Search Result
Results for "
PEG4
" in MedChemExpress (MCE) Product Catalog:
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W099536
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Tetraoxyethylene glycol monododecyl ether
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Biochemical Assay Reagents
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Others
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PEG 4 lauryl ether can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-126496
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ADC Linker
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Cancer
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PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
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- HY-128968
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- HY-140388
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PROTAC Linkers
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Cancer
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PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133054
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PROTAC Linkers
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Cancer
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PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141322
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PROTAC Linkers
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Cancer
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PEG4-bis(phosphonic acid diethyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W190956
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Others
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Cancer
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(S,R,S)-AHPC-PEG4-acid is a synthetic PROTAC ligand that binds the E3 ligase ligand to the PEG4 arm, thereby enhancing PROTAC drug research and discovery .
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- HY-141053
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141068
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140610
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PROTAC Linkers
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Cancer
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Propargyl-PEG4-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140597
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PROTAC Linkers
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Cancer
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Propargyl-PEG4-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140589
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PROTAC Linkers
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Cancer
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Acid-PEG4-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140599
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PROTAC Linkers
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Cancer
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Propargyl-PEG4-S-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140598
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PROTAC Linkers
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Cancer
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Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140612
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PROTAC Linkers
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Cancer
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Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140131
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PROTAC Linkers
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Cancer
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Biotin-PEG4-PC-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-PC-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140877
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Fluorescent Dye
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Others
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Dde Biotin-PEG4-TAMRA-PEG4 Alkyne is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Dde Biotin-PEG4-TAMRA-PEG4 Alkyne contains Alkyne groups that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140114
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PROTAC Linkers
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Cancer
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Acid-PEG4-S-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135970
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ADC Linker
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Cancer
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Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Alkyne-PEG4-SS-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130973
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ADC Linker
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Cancer
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Mal-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140084
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PROTAC Linkers
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Cancer
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N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141124
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PROTAC Linkers
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Cancer
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NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140613
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PROTAC Linkers
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Cancer
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Boc-PEG4-sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130943
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ADC Linker
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Cancer
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Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130312
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PROTAC Linkers
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Cancer
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N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130967
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ADC Linker
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Cancer
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Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140582
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PROTAC Linkers
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Cancer
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N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140531
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PROTAC Linkers
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Cancer
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N-(Biotin-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140532
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PROTAC Linkers
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Cancer
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N-(Amino-PEG4)-N-Biotin-PEG4-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140259
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PROTAC Linkers
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Cancer
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N-(Boc-PEG4)-NH-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140255
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PROTAC Linkers
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Cancer
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N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141288
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PROTAC Linkers
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Cancer
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N-(Biotin-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140393
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PROTAC Linkers
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Cancer
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N-(Tos-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140786
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PROTAC Linkers
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Cancer
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Azido-PEG4-amido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141071
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-141036
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140519
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PROTAC Linkers
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Cancer
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N-(Azido-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-acid) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130435
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ADC Linker
PROTAC Linkers
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Cancer
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DBCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker) . DBCO-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-141078
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130422
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Tos-PEG4-Boc
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PROTAC Linkers
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Cancer
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Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM .
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- HY-140567
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PROTAC Linkers
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Cancer
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N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-126669
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ADC Linker
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Cancer
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Mal-PEG4-VA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate.
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- HY-141046
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-D2109
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Fluorescent Dye
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Others
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TAMRA-PEG4-COOH 是含有 4 个 PEG 单元的 TAMRA (HY-135640) 染料衍生物。TAMRA-PEG4-COOH 含有羧基，可以氨发生缩合反应形成共价键。
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- HY-140866
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PROTAC Linkers
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Cancer
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N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-145090
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PROTAC Linkers
ADC Linker
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Others
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DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140870
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PROTAC Linkers
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Cancer
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N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-D2106
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Fluorescent Dye
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Others
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TAMRA-PEG4-NHS 是含有 4 个 PEG 单元的 TAMRA (HY-135640) 染料衍生物。TAMRA-PEG4-NHS 含有 NHS 团，可与氨反应形成酯键。
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- HY-D2233
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Fluorescent Dye
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Others
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SiR-PEG4-alkyne is a near-infrared rhodamine fluorescent dye containing silica and alkynyl groups. SiR-PEG4-alkyne can be used in click chemistry .
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- HY-120397
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PROTAC Linkers
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Infection
Cancer
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Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers . Bis-propargyl-PEG4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-119429
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- HY-141030
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-126685
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- HY-151741
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ADC Linker
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Others
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Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates .
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- HY-141052
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PROTAC Linkers
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Cancer
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N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141032
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PROTAC Linkers
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Cancer
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N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-133492
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Drug-Linker Conjugates for ADC
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Cancer
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DBCO-PEG4-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO-PEG4. DBCO-PEG4-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-D2213
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- HY-117104
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ADC Linker
PROTAC Linkers
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Cancer
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Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141382
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PROTAC Linkers
ADC Linker
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Cancer
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Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W040214
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG4-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130457
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-141167
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ADC Linker
PROTAC Linkers
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Cancer
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TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-141069
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PROTAC Linkers
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Cancer
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N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-148057
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Drug-Linker Conjugates for ADC
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Cancer
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TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162) . TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-D2140
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Fluorescent Dye
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Others
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Cy3-PEG4-Alkyne 是含有 4 个 PEG 单元的 Cyanine 3 (Cy3) (HY-D0822) 染料衍生物。Cy3-PEG4-Alkyne 含有 Alkyne 基团，可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
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- HY-141067
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PROTAC Linkers
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Cancer
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N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140310
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ADC Linker
PROTAC Linkers
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Cancer
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TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-D2212
-
-
- HY-130346
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130591
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-116427
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-thiol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130387
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133433
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA . DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2214
-
|
|
Fluorescent Dye
|
Others
|
|
SiR-PEG4-BCN is a fluorescent dye. SiR-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140297
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxyrhodamine 110-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Carboxyrhodamine 110-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141075
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130161
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency . m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-141033
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cy5-PEG4-acid (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126668
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VC-PAB-DMEA is used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126672
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-Val-Cit-PAB is used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-156755
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Propargyl-PEG4-GGFG-DXd is a drug-linker conjugate for ADC. Propargyl-PEG4-GGFG-DXd contains a ADC linker and a DNA topoisomerase I inhibitor DXd (HY-13631D) .
