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Results for "

Desipramine

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1272AS
    Desipramine-d4

    		Dopamine Transporter Serotonin Transporter Others
    Desipramine-d4 is the deuterium labeled Desipramine[1].
    <em>Desipramine</em>-d4
  • HY-B1272AS1
    Desipramine-d3

    		Dopamine Transporter Serotonin Transporter Metabolic Disease
    Desipramine-d3 is the deuterium labeled Desipramine. Desipramine is a tricyclic psychotic compound, possessing antidepressant activity. Desipramine inhibits the norepinephrine reuptake receptor in the central nervous system and reduces the sleep-related loss of genioglossus activity, can be used to research the improvement of pharyngeal collapsibility[1][2][3].
    <em>Desipramine</em>-d3
  • HY-B1272
    Desipramine hydrochloride
    5+ Cited Publications

    		 Dopamine Transporter Serotonin Transporter Neurological Disease Cancer
    Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively.
    <em>Desipramine</em> hydrochloride
  • HY-B1272A
    Desipramine

    		Adrenergic Receptor Neurological Disease
    Desipramine is a tricyclic psychotic compound, possessing antidepressant activity. Desipramine inhibits the norepinephrine reuptake receptor in the central nervous system and reduces the sleep-related loss of genioglossus activity, can be used to research the improvement of pharyngeal collapsibility .
    <em>Desipramine</em>
  • HY-132461S
    2-Hydroxy Desipramine-d3

    		Isotope-Labeled Compounds Others
    2-Hydroxy Desipramine-d3 is the deuterium labeled 2-Hydroxy Desipramine[1].
    2-Hydroxy <em>Desipramine</em>-d3
  • HY-132461S1
    2-Hydroxy Desipramine-d6

    		Isotope-Labeled Compounds Others
    2-Hydroxy Desipramine-d6 is the deuterium labeled 2-Hydroxy Desipramine[1].
    2-Hydroxy <em>Desipramine</em>-d6
  • HY-12390
    Lofepramine

    Lopramine

    		 Others Neurological Disease
    Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties .
    Lofepramine
  • HY-12390A
    Lofepramine hydrochloride

    Lopramine hydrochloride

    		 Others Neurological Disease
    Lofepramine (Lopramine) hydrochloride is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine hydrochloride stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine hydrochloride may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine hydrochloride has significant anxiolytic efficacy in addition to its antidepressant properties .
    Lofepramine hydrochloride
  • HY-12390S
    Lofepramine-d3

    		Isotope-Labeled Compounds Neurological Disease
    Lofepramine-d3 (Lopramine-d3) is the deuterium labeled Lofepramine. Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties[1].
    Lofepramine-d3

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