Peroxiredoxin-2/PRDX2 Protein, Mouse (sf9, His)

Peroxiredoxin-2/PRDX2 protein is a thiol-specific peroxidase that effectively reduces hydrogen peroxide and organic hydroperoxides, protecting cells from oxidative stress and maintaining redox homeostasis. It also acts as a sensor for hydrogen peroxide-mediated signaling, regulating cellular responses to oxidative stress. Peroxiredoxin-2/PRDX2 Protein, Mouse (sf9, His) is the recombinant mouse-derived Peroxiredoxin-2/PRDX2 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Peroxiredoxin-2/PRDX2 Protein, Mouse (sf9, His) is 198 a.a., with molecular weight of ~24.1 kDa.

Peroxiredoxin-2/PRDX2 Protein functions as a thiol-specific peroxidase, adept at catalyzing the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. This protein assumes a crucial role in cellular protection against oxidative stress by efficiently detoxifying various peroxides, contributing significantly to the maintenance of cellular redox homeostasis. Additionally, PRDX2 acts as a sensor for hydrogen peroxide-mediated signaling events, implicating its involvement in modulating cellular responses to oxidative stress. Furthermore, it may participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating intracellular concentrations of H(2)O(2), suggesting its potential impact on signaling pathways associated with cellular growth and inflammation.

Mouse

Sf9 insect cells

N-His

Q61171 (M1-N198)

21672  [NCBI]

Approximately 24.1 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.