|
-
- HY-141395
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156384
-
-
- HY-145383
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is an enrichment handle of cell surface glycoproteins for protein labeling .
|
-
- HY-111456
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-134723
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG . DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-114661
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
|
-
- HY-W008005
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-124123
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156387
-
|
|
PROTAC Linkers
|
Cancer
|
|
SCO-PEG4-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG4-COOH contains SCO and COOH that can be covalently combined with amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
|
-
- HY-126961
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130595
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-126959
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-133292
-
|
HS-PEG4-OH
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141031
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-135971
-
|
|
ADC Linker
|
Cancer
|
|
BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141089
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxyrhodamine 110-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138465
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-C4-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138527
-
|
|
PROTAC Linkers
|
Cancer
|
|
Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136314
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W046471
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG4-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-120666
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG4-Alkyne is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130990
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130417
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141159
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140953
-
|
|
PROTAC Linkers
|
Cancer
|
|
DSPE-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141363
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141332
-
|
|
PROTAC Linkers
|
Cancer
|
|
Lipoamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135153
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-120368
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130198
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130213
-
|
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141264
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140394
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141352
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138379
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138486
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096129
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cl-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138507
-
|
|
PROTAC Linkers
|
Cancer
|
|
Desthiobiotin-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-120678
-
|
|
PROTAC Linkers
|
Others
|
|
DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-113921
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-114670
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141286
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG4-methyltetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-methyltetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-141285
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG4-tetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133699
-
|
|
Ligands for E3 Ligase
|
Others
|
|
Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1) .
|
-
- HY-140156
-
|
Methylamino-PEG4-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141328
-
|
Thiol-PEG4-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130809
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138526
-
|
|
PROTAC Linkers
|
Cancer
|
|
Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-116025
-
|
|
PROTAC Linkers
|
Cancer
|
|
APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . APN-C3-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140287
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-C2-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C2-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140288
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-C3-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C3-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133229
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG4-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140955
-
|
|
PROTAC Linkers
|
Cancer
|
|
DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140037
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-?PEG4-?propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Mal-?PEG4-?propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140619
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DNP-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140058
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aminooxy-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140028
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140279
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-alcohol is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140272
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140045
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-methylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140047
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-sulfonic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140301
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-Desthiobiotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140308
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-triethoxysilane is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140278
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-PFP ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133439
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133399
-
|
|
PROTAC Linkers
|
Cancer
|
|
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136030
-
|
|
PROTAC Linkers
|
Cancer
|
|
APN-PEG4-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . APN-PEG4-PFP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133437
-
|
|
PROTAC Linkers
|
Cancer
|
|
BCN-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-alkyne is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-132050
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W096125
-
|
|
PROTAC Linkers
|
Cancer
|
|
Desthiobiotin-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Desthiobiotin-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138351
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-thioacetyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-thioacetyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140509
-
-
- HY-126516
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-120770
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140922
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140940
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133505
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133508
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-SSPy is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-156313
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156478
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156492
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-W039178
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). Hydroxy-PEG4-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-111997
-
|
HaloPROTAC 3
|
E3 Ligase Ligand-Linker Conjugates
|
|
|
VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and 16-atom-length linker. The connector of linker is Halogen group. VH285-PEG4-C4-Cl incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. VH285-PEG4-C4-Cl is a highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM. VH285-PEG4-C4-Cl is able to induce 90 % degradation of GFP-Halotag at 625 nM. VH285-PEG4-C4-Cl binds to VHL with an IC50 of 0.54 μM .
