2. Recombinant Proteins
  3. CAR-T Related Proteins
  4. TROP-2
  5. TROP-2 Protein, Mouse (HEK293, hFc)

TROP-2 Protein, Mouse (HEK293, hFc)

Cat. No.: HY-P74488
Handling Instructions

The TROP-2 protein functions as a growth factor receptor and has been shown to play a critical role in mediating cellular responses associated with growth regulation. Its involvement indicates that it plays a crucial role in signal transduction during cell growth. TROP-2 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived TROP-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TROP-2 Protein, Mouse (HEK293, hFc) is 246 a.a., with molecular weight of ~66 kDa.

For research use only. We do not sell to patients.

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Description

The TROP-2 protein functions as a growth factor receptor and has been shown to play a critical role in mediating cellular responses associated with growth regulation. Its involvement indicates that it plays a crucial role in signal transduction during cell growth. TROP-2 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived TROP-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TROP-2 Protein, Mouse (HEK293, hFc) is 246 a.a., with molecular weight of ~66 kDa.
Background

The TROP-2 protein appears to function as a growth factor receptor, suggesting a key role in mediating cellular responses associated with growth regulation. Its involvement in this capacity indicates that TROP-2 may play a crucial role in transducing signals that contribute to cellular growth processes. Further exploration of the specific signaling pathways and downstream effects mediated by TROP-2 as a growth factor receptor could provide valuable insights into its functional significance and potential implications in cellular development and homeostasis.
Species

Mouse
Source

HEK293
Tag

C-hFc
Accession

Q8BGV3 (Q25-Q270)
Gene ID

56753  [NCBI]
Molecular Construction
N-term
TROP-2 (Q25-Q270)
Accession # Q8BGV3
hFc
C-term
Synonyms
Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; TACSTD2; TROP2
Molecular Weight

Approximately 66 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

TROP-2 Protein, Mouse (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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