Protease Inhibitor Library

Cat. No.: HY-L147: Library Contents: XLSX PDF SDF

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. Proteases play important roles in regulating multiple biological processes in all living organisms, such as regulating the fate, localization, and activity of many proteins, modulating protein-protein interactions, creating new bioactive molecules, contributing to the processing of cellular information, and generating, transducing, and amplifying molecular signals.

Proteases are important targets in drug discovery. Some protease inhibitors are often used as anti-virus drugs and anti-cancer drugs. MCE offers a unique collection of 604 protease inhibitors. MCE Protease Inhibitor Library is critical for drug discovery and development.

MCE Protease Inhibitor Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 597 compounds supplied in 10 mM solution, 4 compounds supplied in 2 mM solution and 3 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

Size (Pre-dissolved Solution or Solid)	Price	Stock
30 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock
50 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock
100 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock
2 × 100 μL/well Solution 10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution	Get quote	In-stock

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Publications Citing Use of MCE Compound Libraries

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Description & Advantages	• A unique collection of 604 protease Inhibitors for high throughput screening (HTS) and high content screening (HCS). • A useful tool for the study of critical for drug discovery and development. • Target diverse, medicinally active and cell permeable. • Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA. • More detailed compound information with structure, IC50, and other chemical & biological data. • High purity and quality validated by NMR and LC/MS.
Product Details	Formulation: A collection of 604 protease inhibitors supplied as pre-dissolved Solutions or Solid Solution: 597 compounds supplied in 10 mM solution, 4 compounds supplied in 2 mM solution, 3 compounds supplied in 3 mg/mL solution. Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty. 384-well plate: the first two columns and the last two columns are left empty. Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know. Container: 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode Storage: In solvent: -80°C 2 years, -20°C 1 year; Powder: -20°C 3 years, 4°C 2 years Shipping: Blue ice or dry ice
Documentation	XLSX PDF Library Handling Instructions (351 KB)

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Protease Inhibitor Library

Publications Citing Use of MCE Compound Libraries

Description

Product Details

Documentation

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