|
-
- HY-130086
-
|
|
ADC Linker
|
Cancer
|
|
Bis- PEG4- NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-124323
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130290
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-W040228
-
|
|
PROTAC Linkers
|
Cancer
|
|
BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-133009
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140410
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-aminooxy-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140548
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W108219
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-D2232
-
-
- HY-D2329
-
|
|
Fluorescent Dye
|
|
|
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-126884
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136131
-
|
|
ADC Linker
|
Cancer
|
|
NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH2-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136046
-
|
|
ADC Linker
|
Cancer
|
|
PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136049
-
|
|
ADC Linker
|
Cancer
|
|
APN-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136044
-
|
|
ADC Linker
|
Cancer
|
|
APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130939
-
|
|
ADC Linker
|
Cancer
|
|
APN-PEG4-Amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-Amine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136061
-
|
|
ADC Linker
|
Cancer
|
|
BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136067
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-HyNic is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136075
-
|
|
ADC Linker
|
Cancer
|
|
HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . HyNic-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140294
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-C2-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C2-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140295
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-C3-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C3-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140630
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-CH2-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140052
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140315
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-NH-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG4-NH-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140923
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-amide-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amide-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140069
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140926
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Propargyl-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG4)-biocytin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140307
-
|
|
PROTAC Linkers
|
Cancer
|
|
Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140291
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140073
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140924
-
|
|
PROTAC Linkers
|
Cancer
|
|
Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140931
-
|
|
PROTAC Linkers
|
Cancer
|
|
Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138753
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-sulfone-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138756
-
|
|
PROTAC Linkers
|
Cancer
|
|
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W040527
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-130230
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126998
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141402
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-Hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141179
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141183
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141188
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG4-TCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-122456
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140440
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140170
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141387
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141302
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxy-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140168
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxy-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141307
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140162
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135048
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130469
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130195
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130512
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W042579
-
|
|
PROTAC Linkers
|
Cancer
|
|
TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140748
-
|
|
PROTAC Linkers
|
Cancer
|
|
BnO-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140618
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140166
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140620
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140601
-
|
|
PROTAC Linkers
|
Cancer
|
|
Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140516
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140413
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-aminoxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140193
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140006
-
|
|
PROTAC Linkers
|
Cancer
|
|
Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140614
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140448
-
|
|
PROTAC Linkers
|
Cancer
|
|
Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140903
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141278
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140174
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141261
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133271
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141159A
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S)-TCO-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133316
-
|
|
PROTAC Linkers
|
Cancer
|
|
HO-PEG4-benzyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132008
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132017
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132024
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134704
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134720
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amine-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134722
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydrazide-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138346
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138352
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138372
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138382
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138421
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138422
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138423
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acryloyl-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138426
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-allyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138450
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138491
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetyl-PEG4-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141394
-
|
|
PROTAC Linkers
|
Cancer
|
|
Chloroacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W013522
-
|
|
PROTAC Linkers
|
Cancer
|
|
Me-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096073
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096074
-
|
|
PROTAC Linkers
|
Cancer
|
|
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132095
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132097
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138513
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096083
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ethyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096090
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190728
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126684
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a agent-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin SA, linked via Mal-PEG4-VC-PAB-DMEA-Seco.
|
-
- HY-136052
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-oxyamine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136053
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136056
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-oxyamine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136045
-
|
|
ADC Linker
|
Cancer
|
|
APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130925
-
|
|
ADC Linker
|
Cancer
|
|
BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133427
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-hydrazide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133430
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130927
-
|
|
ADC Linker
|
Cancer
|
|
BCN-PEG4-Ts is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-Ts is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130977
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136074
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136079
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG4-hydrazone-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130449
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130508
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-Ph-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-PEG4-azide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-138747
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-sulfone-PEG4-Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-141167B
-
|
|
ADC Linker
|
Cancer
|
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-140055
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology . Thalidomide-PEG4-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140074
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140263
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(m-PEG4) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2209
-
|
|
Fluorescent Dye
|
Others
|
|
SiR-PEG4-Me-tetrazine is a small molecule click chemical modified silyl rhodamine dye.
|
-
- HY-136288
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC) . Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140024
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-CH2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140139
-
|
|
ADC Linker
|
Cancer
|
|
PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130396
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-C2-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-135979
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-156323
-
|
|
ADC Linker
|
Cancer
|
|
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-126506
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-PFP ester is a nonclaevable ADC linker containing a Maleimide group, 4-unit PEG and a PFP ester.
|
-
- HY-140239
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140889
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140895
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140932
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-153172
-
|
|
Others
|
Others
|
|
Phenylbenzothiazole-PEG4-OH (compound 1) can treat spinal cord injury and promote spine formation .
|
-
- HY-144079
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-C4-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133426
-
|
Ald-benzyl-amide-PEG4-propargyl
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-157465
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MA-PEG4-VC-PAB-DMEA-duocarmycin DM is a drug-linker conjugate for ADC by using the anticancer antibiotic Duocarmycin DM (HY-130978), linked via MA-PEG4-vc-PAB-DMEA (HY-126668) .
|
-
- HY-140307A
-
|
|
PROTAC Linkers
|
Others
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140879
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140048
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-5-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-5-nitrophenyl carbonate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141013
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-O-amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Thalidomide-O-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133464
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-NHCO-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156300
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-140978
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040134
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140967
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-Amido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141103
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140423
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminoxy-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141350
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141347
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140626
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141311
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141341
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141012
-
-
- HY-130181
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135083
-
|
|
PROTAC Linkers
|
Cancer
|
|
BDP FL-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140223
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141249
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140391
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141113
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140377
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141303
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140286
-
|
|
PROTAC Linkers
|
Cancer
|
|
Sulfo DBCO-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140937
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-amido-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141001
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141304
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140258
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141279
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141088
-
|
|
PROTAC Linkers
|
Cancer
|
|
BDP FL-PEG4-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140016
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140600
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-Bis-(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133470
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140932A
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-hydrazide (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132064
-
|
|
PROTAC Linkers
|
Cancer
|
|
FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132067
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132079
-
|
|
PROTAC Linkers
|
Cancer
|
|
FmocNH-PEG4-t-butyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138481
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-methyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141119
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138758
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138755
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138752
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141167A
-
|
|
PROTAC Linkers
|
Cancer
|
|
(E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132109
-
|
|
PROTAC Linkers
|
Cancer
|
|
MS-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-153639
-
-
- HY-140633
-
|
N3-PEG4-CH2CH2CHO
|
PROTAC Linkers
|
Cancer
|
|
Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-C2-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130175
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-42640
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126505
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes .
