E.coli metabolite

By Targets:	Endogenous Metabolite (11) Bacterial (2)
By Research Areas:	Infection (7) Metabolic Disease (2)

Targets Recommended: Drug Metabolite Endogenous Metabolite

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-133154

Carboxyaminoimidazole ribotide CAIR; 4-Carboxy-AIR	Endogenous Metabolite	Infection
Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .

HY-141465

3-Hydroxybutyryl-CoA	Endogenous Metabolite	Metabolic Disease
3-Hydroxybutyryl-CoA is a metabolite which can be found in mouse or E.coli, et al. 3-Hydroxybutyryl-CoA has a 3-hydroxybutanoyl as the S-acyl component, and is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan .

HY-E70248

S-(3-Hydroxydodecanoate)-CoA	Endogenous Metabolite	Others
S-(3-Hydroxydodecanoate)-CoACoenzyme A, a Coenzyme A, is a metabolite that can be found or produced in E. coli (strain K12, MG1655) .

HY-154871

α-D-Glucosamine 1-phosphate	Endogenous Metabolite	Others
α-D-Glucosamine 1-phosphate is an E.coli metabolite. α-D-Glucosamine 1-phosphate is one of the precursors of peptidoglycan synthesis .

HY-148197

Glutathionylspermidine

Endogenous Metabolite Others

Glutathionylspermidine is a peptide and a metabolite of E. coli .

Glutathionylspermidine	Endogenous Metabolite	Others
Glutathionylspermidine is a peptide and a metabolite of E. coli .

HY-113270

Actinine γ-Butyrobetaine; Deoxycarnitine	Endogenous Metabolite	Metabolic Disease
Actinine (γ-Butyrobetaine) is an amino acid betaine aminobutyric acid zwitterion. Actinine acts as both a human metabolite and a metabolite of E. coli .

HY-N8515B

UDP-3-O-acyl-GlcNAc diammonium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Endogenous Metabolite	Others
UDP-3-O-acyl-GlcNAc diammonium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N8515

UDP-3-O-acyl-GlcNAc UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine	Endogenous Metabolite	Infection
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-W585865

UDP-3-O-acyl-GlcNAc Tris UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris	Endogenous Metabolite	Infection
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) Tris is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N8515C

UDP-3-O-acyl-GlcNAc disodium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium	Endogenous Metabolite	Infection Others
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N8060

Orotidine 5′-monophosphate Orotidine monophosphate; Orotidylic acid	Endogenous Metabolite	Others
Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase .

HY-N8301

Ilicicolin F LL-Z 1272ζ	Bacterial	Infection
Ilicicolin F is a fungal metabolite that has been found in Fusarium and has diverse biological activities. It inhibits T. vivax alternative oxidase and the E. coli ubiquinol oxidase cytochrome bo (IC₅₀s=0.43 and 0.37 μM, respectively) but not the E. coli ubiquinol oxidase cytochrome bd (IC₅₀=85 μM).2 Ilicicolin F is active against the fungi A. fumigatus and C. albicans (MICs=1.66-3.33 and 6.66-13.33 μg/mL, respectively). It is cytotoxic to HeLa cells with an EC₅₀ value of 0.003 μg/mL.

HY-N7307

Pachybasin	Bacterial	Infection
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

HY-N8256

(–)-Mycousnine Mycousunin	Others	Infection
(–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid (HY-N0656) originally isolated from M. nawae that has antibacterial and antifungal activities. It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus (MICs=4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteria E. coli, S. typhimurium, and K. pneumoniae (MICs=>128 g/ml for all).2 (–)-Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans (MICs=25, 25, and 100 μg/mL, respectively).

Cat. No.	Product Name	Target	Research Area

HY-148197

Glutathionylspermidine

Endogenous Metabolite Others

Glutathionylspermidine is a peptide and a metabolite of E. coli .

Glutathionylspermidine	Endogenous Metabolite	Others
Glutathionylspermidine is a peptide and a metabolite of E. coli .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-133154

Carboxyaminoimidazole ribotide CAIR; 4-Carboxy-AIR	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .

HY-141465

3-Hydroxybutyryl-CoA	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
3-Hydroxybutyryl-CoA is a metabolite which can be found in mouse or E.coli, et al. 3-Hydroxybutyryl-CoA has a 3-hydroxybutanoyl as the S-acyl component, and is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan .

HY-154871

α-D-Glucosamine 1-phosphate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
α-D-Glucosamine 1-phosphate is an E.coli metabolite. α-D-Glucosamine 1-phosphate is one of the precursors of peptidoglycan synthesis .

HY-148197

Glutathionylspermidine	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glutathionylspermidine is a peptide and a metabolite of E. coli .

HY-113270

Actinine γ-Butyrobetaine; Deoxycarnitine	Structural Classification Natural Products Microorganisms Marine algae Source classification Marine natural products Endogenous metabolite	Endogenous Metabolite
Actinine (γ-Butyrobetaine) is an amino acid betaine aminobutyric acid zwitterion. Actinine acts as both a human metabolite and a metabolite of E. coli .

HY-N8515B

UDP-3-O-acyl-GlcNAc diammonium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc diammonium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N8515

UDP-3-O-acyl-GlcNAc UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine	Structural Classification Natural Products Microorganisms Source classification	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-W585865

UDP-3-O-acyl-GlcNAc Tris UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) Tris is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N8515C

UDP-3-O-acyl-GlcNAc disodium UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .

HY-N8060

Orotidine 5′-monophosphate Orotidine monophosphate; Orotidylic acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase .

HY-N7307

Pachybasin	Infection Quinones Monophenols Microorganisms Classification of Application Fields Anthraquinones Source classification Phenols Disease Research Fields	Bacterial
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

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E.coli metabolite

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