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Results for "

HNF-4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	GCGR (2) Histone Methyltransferase (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (2) Metabolic Disease (6)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Glucagon (1-29), bovine, human Maximum Cited Publications 9 Publications Verification Glucagon	GCGR	Metabolic Disease
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .

HNF4A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HNF4A Human Pre-designed siRNA Set A contains three designed siRNAs for HNF4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HNF4A Human Pre-designed siRNA Set A HNF4A Human Pre-designed siRNA Set A

HNF4G Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HNF4G Human Pre-designed siRNA Set A contains three designed siRNAs for HNF4G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HNF4G Human Pre-designed siRNA Set A HNF4G Human Pre-designed siRNA Set A

Glucagon (1-29), bovine, human hydrochloride Glucagon hydrochloride	GCGR	Metabolic Disease
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation .

BIM5078	Others	Metabolic Disease Cancer
BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes .

BI-6015 3 Publications Verification	Others	Metabolic Disease Cancer
BI-6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BI6015 represses insulin promoter activity through HNF4α antagonism. BI-6015 can be used for the research of cancer and diabetes .

Benfluorex hydrochloride 4 Publications Verification JP-992 hydrochloride	Others	Cardiovascular Disease Metabolic Disease
Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator.

Benfluorex JP-992	Others	Cardiovascular Disease Metabolic Disease
Benfluorex (JP-992) is a hepatic nuclear factor 4 alpha (HNF4α) activator.

DW14800	Histone Methyltransferase	Cancer
DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC₅₀ of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity .

Cat. No.	Product Name	Target	Research Area

Glucagon (1-29), bovine, human 5+ Cited Publications Glucagon	GCGR	Metabolic Disease
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .

Glucagon (1-29), bovine, human hydrochloride Glucagon hydrochloride	GCGR	Metabolic Disease
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation .

Cat. No.	Compare	Product Name	Species	Source

	HNF 4 alpha (HNF4A) Recombinant Protein,Human(C-His) FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF-14; TCF14	Human	HEK293
	HNF 4 alpha, a nuclear transcription factor, forms homodimers to bind DNA. It regulates gene expression, including hepatocyte nuclear factor 1 alpha, impacting hepatic genes. Its involvement extends to liver, kidney, and intestinal development. Mutations associate with autosomal dominant non-insulin-dependent diabetes mellitus type I. The gene exhibits biased expression in the duodenum (RPKM 37.7) and colon (RPKM 32.8), among other tissues. HNF 4 alpha (HNF4A) Recombinant Protein,Human (C-His) is the recombinant human-derived HNF 4 alpha, expressed by HEK293 , with C-10*His labeled tag. The total length of HNF 4 alpha (HNF4A) Recombinant Protein,Human (C-His) is 474 a.a., with molecular weight of ~70-80 kDa.


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