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Results for "

CD44

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Biochemical Assay Reagents (1) Calmodulin (1) Caspase (1) DNA/RNA Synthesis (1) Endogenous Metabolite (1) HDAC (1) Histone Methyltransferase (1) PAI-1 (1) Reactive Oxygen Species (1) Small Interfering RNA (siRNA) (1) VEGFR (1) Wnt (2) β-catenin (2)
By Research Areas:	Cancer (10) Inflammation/Immunology (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-149898

*HA-CD44* interaction inhibitor 1**	Others	Cancer
Antitumor agent-109 (compound 6) is an inhibitor of hyaluronic acid (HY-B0633A) targeting to CD44, as well as an anti-tumor agent. Hyaluronic acid interacts with differentiation cluster 44 (CD44) and is involved in tumor growth and invasion. Antitumor agent-109 inhibits MDA-MB-231 cells with EC50 value of 0.59 μM .

HY-P2230

Angstrom6 A6 Peptide	PAI-1	Cancer
Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the uPA/uPAR cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling .

HY-149897

*HA-CD44* interaction inhibitor 2**	Biochemical Assay Reagents	Cancer
Antitumor agent-108 (compound 5) is an Hyaluronic acid (HA)-CD44 interaction inhibitor that effectively disrupts the integrity of cancer spheroids. Antitumor agent-108 also exhibits antiproliferative activity against cancer cells .

HY-RS02248

CD44 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CD44 Human Pre-designed siRNA Set A contains three designed siRNAs for CD44 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD44 Human Pre-designed siRNA Set A CD44 Human Pre-designed siRNA Set A

HY-E70290

N-Acetylgalactosaminyltransferase 1 GALNT1	Endogenous Metabolite β-catenin Wnt	Cancer
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer promotes the Wnt/β-catenin signaling pathway through abnormal O-glycosylation of CD44, thereby enhancing malignancy. N-Acetylgalactosaminyltransferase 1 plays a crucial role in cancer growth and metastasis by modifying O-glycosylation of various glycoproteins, such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3 .

HY-156096

HDAC3-IN-2	HDAC Histone Methyltransferase Caspase Apoptosis DNA/RNA Synthesis	Cancer
HDAC3-IN-2 (compound 4i) is a pyrazinyl hydrazide-based HDAC3 inhibitor (IC₅₀: 14 nM) that efficiently targets triple-negative breast cancer cells. HDAC3-IN-2 is cytotoxic with an IC₅₀ of 0.55 μM against 4T1 and an IC₅₀ of 0.74 μM against MDA-MB-231. HDAC3-IN-2 has anti-tumor efficacy in vivo in tumor-bearing mouse models, selectively increasing the acetylation levels of H3K9, H3K27 and H4K12, increasing the contents of apoptosis-related caspase-3, caspase-7 and cytochrome c, and reducing Proliferation-related Bcl-2, CD44, EGFR, and Ki-67 levels .

HY-100914

A-7 hydrochloride

Ophobolin A
Calmodulin Cancer

A-7 hydrochloride (Ophobolin A) is a calmodulin antagonist and can be used for the research of cancer .

A-7 hydrochloride Ophobolin A	Calmodulin	Cancer
A-7 hydrochloride (Ophobolin A) is a calmodulin antagonist and can be used for the research of cancer .

HY-148918

E722-2648	β-catenin Wnt	Cancer
E722-2648 is a potent β-catenin/BCL9 complex inhibitor. E722-2648 specifically inhibits β-catenin/BCL9 complex formation and Wnt activity. E722-2648 disrupts cholesterol homeostasis via increased cholesterol esterification and lipid droplet accumulation. E722-2648 has antitumor activity .

HY-143491

VS 8	VEGFR Apoptosis Reactive Oxygen Species	Cancer
VS 8 (Compound VS 8) is a potent, orally active VEGFR-2 inhibitor with significant anti-angiogenic effects. VS 8 induces cancer cell apoptosis and migration. VS 8 is active against CSCs (Cancer stem cells) .

Cat. No.	Product Name	Target	Research Area

HY-P2230

Angstrom6 A6 Peptide	PAI-1	Cancer
Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the uPA/uPAR cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling .

HY-P2284

AD 01	Peptides	Cancer
AD 01, a 24 amino acid peptide of FKBPL (FK506-binding protein like), possesses potent anti-angiogenic activity. AD 01 bind to the CD44 receptor and inhibit tumour cell migration in a CD44 dependant manner .

HY-P5351

Hyaluronan-binding peptide, biotin labeled	Peptides	Others
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)

Cat. No.	Product Name	Target	Research Area

HY-P99126

Anti-Mouse CD44 Antibody (IM7)

Inhibitory Antibodies Inflammation/Immunology

Anti-Mouse CD44 Antibody is an anti-mouse CD44 IgG2b antibody inhibitor derived from host Rat.

*Anti-Mouse CD44* Antibody (IM7)**	Inhibitory Antibodies	Inflammation/Immunology
Anti-Mouse CD44 Antibody is an anti-mouse CD44 IgG2b antibody inhibitor derived from host Rat.

HY-P99281

Bivatuzumab BIWA 4; Anti-CD44 Recombinant Antibody	Inhibitory Antibodies	Cancer
Bivatuzumab (Anti-CD44 Recombinant Antibody; BIWA 4) is a humanized monoclonal antibody directed against *CD44v6. CD44v6* could acts as a sarcoma target for CAR-redirected CIK cells .