|
-
- HY-136040
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130947
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-PEG4-SS-Py is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-Py is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133432
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-SS-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133466
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133435
-
|
|
ADC Linker
|
Cancer
|
|
Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136035
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136036
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136078
-
|
|
ADC Linker
|
Cancer
|
|
Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136260
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG4-Ahx-DM1 is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DBCO-PEG4-Ahx-DM1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140841
-
|
|
PROTAC Linkers
|
Cancer
|
|
APN-C3-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . APN-C3-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130524
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140141
-
|
|
PROTAC Linkers
|
Cancer
|
|
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133465
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-PEG4-Ph-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG4-Ph-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130695
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker used in the synthesis of PROTACs. N-(Amino-PEG5)-N-bis(PEG4-acid) contains an amino group with two terminal carboxylic acids .
|
-
- HY-141246
-
|
|
PROTAC Linkers
|
Cancer
|
|
1-Isothiocyanato-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141360
-
|
|
PROTAC Linkers
|
Cancer
|
|
(2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141359
-
|
|
PROTAC Linkers
|
Cancer
|
|
(2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134742
-
|
|
PROTAC Linkers
|
Cancer
|
|
3-Aminophenol-PEG4-methyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141159B
-
-
- HY-126883
-
-
- HY-130414
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135961
-
|
|
ADC Linker
|
Cancer
|
|
PTAD-PEG4-amine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-135964
-
|
|
ADC Linker
|
Cancer
|
|
(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136048
-
|
|
ADC Linker
|
Cancer
|
|
Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136127
-
|
|
ADC Linker
|
Cancer
|
|
ALD-PEG4-OPFP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-138488
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W096079
-
|
|
ADC Linker
|
Cancer
|
|
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-130090
-
|
|
ADC Linker
|
Cancer
|
|
NHPI-PEG4-C2-Pfp ester is used as a linker for antibody-drug conjugates (ADC).
|
-
- HY-140578
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Me-N-bis-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140587
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Benzyl-N-bis-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130197
-
|
|
PROTAC Linkers
|
Cancer
|
|
Lipoamido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D1070
-
|
|
DNA Stain
|
Others
|
|
DBCO-PEG4-TAMRA is a PEG-based TAMRA dye and contains a DBCO group, which enables Click Chemistry. The TAMRA dye is a dye widely used in oligonucleotide labeling and automated DNA sequencing applications. DBCO-PEG4-TAMRA is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138692
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-138715
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Benzyl-PEG4-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-136261
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DM1-(PEG)4-DBCO is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DM1-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140023
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140063
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2-methyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140309
-
|
|
ADC Linker
|
Cancer
|
|
Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Gly-Gly-Gly-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W039197
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG4-mono-methyl ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140507
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-CH2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W096111A
-
|
|
PROTAC Linkers
|
Cancer
|
|
Trt-PEG4-C2-acid (hydrate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W021787
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-124386
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) .
|
-
- HY-156308
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-130527
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140580
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis(m-PEG4)-N-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140579
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140250
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tri(Amino-PEG4-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140528
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140540
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141132
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141002
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-Mal-Lysine-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141126
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140380
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-aminoxy-Boc-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140417
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140135
-
|
|
PROTAC Linkers
|
Cancer
|
|
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134715
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-N-amido-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143821
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138752A
-
|
|
PROTAC Linkers
|
Cancer
|
|
S-acetyl-PEG4-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126950
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Aminooxy-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-22340
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG4-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140765
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140842
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-nitrile is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140777
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140814
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140351
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG4-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133438
-
|
|
PROTAC Linkers
|
Cancer
|
|
BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-133455
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzaldehyde-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzaldehyde-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-138472
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-THP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-132096
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-acyl chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-138525
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130654
-
|
VH032-C2-PEG4-N3
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-C2-PEG4-N3 can be used in the synthesis of vRucaparib-TP4 (HY-130647). vRucaparib-TP4 a highly potent PARP1 degrader with a half-maximal degrading concentration (DC50) of 82 nM . (S,R,S)-AHPC-C2-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141147
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-133436
-
|
|
ADC Linker
|
Cancer
|
|
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-aminooxy-amide-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133576
-
|
|
ADC Linker
|
Cancer
|
|
Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Cyclooctyne-O-amido-PEG4-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130653
-
|
|
PROTAC Linkers
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130436
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140887
-
|
|
PROTAC Linkers
|
Cancer
|
|
1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 1,1,1-Trifluoroethyl-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133462
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-156726
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-amino-PEG4-C4-Cl (Intermediate 4d) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-amino-PEG4-C4-Cl can be used in the synthesis of PROTAC .
|
-
- HY-129773
-
|
|
PROTAC Linkers
|
Cancer
|
|
Phthalimide-PEG4-PDM-OTBS is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG4-PDM-OTBS can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-129774
-
|
|
PROTAC Linkers
|
Cancer
|
|
Phthalimide-PEG4-MPDM-OH is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG4-MPDM-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-W190943
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH . Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130481
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib (HY-10997)-based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells . Propargyl-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140910
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-42617
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140438
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138530
-
|
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG4-amide-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-145066
-
|
|
ADC Linker
|
Cancer
|
|
Gly-Gly-Gly-PEG4-azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140243
-
|
|
PROTAC Linkers
|
Cancer
|
|
111-Trifluoroethyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190966
-
|
|
PROTAC Linkers
|
Others
|
|
t-Boc-Aminooxy-PEG4-t-butyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-149039
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Amine-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a organic compounds, acts as a linker used to synthesize multifunctional molecules.
