STK40 Protein, Human (sf9, His-GST)

The STK40 protein functions as a potential negative regulator, inhibiting NF-kappa-B and p53-mediated gene transcription. Its regulatory role implies fine-tuning of signaling pathways, indicating regulation of gene expression. STK40 Protein, Human (sf9, His-GST) is the recombinant human-derived STK40 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of STK40 Protein, Human (sf9, His-GST) is 435 a.a., with molecular weight of ~85 kDa.

STK40 Protein emerges as a potential negative regulator, exerting influence over NF-kappa-B and p53-mediated gene transcription. Its regulatory role implies an inhibitory function, suggesting involvement in fine-tuning the intricate signaling pathways associated with NF-kappa-B and p53. By acting as a negative regulator, STK40 may modulate the expression of genes under the control of these transcription factors, influencing cellular responses to various stimuli. Elucidating the specific mechanisms through which STK40 exerts its regulatory effects on NF-kappa-B and p53-mediated transcription could provide valuable insights into its role in cellular homeostasis and response to stressors. Further exploration of STK40's interactions and downstream effects may contribute to a comprehensive understanding of its function in the intricate network of transcriptional regulation.

Human

Sf9 insect cells

N-His;N-GST

Q8N2I9 (M1-K435)

83931  [NCBI]

Approximately 85 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.