NKp46/NCR1 Protein, Cynomolgus (HEK293, His)

NKp46/NCR1 Protein, a pivotal cytotoxicity-activating receptor, enhances the efficiency of activated natural killer (NK) cells in destroying tumor cells. It interacts with CD3Z and FCER1G, potentially amplifying NK cell recognition and targeted lysis of cancerous cells. NKp46/NCR1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived NKp46/NCR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of NKp46/NCR1 Protein, Cynomolgus (HEK293, His) is 233 a.a., with molecular weight of 32-45 kDa.

NKp46/NCR1 Protein is a cell receptor that plays a crucial role in enhancing the efficiency of activated natural killer (NK) cells in destroying tumor cells. It acts as a cytotoxicity-activating receptor, potentially aiding in the process of tumor cell lysis by NK cells. NKp46/NCR1 Protein interacts with CD3Z and FCER1G, which may further enhance the ability of NK cells to recognize and target cancerous cells.

Immobilized Cynomolgus NKp46, His Tag at 0.5 μg/mL (100 μl/Well) on the plate. Dose response curve for Anti-NKp46 Antibody, hFc Tag with the EC₅₀ of ≤7.0 ng/mL determined by ELISA.

Cynomolgus

HEK293

C-His

Q95JB9 (A22-N254)

102115479  [NCBI]

35-45 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder

Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 100 mM L-arginine, pH 8.2 or PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.