|
-
- HY-135306
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cl-C6-PEG4-C3-COOH is a PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs) .
|
-
- HY-120781
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-thiourea-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Fluorescein-thiourea-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130389
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG4-O-C1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140594
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . m-PEG3-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140608
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG3-Sulfone-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140591
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-136103
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Propionic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136098
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-acetic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138785
-
-
- HY-138785A
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-5-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology .
|
-
- HY-117041
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-CH2-aldehyde is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-133057
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-CH2-alcohol is PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130473
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130478
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-42620
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140498
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141245
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-C2-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130477
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W019796
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cbz-NH-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140402
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140465
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NMe-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141242
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141122
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140403
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133339
-
|
|
PROTAC Linkers
|
Cancer
|
|
H2N-PEG4-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-42619
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134675
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG4-C1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134690
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propanol-PEG4-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138408
-
|
|
PROTAC Linkers
|
Cancer
|
|
BocNH-PEG4-CH2CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138446
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-C2-SH hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W800630
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126691
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. DBCO-PEG4-VC-PAB-DMEA-PNU-159682 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140149
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-160981
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB .
|
-
- HY-130097
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-140573
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG4-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140262
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-Tri-(m-PEG4-ethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140510
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Methyl-N-(t-Boc)-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141252
-
|
|
PROTAC Linkers
|
Cancer
|
|
N,N-Diethanol amine-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140250A
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tri(Amino-PEG4-amide)-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130819
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-THP is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) .
|
-
- HY-138774
-
-
- HY-140433
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140915
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-123609
-
|
|
PROTAC Linkers
|
Cancer
|
|
Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Pyrene-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140919
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-biocytin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140817
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140916
-
|
|
PROTAC Linkers
|
Cancer
|
|
Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140836
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-138388
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-formylhydrazine-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-formylhydrazine-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-139107
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130390
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141015
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology . Pomalidomide-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130108
-
|
|
ADC Linker
|
Cancer
|
|
N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-Pfp ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130109
-
|
|
ADC Linker
|
Cancer
|
|
N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-136058
-
|
|
ADC Linker
|
Cancer
|
|
N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG4-amido-Lys(Fmoc)-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130470
-
|
|
PROTAC Linkers
|
Cancer
|
|
Chloroacetamido-PEG4-C2-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-22335
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-C2-amine is a PEG-based (4 units) PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-141404
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140478
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-amido-PEG4-C3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133545
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Ph-CONH-PEG4- NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-126687
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682 .
|
-
- HY-141049
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-methyl-N'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-132161
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a Camptothecin-linker compound extracted from patent WO2019195665A1, example 4-1. MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a agent-linker conjugate for antibody-drug conjugate (ADC) .
|
-
- HY-D2211
-
|
|
Fluorescent Dye
|
Others
|
|
SiR-PEG4-NHS ester is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 652/674 nm
|
-
- HY-42618
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140379
-
|
|
PROTAC Linkers
|
Cancer
|
|
1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140445
-
|
|
PROTAC Linkers
|
Cancer
|
|
1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141247
-
|
|
PROTAC Linkers
|
Cancer
|
|
1,1,1-Trifluoroethyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141006
-
|
|
PROTAC Linkers
|
Cancer
|
|
3,4-Dibromo-Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132163
-
|
|
ADC Linker
|
Cancer
|
|
MP-PEG4-VK(Boc)G-OSu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130293
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130968
-
|
|
ADC Linker
|
Cancer
|
|
Amino-PEG4-bis-PEG3-propargyl is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130971
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140558
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140572
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140583
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140241
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH2-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130520
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-130536
-
|
|
PROTAC Linkers
|
Cancer
|
|
Br-PEG4-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141284
-
|
|
ADC Linker
|
Cancer
|
|
Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136134
-
|
|
ADC Linker
|
Cancer
|
|
SS-bis-amino-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W004816
-
|
PROTAC Linker 16
|
PROTAC Linkers
|
Cancer
|
|
Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W025896
-
|
PROTAC Linker 12
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4 (PROTAC Linker 12) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141155
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141014
-
-
- HY-141010
-
-
- HY-141011
-
|
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
|
Thalidomide-O-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Thalidomide-O-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140858
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-4-nitrophenyl carbonate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140012
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-beta-D-glucose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140917
-
|
|
PROTAC Linkers
|
Cancer
|
|
Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-158382
-
-
- HY-140420
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140530
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-N-bis(PEG4-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130491
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141309
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-(CH2)6-Phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141314
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-C6-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141125
-
|
|
PROTAC Linkers
|
Cancer
|
|
NHS-PEG4-(m-PEG12)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138370
-
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PROTAC Linkers
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Cancer
|
|
Boc-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156166
-
-
- HY-140844
-
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E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
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|
Thalidomide-O-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Thalidomide-O-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130940
-
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ADC Linker
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Cancer
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|
PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130953
-
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ADC Linker
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Cancer
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|
Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130970
-
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ADC Linker
|
Cancer
|
|
Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140575
-
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PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141133
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141135
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-tetra-Ac-beta-D-galactose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141127
-
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PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130091
-
|
|
ADC Linker
|
Cancer
|
|
NHPI-PEG4-C2-NHS ester, example 40 (WO2014185985A1), is used as a linker for antibody-drug conjugates (ADC) .
