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CHI3L1

" in MedChemExpress (MCE) Product Catalog:

4

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4

Recombinant Proteins

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  • HY-P700039AF
    Animal-Free CHI3L1 Protein, Human (His)

    CHItinase-3-Like protein 1; 39 kDa Synovial Protein; Cartilage Glycoprotein 39; CGP-39; GP-39; hCGP-39; YKL-40; CHI3L1

    		 Human E. coli
    Chitinase-3-like protein 1 (CHI3L1) is a carbohydrate-binding lectin with a specific affinity for chitin, although it lacks chitinase activity. Its main role extends beyond chitin degradation, as it is implicated in tissue remodeling and cellular responses to environmental changes. CHI3L1 plays a crucial role in T-helper cell type 2 (Th2) inflammatory responses and IL-13-induced inflammation, influencing allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation, and the differentiation of M2 macrophages. Additionally, it facilitates the invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. CHI3L1 is involved in the activation of the AKT1 signaling pathway, leading to IL8 production in colonic epithelial cells. Furthermore, it regulates antibacterial responses in the lungs, contributing to macrophage bacterial killing, controlling bacterial dissemination, and enhancing host tolerance. In lung tissues, CHI3L1 also plays a role in regulating hyperoxia-induced injury, inflammation, and epithelial apoptosis. Structurally, CHI3L1 functions as a monomer. Animal-Free CHI3L1 Protein, Human (His) is the recombinant human-derived animal-FreeCHI3L1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free CHI3L1 Protein, Human (His) is 362 a.a., with molecular weight of ~41.43 kDa.
  • HY-P70030
    CHI3L1 Protein, Human (HEK293, His)
    2 Publications Verification

    rHuCHItinase-3-like protein 1/CHI3L1, His; CHItinase-3-Like protein 1; 39 kDa Synovial Protein; Cartilage Glycoprotein 39; CGP-39; GP-39; hCGP-39; YKL-40; CHI3L1

    		 Human HEK293
    The CHI3L1 protein is a binding lectin that lacks chitinase activity. CHI3L1 contributes to tissue remodeling, cellular adaptation to environmental changes, and T helper type 2 inflammatory responses. CHI3L1 also controls hyperoxia-induced injury, inflammation, and epithelial cell apoptosis. CHI3L1 Protein, Human (HEK293, His) is the recombinant human-derived CHI3L1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CHI3L1 Protein, Human (HEK293, His) is 362 a.a., with molecular weight of 41-48 kDa.
  • HY-P76702
    CHI3L1 Protein, Mouse (381a.a, HEK293, His)

    CHItinase-3-Like protein 1; 39 kDa Synovial Protein; CGP-39; GP-39; hCGP-39; YKL-40

    		 Mouse HEK293
    The CHI3L1 protein is a carbohydrate-binding lectin with a preference for chitin that is involved in tissue remodeling and cellular adaptation to environmental changes. It is involved in Th2 inflammation, IL-13-induced inflammation, allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation, M2 macrophage differentiation and pathogenic intestinal bacterial invasion. CHI3L1 Protein, Mouse (381a.a, HEK293, His) is the recombinant mouse-derived CHI3L1 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CHI3L1 Protein, Mouse (381a.a, HEK293, His) is 360 a.a., with molecular weight of ~40.83 kDa.
  • HY-P78365
    CHI3L1 Protein, Mouse (360a.a, HEK293, His)

    BRP39; CGP-39; GP-39; CHIl1; ASRT7; FLJ38139; HC-gp39; YKL-40; YKL40; YYL-40; AW208766; CHI3L1; CHItinase 3 like 1

    		 Mouse HEK293
    CHI3L1 Protein, a carbohydrate-binding lectin with a preference for chitin, participates in tissue remodeling and cellular adaptation to environmental changes. It is involved in Th2 inflammation, IL-13-induced inflammation, allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation, M2 macrophage differentiation, and pathogenic enteric bacteria invasion. In colonic epithelial cells, it activates the AKT1 signaling pathway, leading to IL8 production. It also enhances antibacterial responses in the lung and regulates hyperoxia-induced injury and inflammation. CHI3L1 exists as a monomer. CHI3L1 Protein, Mouse (360a.a, HEK293, His) is the recombinant mouse-derived CHI3L1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CHI3L1 Protein, Mouse (360a.a, HEK293, His) is 360 a.a., with molecular weight of 42-50 kDa.

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