1. Screening Libraries
  2. GPCR/G protein Compound Library

GPCR/G protein Compound Library

(483 bioactive Compounds) Cat. No.: HY-L006
Library Contents: XLSX PDF

A unique collection of 483 small inhibitors/regulators for drug development and GPCR research/screening.

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock
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  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

Description
& Advantages

•   A unique collection of 483 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, and ETA-receptor etc.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

Product Details
Formulation:
A collection of 483 active molecules supplied as pre-dissolved DMSO solutions
Container:
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Contents of GPCR/G protein Compound Library

Plate layout: HY-L006-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty PD 117519 NPS-2143 Taranabant 4-IBP Ro 67-7476 TCS-OX2-29 Plerixafor Bay 59-3074 Aprepitant Ticagrelor Empty
b Empty Zibotentan Vorapaxar Silodosin NPS-2143 (hydrochloride) SCH 527123 PD 123319 (ditrifluoroacetate) MK-3207 (Hydrochloride) MK-2894 SKF-82958 (hydrobromide) TAK-875 Empty
c Empty JDTic (dihydrochloride) Sarpogrelate (hydrochloride) Ponesimod Palosuran MK-6892 CJ-42794 Almorexant (hydrochloride) Otenabant Istradefylline SB-334867 (free base) Empty
d Empty SB-674042 TCS 1102 Tozadenant Risperidone Asenapine (maleate) Sitaxsentan (sodium) Fingolimod (hydrochloride) GSK1292263 BX471 Pitolisant (hydrochloride) Empty
e Empty Ozanimod MK-3697 IBMX Siponimod Atipamezole (hydrochloride) Angiotensin (1-7) 6H05 (trifluoroacetate) SKF 38393 (hydrochloride) Gonadorelin (acetate) Y16 Empty
f Empty Prucalopride (succinate) ML141 EHop-016 RBC8 CASIN BQU57 SRT3190 ADL-5859 ADX-47273 MRS 2578 Empty
g Empty WAY-100635 (maleate salt) CGS 21680 (Hydrochloride) Biperiden (Hydrochloride) MTEP (hydrochloride) Ambrisentan BRL 54443 BAN ORL 24 PF-4136309 JTC-801 Ki16425 Empty
h Empty Org 27569 WIN 55,212-2 (Mesylate) Montelukast (sodium) VU0152100 SB 242084 Xanomeline (oxalate) JNJ-7777120 SA4503 (dihydrochloride) Rupatadine (Fumarate) LY310762 Empty

Plate layout: HY-L006-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Betamethasone Beclometasone dipropionate Blonanserin Budesonide Clobetasol propionate Deflazacort Leuprolide (Acetate) Mometasone furoate MSX-122 Noscapine Empty
b Empty LY 344864 Angiotensin II human ICI 118,551 (hydrochloride) Telmisartan ZCL278 AMG 837 (calcium hydrate) UNC0642 CCG-1423 Rimonabant (Hydrochloride) Aclidinium (Bromide) Empty
c Empty Cisapride Prucalopride Tegaserod (maleate) Macitentan Vilazodone (Hydrochloride) Vilazodone Cimetidine Indacaterol (maleate) SB 271046 (Hydrochloride) SB-742457 Empty
d Empty AC-55541 Fosaprepitant (dimeglumine) VU0361737 Bilastine Haloperidol Olanzapine Quetiapine Amisulpride Aripiprazole Talnetant Empty
e Empty Pimavanserin Tandospirone TBPB MPEP (Hydrochloride) CPPHA Anamorelin Salirasib Cariprazine (hydrochloride) Mirabegron Adoprazine Empty
f Empty Tasimelteon Tarafenacin (D-tartrate) Lasmiditan (hydrochloride) NS-304 Taprenepag Azilsartan Avosentan ST-836 (hydrochloride) Reparixin (L-lysine salt) Prasugrel Empty
g Empty Ciproxifan (maleate) MBX-2982 Cabergoline OC000459 Lorcaserin (Hydrochloride) SB-269970 (hydrochloride) VU 0357121 rac-Rotigotine (Hydrochloride) Vortioxetine Vortioxetine (hydrobromide) Empty
h Empty RS 504393 RS 127445 BML-190 AM630 AM251 CTEP MDA 19 WZ811 Ebrotidine CP-809101 (hydrochloride) Empty

