2. PI3K/Akt/mTOR
  3. mTOR Akt
  4. Royleanone

Royleanone, a diterpenoid isolated from plants, inhibits the proliferation of cancer cells by inducing cell cycle arrest and mitochondria-mediated apoptosis, also inhibits cell migration potential, inhibits mTOR/PI3/AKT signaling pathway in LNCaP prostate cancer cells.

For research use only. We do not sell to patients.

Royleanone Chemical Structure

Royleanone Chemical Structure

CAS No. : 6812-87-9

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Royleanone Related Antibodies

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Description

Royleanone, a diterpenoid isolated from plants, inhibits the proliferation of cancer cells by inducing cell cycle arrest and mitochondria-mediated apoptosis, also inhibits cell migration potential, inhibits mTOR/PI3/AKT signaling pathway in LNCaP prostate cancer cells[1].

IC50 & Target

mTOR/PI3/AKT[1]
In Vitro

Royleanone (0-200 μM; 48 h) inhibits the viability of LNCaP cancer cells in a dose-dependent manner, with an IC50 of 12.5 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Royleanone Related Antibodies
Molecular Weight

316.43

Formula

C20H28O3
CAS No.
SMILES

O=C1C(C(C)C)=C(O)C(C2=C1CC[C@@]3([H])C(C)(C)CCC[C@]23C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Royleanone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Royleanone6812-87-9NSC 122417NSC122417NSC-122417mTORAktMammalian target of RapamycinPKBProtein kinase BmTOR/PI3/AKTInhibitorinhibitorinhibit

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