patients.

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Description

CD200 protein functions as a costimulator of T-cell proliferation and is implicated in the potential regulation of myeloid cell activity across various tissues. Through their N-terminal Ig-like domains, CD200 interacts with CD200R1, establishing a molecular interaction that likely contributes to the modulation of immune responses and cellular activities. CD200 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD200 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD200 Protein, Cynomolgus (HEK293, His) is 202 a.a., with molecular weight of 45-55 kDa.

Background

The CD200 protein plays a pivotal role in immune modulation, functioning as a costimulatory molecule that promotes T-cell proliferation. Additionally, CD200 is implicated in the potential regulation of myeloid cell activity across various tissues, as suggested by similarity-based inferences. The interaction between CD200 and its receptor, CD200R1, is facilitated through their respective N-terminal Ig-like domains. This interaction likely contributes to the regulatory processes involved in immune responses and myeloid cell function. The engagement of CD200 with CD200R1 underscores its significance in mediating immune cell communication and homeostasis, emphasizing its potential as a key player in immunomodulation.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

A0A2K5TQS2 (Q56-G257)

Gene ID

/

Molecular Construction
N-term
CD200 (Q56-G257)
Accession # A0A2K5TQS2
His
C-term
Synonyms
CD200; MOX1; MOX2; My033; MRC; OX-2; OX2
Molecular Weight

45-55 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CD200 Protein, Cynomolgus (HEK293, His)
Cat. No.:
HY-P700670
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