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Results for "

1A-116

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-104064
    1A-116
    5 Publications Verification

    		 Ras Apoptosis Cancer
    1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo .
    <em>1A-116</em>
  • HY-144899
    ASR-490

    		Notch Cancer
    ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and Notch1/HCT116 in xenotransplanted mice .
    ASR-490
  • HY-RS01711
    C1orf116 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    C1orf116 Human Pre-designed siRNA Set A contains three designed siRNAs for C1orf116 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    C1orf116 Human Pre-designed siRNA Set A
    C1orf116 Human Pre-designed siRNA Set A
  • HY-155059
    Antimycobacterial agent-6

    		Bacterial Infection
    Antimycobacterial agent-6 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis (Mtb)，targeting to both wild-type and fluoroquinolone-resistant Mtb strains. Antimycobacterial agent-6 inhibits Mtb DprE1-C387S mutant with MIC90s of 0.9 μM (H37Rv)，0.9 μM (MoxR)，0.5 μM (DprE1-P116S)，respectively .
    Antimycobacterial agent-6

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