Species:	Human (5) Mouse (1) Cynomolgus (1)
Tag:	His (4) Avi (1) Fc (3)
Source:	HEK293 (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P74291

	CD44 Protein, Mouse (HEK293, His) CD44 antigen; CDw44; Epican; ECMR-III; CD44; LHR; MDU2	Mouse	HEK293
	The CD44 protein binds to hyaluronic acid and TGF-β receptors and contributes to cytokine function. CD44 is involved in T cell activation, protein phosphorylation, and Wnt signaling and is strategically located in the plasma membrane and microvilli. CD44 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD44 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD44 Protein, Mouse (HEK293, His) is 200 a.a., with molecular weight of ~37 kDa.

HY-P70507

	CD44 Protein, Human (HEK293, His) CD44 Antigen; CDw44; Epican; Extracellular Matrix Receptor III; ECMR-III; GP90 Lymphocyte Homing/Adhesion Receptor; HUTCH-I; Heparan Sulfate Proteoglycan; Hermes Antigen; Hyaluronate Receptor; Phagocytic Glycoprotein 1; PGP-1; Phagocytic Glycoprotein I; PGP-I; CD44; LHR	Human	HEK293
	CD44 is a cell surface receptor that plays a key role in calcium mobilization and actin-mediated cytoskeletal reorganization, cell migration, and adhesion. CD44 Protein, Human (HEK293, His) is the recombinant human-derived CD44 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD44 Protein, Human (HEK293, His) is 200 a.a., with molecular weight of 38-50 kDa.

HY-P74293

	CD44 Protein, Human (220a.a, HEK293, Fc) CD44 antigen; CDw44; Epican; ECMR-III; CD44; LHR; MDU2	Human	HEK293
	CD44 is a cell surface receptor that plays a key role in calcium mobilization and actin-mediated cytoskeletal reorganization, cell migration, and adhesion. CD44 Protein, Human (220a.a, HEK293, Fc) is the recombinant human-derived CD44 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD44 Protein, Human (220a.a, HEK293, Fc) is 200 a.a., with molecular weight of ~76 kDa.

HY-P700402

	CD44 Protein, Human (Biotinylated, HEK293) CD44 Antigen; CDw44; Epican; Extracellular Matrix Receptor III; ECMR-III; GP90 Lymphocyte Homing/Adhesion Receptor; HUTCH-I; Heparan Sulfate Proteoglycan; Hermes Antigen; Hyaluronate Receptor; Phagocytic Glycoprotein 1; PGP-1; Phagocytic Glycoprotein I; PGP-I; CD44; LHR	Human	HEK293
	CD44 is a cell surface receptor that plays a key role in calcium mobilization and actin-mediated cytoskeletal reorganization, cell migration, and adhesion. CD44 Protein, Human (Biotinylated, HEK293) is the recombinant human-derived CD44 protein, expressed by HEK293 , with C-Avi, C-mFc labeled tag. The total length of CD44 Protein, Human (Biotinylated, HEK293) is 200 a.a., with molecular weight of 51 kDa.

HY-P700439

	CD44 Protein, Macaca fascicularis (HEK293, His) CD44 Antigen; CDw44; Epican; Extracellular Matrix Receptor III; ECMR-III; GP90 Lymphocyte Homing/Adhesion Receptor; HUTCH-I; Heparan Sulfate Proteoglycan; Hermes Antigen; Hyaluronate Receptor; Phagocytic Glycoprotein 1; PGP-1; Phagocytic Glycoprotein I; PGP-I; CD44; LHR	Cynomolgus	HEK293
	The CD44 protein is characterized by a lack of conserved residues critical for annotation of propagation signatures. This defective residue in CD44 prevents the propagation of specific functional features associated with this protein. CD44 Protein, Macaca fascicularis (HEK293, His) is the recombinant cynomolgus-derived CD44 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD44 Protein, Macaca fascicularis (HEK293, His) is 630 a.a., with molecular weight of 71.6 kDa.

HY-P700966

	CD44 Protein, Human (242a.a, HEK293, hFc) CD44; CDw44; Epican; ECMR-III; LHR; MDU2; MDU3; MIC4; PGP-I; CSPG8; HCELL; HUTCH-I; IN; MC56	Human	HEK293
	CD44 is a cell surface receptor that plays a key role in calcium mobilization and actin-mediated cytoskeletal reorganization, cell migration, and adhesion. CD44 Protein, Human (242a.a, HEK293, hFc) is a recombinant protein dimer complex containing human-derived CD44 protein, expressed by HEK293 , with C-hFc labeled tag. CD44 Protein, Human (242a.a, HEK293, hFc), has molecular weight of 70-100 kDa.

HY-P700967

	CD44 Protein, Human (242a.a, HEK293, His) CD44; CDw44; Epican; ECMR-III; LHR; MDU2; MDU3; MIC4; PGP-I; CSPG8; HCELL; HUTCH-I; IN; MC56	Human	HEK293
	CD44 is a cell surface receptor that plays a key role in calcium mobilization and actin-mediated cytoskeletal reorganization, cell migration, and adhesion. CD44 Protein, Human (242a.a, HEK293, His) is a recombinant protein dimer complex containing human-derived CD44 protein, expressed by HEK293 , with C-His labeled tag. CD44 Protein, Human (242a.a, HEK293, His), has molecular weight of 45-68 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P80062

CD44 Antibody	WB, IHC-P, FC	Human, Mouse
CD44 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 82 kDa, targeting to CD44. It can be used for WB,IHC-P,FC assays with tag free, in the background of Human, Mouse.

HY-P80602

CD44 Antibody (YA801) CD44; LHR; MDU2; MDU3; MIC4; CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycopr	WB, IHC-F, IHC-P, ICC/IF, IP	Human
CD44 Antibody (YA801) is a non-conjugated and Mouse origined monoclonal antibody about 82 kDa, targeting to CD44 (2H12). It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human.

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