|
-
- HY-42774
-
|
1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141148
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
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|
7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-141010A
-
-
- HY-W040132
-
|
|
PROTAC Linkers
ADC Linker
|
Cancer
|
|
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC . Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC) .
|
-
- HY-141074
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-hydroxypropyl-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141054
-
|
|
PROTAC Linkers
|
Cancer
|
|
N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141042
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-(N,N'-carboxyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130315
-
-
- HY-23167
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR .
|
-
- HY-138790
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology .
|
-
- HY-140584
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130964B
-
-
- HY-140602
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141154
-
-
- HY-140143
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140145
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141149
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-PEG4-Ala-Ala-Asn-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136157
-
|
|
ADC Linker
|
Cancer
|
|
Py-ds-dmBut-amido-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140537
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Boc-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140261
-
|
|
PROTAC Linkers
|
Cancer
|
|
NH-bis(PEG4-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141808
-
|
|
Others
|
Cancer
|
|
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker can be used for antibody-siRNA conjugate synthesis .
|
-
- HY-140568
-
|
N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester
|
PROTAC Linkers
|
Cancer
|
|
N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130974
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-134693
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-C1-PEG4-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-C1-PEG4-C3-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140242
-
|
|
ADC Linker
|
Cancer
|
|
NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a cleavable 28 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-128803
-
|
PROTAC Linker 7
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W110146
-
-
- HY-141050
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-PEG3-N'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-PEG3-N'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140556
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG4-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130543
-
|
|
PROTAC Linkers
|
Cancer
|
|
111-Trifluoroethyl-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 1,1,1-Trifluoroethyl-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140523
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141010B
-
-
- HY-130101
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-138380
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-131998
-
-
- HY-141000
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-Lys(TFA)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140997
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126668A
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA TFA is a degradable ADC linker containing a maleimide group and can be used to synthesize antibody conjugate active molecules (ADCs) .
|
-
- HY-140928
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138859
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-amino-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .
|
-
- HY-138859A
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .
|
-
- HY-148426
-
-
- HY-140874
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140846
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Fmoc-N'-(azido-PEG4)-L-Lysine is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141251
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Hydroxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140254
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140446
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141047
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-(N,N'-PEG4-NHS ester)-Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140809
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-(CH2)3OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-(CH2)3OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140854
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-(CH2)3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-(CH2)3-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140914
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Amide-C6-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140604
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W008352
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143208
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt has inhibitory activity against pre-miR-21 RNA. HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt has the potential for the research of neoplastic disease such as cancer and especially cancers expressing miR-21 (extracted from patent WO2021087084A1, compound 25) .
|
-
- HY-140095
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-400676
-
|
|
ADC Linker
|
Cancer
|
|
NH2-PEG4-GGFG-CH2-O-CH2-Cbz is a reactant for the synthesis of ADC linker and is used to synthesize Antibody-Drug Conjugates (ADCs) .
|
-
- HY-141035
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(PEG2-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140157
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Me-N-bis(PEG4-C2-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140998
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140999
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG4-Lys(t-Boc)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136084
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-151833
-
|
|
ADC Linker
|
Others
|
|
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140518
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG4-acid) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140525
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140592
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-S-PEG4-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140546
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141091
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-136155
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140416
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130397
-
|
|
PROTAC Linkers
|
Cancer
|
|
Pyrene-amido-PEG4-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140191
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG4-(CH2)3CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130861
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-NH-PEG4-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141038
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-160069
-
|
|
PROTAC Linkers
|
Others
|
|
Fmoc-Gly-Gly-Gly-NH-PEG4-C2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
|
-
- HY-140133
-
|
|
ADC Linker
|
Cancer
|
|
PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-128834
-
|
PROTAC Linker 20
|
PROTAC Linkers
|
Cancer
|
|
N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . N3-PEG4-C2-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-124780
-
|
|
PROTAC Linkers
|
Others
|
|
HOOCCH2O-PEG4-CH2COOH, compound 5, is a symmetric PEG linker, used for the synthesis of the first class of Homo-PROTAC .
|
-
- HY-126515
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154802
-
|
|
ADC Linker
|
Cancer
|
|
TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-400677
-
|
|
ADC Linker
|
Cancer
|
|
NH2-PEG4-GGFG-NH-CH2-O-CH2COOH is a reactant for the synthesis of ADC linkers and is used to synthesize Antibody-Drug Conjugates (ADCs) .
|
-
- HY-W000434
-
|
Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141063
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141076
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(PEG3-Mal)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141056
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(amino-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141073
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141070
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140847
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl/ether and PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-126677
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC). Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-130598
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs N-(Azido-PEG3)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-112496
-
|
PROTAC Linker 4
|
PROTAC Linkers
|
Cancer
|
|
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs) .
|
-
- HY-141064
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(azide-PEG3)-N'-(m-PEG4)-Benzothiazole Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140565
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140563
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140581
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140867
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140869
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140560
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141041
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141045
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-157407
-
-
- HY-136090
-
|
|
ADC Linker
|
Cancer
|
|
Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-134591
-
-
- HY-140828
-
|
13-Azido-2,5,8,11-tetraoxatridecane
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . m-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140566
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Azido-PEG4-N-Boc-N-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140921
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-112599B
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs..
|
-
- HY-130969
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130820
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) .
|
-
- HY-130821
-
|
|
PROTAC Linkers
|
Cancer
|
|
THP-PEG4-Pyrrolidine(N-Me)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) .
|
-
- HY-141066
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-122710
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-O-amido-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology .
