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Results for "

CMA

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Peptides

2

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101106
    AR7
    5 Publications Verification

    		 RAR/RXR Neurological Disease Cancer
    AR7 is an atypical RARA/RARα (retinoic acid receptor, alpha) antagonist. AR7 specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy .
    AR7
  • HY-134923
    CA77.1
    2 Publications Verification

    		 Autophagy Neurological Disease
    CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics. CA77.1 is a derivative of AR7 (HY-101106) and can increase the expression of the lysosomal receptor LAMP2A in lysosomes. CA77.1 improves behavior and neuropathology in PS19 mice model and can be used for alzheimer's disease research .
    CA77.1
  • HY-N1724
    Concanamycin A
    Maximum Cited Publications
    9 Publications Verification

    Antibiotic X 4357B; Folimycin; X 4357B
    Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
    Concanamycin A
  • HY-RS02853
    CMA1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    CMA1 Human Pre-designed siRNA Set A contains three designed siRNAs for CMA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CMA1 Human Pre-designed siRNA Set A
    CMA1 Human Pre-designed siRNA Set A
  • HY-RS02854
    CMAS Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    CMAS Human Pre-designed siRNA Set A contains three designed siRNAs for CMAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CMAS Human Pre-designed siRNA Set A
    CMAS Human Pre-designed siRNA Set A
  • HY-112486
    TA-316

    Megakaryocytes/platelets inducing agent

    		 Cyclin G-associated Kinase (GAK) Cardiovascular Disease
    TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells .
    TA-316
  • HY-112483
    QX77
    3 Publications Verification

    		 Autophagy Cancer
    QX77 is a chaperone-mediated autophagy (CMA) activator and upregulates LAMP2A expression in vitro. QX77 induces Rab11 upregulation, rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells . QX77 can impede self-renewal and promote differentiation of ES cells .
    QX77
  • HY-155747
    FDW028

    		Autophagy Cancer
    FDW028 a potent and highly selective FUT8 inhibitor. FUT8 exhibits potent anti-tumor activity by defucosylation and impelling lysosomal degradation of B7-H3 through the chaperone-mediated autophagy (CMA) pathway. FDW028 can be used for metastatic colorectal cancer (mCRC) research .
    FDW028
  • HY-P1098B
    Ac2-26 ammonium
    3 Publications Verification

    		 IKK Inflammation/Immunology
    Ac2-26 ammonium is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 ammonium induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ammonium ameliorates lung ischemia-reperfusion injury. Ac2-26 ammonium also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .
    Ac2-26 ammonium

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