Plate layout: HY-L006-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty AR 231453 APD668 Piboserod GW9508 Kobe0065 kobe2602 SB-222200 NSC 23766 (trihydrochloride) Brexpiprazole Eprosartan (mesylate) Empty
b Empty AdipoRon AMD 3465 (hexahydrobromide) AM095 AM095 (free acid) Diphenmanil (methylsulfate) UNBS5162 Asenapine (hydrochloride) Setipiprant EHT 1864 Oncrasin-1 Empty
c Empty RU 24969 CID 16020046 SB225002 Grapiprant TG6-10-1 BD-1047 (dihydrobromide) Tolvaptan Olmesartan (medoxomil) Dexmedetomidine (hydrochloride) Medetomidine (hydrochloride) Empty
d Empty Agomelatine Alcaftadine Cetirizine (dihydrochloride) Loratadine Pramipexole (dihydrochloride) Loteprednol Etabonate Tiotropium (Bromide) Octreotide (acetate) Clozapine (N-oxide) Desmopressin (Acetate) Empty
e Empty (S)-Timolol (Maleate) Metoclopramide Metoclopramide (hydrochloride hydrate) Loxapine Loxapine (succinate) Strontium Ranelate Alarelin (Acetate) Ziprasidone (hydrochloride monohydrate) Iloperidone Guanfacine (hydrochloride) Empty
f Empty Naloxone (hydrochloride) Tripelennamine (hydrochloride) Salmeterol (xinafoate) Clopidogrel (hydrogen sulfate) Cortisone (acetate) Prednisolone Glycopyrrolate Meptazinol (hydrochloride) Zafirlukast Carteolol (hydrochloride) Empty
g Empty Acebutolol (hydrochloride) Atenolol Bambuterol (hydrochloride) Metoprolol (Succinate) Candesartan (Cilexetil) Losartan (potassium) Atosiban Mepenzolate (Bromide) NKP608 Valsartan Empty
h Empty LCZ696 Conivaptan (hydrochloride) Tranilast (trans-) K-Ras(G12C) inhibitor 12 N6-(4-Hydroxybenzyl)adenosine N6-Cyclohexyladenosine LY354740 GR79236 Orexin 2 Receptor Agonist ZM241385 Empty

Plate layout: HY-L006-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty SCH 58261 lumateperone (Tosylate) TY-52156 VU0357017 (hydrochloride) NAN-190 (hydrobromide) JNJ-63533054 Adomeglivant MK-571 (sodium salt) GSK137647A Clemizole (hydrochloride) Empty
b Empty Setiptiline Setiptiline (maleate) MK-0974 AMD-070 (hydrochloride) Laropiprant INCB3344 GW-1100 Calcium-Sensing Receptor Antagonists I Ibutamoren (Mesylate) ONO-AE3-208 Empty
c Empty LY404039 Plerixafor (octahydrochloride) Cinacalcet Cinacalcet (hydrochloride) Alosetron (Hydrochloride) SB-408124 CCG-63802 CCG-63808 Rotigotine Methylnaltrexone (Bromide) Empty
d Empty (R)-5-Hydroxymethyl Tolterodine SB-408124 (Hydrochloride) Alvimopan (dihydrate) Naltrexone (Hydrochloride) Naltrexone Cevimeline (hydrochloride hemihydrate) Cortodoxone Tianeptine Tianeptine (sodium salt) Solifenacin (Succinate) Empty
e Empty Rotigotine (Hydrochloride) B-HT 920 Darifenacin (hydrobromide) Bosentan Bosentan (hydrate) Ramelteon Bepotastine (Beslilate) Paliperidone Palonosetron (Hydrochloride) Fenspiride (Hydrochloride) Empty
f Empty Tolazoline (hydrochloride) Doxylamine (succinate) Decloxizine (dihydrochloride) Perphenazine Fluphenazine (dihydrochloride) Diphenidol (hydrochloride) Methacholine (chloride) Flibanserin Histamine (phosphate) Dapiprazole (hydrochloride) Empty
g Empty Regadenoson Amezinium (methylsulfate) Ondansetron (hydrochloride dihydrate) Ondansetron Carvedilol Formoterol (Fumarate) Tropisetron (Hydrochloride) Quetiapine (fumarate) Lurasidone (Hydrochloride) Azasetron (hydrochloride) Empty
h Empty Granisetron (Hydrochloride) (±)-Bisoprolol (hemifumarate) Doxazosin (mesylate) Pizotifen Sumatriptan (succinate) Topiramate Diphylline Prostaglandin E1 Pregnenolone Ticlopidine (hydrochloride) Empty