|
-
- HY-138857
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-NH-amido-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology .
|
-
- HY-138857A
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology .
|
-
- HY-122710A
-
-
- HY-141040
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-methyl-N'-methyl-O-(m-PEG4)-O'-(acid-PEG5)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141048
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D2117
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130946
-
|
|
ADC Linker
|
Cancer
|
|
NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141065
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156810
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize active antibody conjugation molecules (ADC) .
|
-
- HY-141039
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-3,3-Dimethyl-3H-indole-N'-(acid-PEG3)-benzothiazole is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-103601
-
|
VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4
|
E3 Ligase Ligand-Linker Conjugates
|
Others
|
|
(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-103604
-
|
VH032-PEG4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 4 hydrochloride; E3 ligase Ligand-Linker Conjugates 7
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
|
-
- HY-21930
-
|
Cereblon Ligand -Linker Conjugates 1; E3 Ligase Ligand-Linker Conjugates 1
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
|
-
- HY-103604A
-
|
VH032-PEG4-NH2; VHL Ligand-Linker Conjugates 4 ; E3 ligase Ligand-Linker Conjugates 7 Free Base
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
|
-
- HY-125541
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140821
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-41549
-
|
Cereblon Ligand-Linker Conjugates 9; E3 Ligase Ligand-Linker Conjugates 2
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
|
-
- HY-112599
-
|
Cereblon Ligand-Linker Conjugates 8; E3 Ligase Ligand-Linker Conjugates 22
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
|
-
- HY-128832
-
|
MDM2 Ligand-Linker Conjugates 1; E3 ligase Ligand-Linker Conjugates 48
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology. Nutlin-C1-amido-PEG4-C2-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-A0023AS2
-
-
- HY-139859
-
|
|
ADC Linker
|
Cancer
|
|
APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2234
-
|
|
Fluorescent Dye
|
Others
|
|
SiR-PEG3-TCO is a near-infrared rhodamine fluorescent dye containing silica. SiR-PEG4-alkyne can be used in click chemistry .
|
-
- HY-148459
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate .
|
-
- HY-140820
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151649
-
|
|
ADC Linker
|
Others
|
|
Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an alkyne group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical .
|
-
- HY-151670
-
|
|
ADC Linker
|
Others
|
|
Biotin-PEG(4)-SS-Azide is a click chemistry reagent containing an azide group. Biotin-PEG(4)-SS-Azide can be used for the research of various biochemical .
|
-
- HY-151726
-
|
|
ADC Linker
|
Others
|
|
Azido-PEG(4)-Val-Cit-PAB-PNP is a click chemistry reagent containing an azide group.
|
-
- HY-141210
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-41541
-
|
Tos-PEG4
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2109
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG4-COOH 是含有 4 个 PEG 单元的 TAMRA (HY-135640) 染料衍生物。TAMRA-PEG4-COOH 含有羧基，可以氨发生缩合反应形成共价键。
|
-
- HY-D2106
-
-
- HY-D2233
-
|
|
Fluorescent Dyes/Probes
|
|
SiR-PEG4-alkyne is a near-infrared rhodamine fluorescent dye containing silica and alkynyl groups. SiR-PEG4-alkyne can be used in click chemistry .
|
-
- HY-D2213
-
-
- HY-D2140
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG4-Alkyne 是含有 4 个 PEG 单元的 Cyanine 3 (Cy3) (HY-D0822) 染料衍生物。Cy3-PEG4-Alkyne 含有 Alkyne 基团，可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
|
-
- HY-D2212
-
-
- HY-D2214
-
|
|
Fluorescent Dyes/Probes
|
|
SiR-PEG4-BCN is a fluorescent dye. SiR-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-145383
-
|
|
Protein Labeling
|
|
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is an enrichment handle of cell surface glycoproteins for protein labeling .
|
-
- HY-D2232
-
-
- HY-D2329
-
|
|
Fluorescent Dyes/Probes
|
|
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-D2209
-
-
- HY-D2211
-
|
|
Fluorescent Dyes/Probes
|
|
SiR-PEG4-NHS ester is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 652/674 nm
|
-
- HY-141066
-
|
|
Fluorescent Dyes/Probes
|
|
N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D2117
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2234
-
|
|
Fluorescent Dyes/Probes
|
|
SiR-PEG3-TCO is a near-infrared rhodamine fluorescent dye containing silica. SiR-PEG4-alkyne can be used in click chemistry .
|
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-A0023AS2
-
|
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-141053
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141068
-
|
|
|
Azide
|
|
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140610
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG4-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140597
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140599
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-S-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140598
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140612
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140131
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Biotin-PEG4-PC-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-PC-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140877
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Dde Biotin-PEG4-TAMRA-PEG4 Alkyne is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Dde Biotin-PEG4-TAMRA-PEG4 Alkyne contains Alkyne groups that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-135970
-
|
|
|
ADC Synthesis
Alkynes
|
|
Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Alkyne-PEG4-SS-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130973
-
|
|
|
Alkynes
ADC Synthesis
|
|
Mal-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140084
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130943
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130312
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130967
-
|
|
|
Alkynes
ADC Synthesis
|
|
Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140582
-
|
|
|
DBCO
PROTAC Synthesis
|
|
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140786
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG4-amido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-141071
-
|
|
|
DBCO
PROTAC Synthesis
|
|
N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140519
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-acid) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130435
-
|
|
|
DBCO
PROTAC Synthesis
ADC Synthesis
|
|
DBCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker) . DBCO-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141078
-
|
|
|
Azide
|
|
N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140567
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140866
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-145090
-
|
|
|
DBCO
PROTAC Synthesis
ADC Synthesis
|
|
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140870
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-D2233
-
|
|
|
Alkynes
|
|
SiR-PEG4-alkyne is a near-infrared rhodamine fluorescent dye containing silica and alkynyl groups. SiR-PEG4-alkyne can be used in click chemistry .