Plate layout: HY-L006-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Fluticasone (propionate) Ketotifen (fumarate) Lafutidine Ivabradine (hydrochloride) Detomidine (hydrochloride) Mizolastine Azatadine (dimaleate) Mianserin (hydrochloride) Mosapride (citrate) Alfuzosin Empty
b Empty Prazosin (hydrochloride) Tizanidine (hydrochloride) Tranilast Naratriptan (hydrochloride) Irbesartan Nebivolol (hydrochloride) Candesartan Rizatriptan (benzoate) L-(-)-α-Methyldopa (hydrate) Zolmitriptan Empty
c Empty Ipratropium (bromide) Meprednisone Desonide Methylprednisolone Oxybutynin Oxybutynin (chloride) Chlorprothixene Ranitidine (hydrochloride) Acetylcholine (chloride) Chlorpheniramine (maleate) Empty
d Empty Clemastine (fumarate) Diphenhydramine (hydrochloride) Roxatidine (Acetate Hydrochloride) Nizatidine Tropicamide Sulfisoxazole Irsogladine Triamcinolone Meclizine (dihydrochloride) Mirtazapine Empty
e Empty Phentolamine (mesylate) Cyproheptadine (hydrochloride) Terazosin (hydrochloride dihydrate) Moxonidine Famotidine Trimebutine (maleate) Betaxolol Betaxolol (hydrochloride) Levobetaxolol (hydrochloride) Almotriptan (malate) Empty
f Empty Naftopidil Atropine (sulfate monohydrate) Bethanechol (chloride) Chlorpromazine (hydrochloride) Clonidine (hydrochloride) Domperidone Fluocinolone (Acetonide) Gallamine Triethiodide Loperamide (hydrochloride) Olopatadine (hydrochloride) Empty
g Empty Oxymetazoline (hydrochloride) Phenoxybenzamine (hydrochloride) Salbutamol (hemisulfate) Sotalol (hydrochloride) Xylazine (hydrochloride) Naphazoline (hydrochloride) DL-Epinephrine L-Epinephrine (Bitartrate) L-Epinephrine Dopamine (hydrochloride) Empty
h Empty Ritodrine (hydrochloride) Clomipramine (hydrochloride) Scopine (hydrochloride) Trospium (chloride) Azelastine (hydrochloride) Isoprenaline (hydrochloride) (R)-(-)-Phenylephrine (hydrochloride) Xylometazoline (hydrochloride) Trazodone (hydrochloride) Brompheniramine (maleate) Empty

Plate layout: HY-L006-6

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Fluocinonide Arecoline (hydrobromide) Otilonium (bromide) Alverine (citrate) Benztropine (mesylate) Betahistine (dihydrochloride) Octopamine (hydrochloride) Trifluoperazine (dihydrochloride) Pemirolast (potassium) Desloratadine Empty
b Empty Homatropine (Bromide) Hydroxyzine (dihydrochloride) Flavoxate (hydrochloride) Tetrahydrozoline (hydrochloride) Guanabenz (Acetate) Propranolol (hydrochloride) Ramosetron (Hydrochloride) Ropinirole (hydrochloride) Ciclesonide Triamcinolone (acetonide) Empty
c Empty Epinastine UK 14,304 (tartrate) Tamsulosin Imidafenacin Ebastine Pilocarpine (Hydrochloride) Fenoldopam (mesylate) Cyclobenzaprine (hydrochloride) Dalasetron (Mesylate hydrate) Fimasartan Empty
d Empty Promethazine (hydrochloride) Fexofenadine (hydrochloride) Terbutaline (sulfate) Theophylline Suramin (sodium salt) Triflupromazine (hydrochloride) Pyrithioxin (dihydrochloride) Thioridazine (hydrochloride) Diphenylpyraline (hydrochloride) Pheniramine (Maleate) Empty
e Empty Fenoterol (hydrobromide) Molindone (hydrochloride) Sulpiride Levosulpiride Antazoline (hydrochloride) Ethamsylate Naftidrofuryl (oxalate) Labetalol (hydrochloride) Cyproheptadine (hydrochloride sesquihydrate) Histamine Empty
f Empty Carbamoylcholine (chloride) Dimenhydrinate Promazine (hydrochloride) Droperidol Trihexyphenidyl (hydrochloride) Citalopram (hydrobromide) Mebhydrolin (napadisylate) Adrenalone (hydrochloride) Homatropine (methylbromide) Esmolol (hydrochloride) Empty
g Empty Azaperone Deoxycorticosterone (acetate) Benzetimide (hydrochloride) Chlorphenoxamine Clebopride (malate) Methoxyphenamine (Hydrochloride) Levodropropizine Solifenacin (hydrochloride) Baohuoside I Ferulic acid (sodium) Empty
h Empty Synephrine (hydrochloride) Matrine Scopolamine (hydrobromide) L-DOPA L-Glutamine L-Hyoscyamine Hydrocortisone Harmine Tetrahydroberberine Tyr-Gly-Gly-Phe-Met-OH Empty

Plate layout: HY-L006-7

1 2 3 4 5 6 7 8 9 10 11 12
a Empty TRAP-6 Neuromedin N Angiotensin II 5-valine Empty Empty Empty Empty Empty Empty Empty Empty
b Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
c Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
d Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
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GPCR/G protein Compound Library
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