|
-
- HY-120397
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers . Bis-propargyl-PEG4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141030
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151741
-
|
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
|
Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates .
|
-
- HY-141052
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141032
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133492
-
|
|
|
DBCO
|
|
DBCO-PEG4-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO-PEG4. DBCO-PEG4-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141167
-
|
|
|
TCO
PROTAC Synthesis
ADC Synthesis
|
|
TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148057
-
|
|
|
TCO
ADC Synthesis
|
|
TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162) . TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-D2140
-
-
- HY-141067
-
|
|
|
Azide
|
|
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140310
-
|
|
|
ADC Synthesis
PROTAC Synthesis
TCO
DBCO
|
|
TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-130346
-
|
|
|
DBCO
PROTAC Synthesis
ADC Synthesis
|
|
DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130591
-
|
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
|
Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-116427
-
|
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
|
Propargyl-PEG4-thiol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130387
-
|
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133433
-
|
|
|
DBCO
|
|
DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA . DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2214
-
|
|
|
BCN
|
|
SiR-PEG4-BCN is a fluorescent dye. SiR-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140297
-
|
|
|
PROTAC Synthesis
DBCO
|
|
Carboxyrhodamine 110-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Carboxyrhodamine 110-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-111456
-
|
|
|
PROTAC Synthesis
DBCO
ADC Synthesis
|
|
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-134723
-
|
|
|
DBCO
|
|
DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG . DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141031
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-135971
-
|
|
|
BCN
ADC Synthesis
|
|
BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141089
-
|
|
|
Alkynes
|
|
Carboxyrhodamine 110-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136314
-
|
|
|
DBCO
|
|
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-120666
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
TAMRA-PEG4-Alkyne is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-130990
-
|
|
|
DBCO
|
|
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-141159
-
|
|
|
TCO
|
|
TCO-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
- HY-141264
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-120678
-
|
|
|
DBCO
|
|
DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-113921
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-114670
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-141286
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
TAMRA-PEG4-methyltetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-methyltetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-141285
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
TAMRA-PEG4-tetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130809
-
|
|
|
DBCO
|
|
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-116025
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . APN-C3-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140287
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-C2-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C2-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140288
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-C3-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C3-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133229
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG4-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140955
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140037
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Mal-?PEG4-?propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Mal-?PEG4-?propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140619
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DNP-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140058
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aminooxy-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140028
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140279
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-alcohol is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140272
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140045
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-methylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140047
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-sulfonic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140301
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-Desthiobiotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140308
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-triethoxysilane is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140278
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-PFP ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133439
-
|
|
|
PROTAC Synthesis
BCN
|
|
BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133399
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-133437
-
|
|
|
Alkynes
BCN
PROTAC Synthesis
|
|
BCN-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-alkyne is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-132050
-
|
|
|
Azide
PROTAC Synthesis
Alkynes
|
|
Azido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-W096125
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Desthiobiotin-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Desthiobiotin-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-138351
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-thioacetyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-thioacetyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-126516
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-120770
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140922
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140940
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133505
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133508
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-SSPy is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-156313
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-156478
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-156492
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-133009
-
|
|
|
BCN
|
|
endo-BCN-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
- HY-D2232
-
|
|
|
Azide
|
|
SiR-PEG4-azide is a near infrared silica-containing Rhodamine fluorescent dyes .
|
- HY-126884
-
|
|
|
ADC Synthesis
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-136131
-
|
|
|
ADC Synthesis
DBCO
|
|
NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH2-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-136046
-
|
|
|
Alkynes
ADC Synthesis
|
|
PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-136049
-
|
|
|
DBCO
ADC Synthesis
|
|
APN-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-136044
-
|
|
|
ADC Synthesis
BCN
|
|
APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-136061
-
|
|
|
BCN
ADC Synthesis
|
|
BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-136067
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-HyNic is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-136075
-
|
|
|
ADC Synthesis
Alkynes
|
|
HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . HyNic-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140294
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-C2-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C2-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140295
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-C3-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-C3-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140052
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-aminooxy-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140315
-
|
|
|
DBCO
PROTAC Synthesis
|
|
m-PEG4-NH-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG4-NH-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140923
-
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|
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Alkynes
PROTAC Synthesis
|
|
Biotin-PEG4-amide-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amide-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140069
-
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BCN
PROTAC Synthesis
|
|
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140926
-
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|
|
PROTAC Synthesis
Alkynes
|
|
N-(Propargyl-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG4)-biocytin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140307
-
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|
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DBCO
PROTAC Synthesis
|
|
Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140291
-
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|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140073
-
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|
|
BCN
PROTAC Synthesis
|
|
endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140924
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140931
-
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|
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DBCO
PROTAC Synthesis
|
|
Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-138753
-
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|
|
PROTAC Synthesis
DBCO
|
|
Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-sulfone-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-138756
-
|
|
|
PROTAC Synthesis
DBCO
|
|
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-141179
-
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|
TCO
|
|
TCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
- HY-141183
-
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|
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TCO
|
|
TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
- HY-141188
-
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|
|
TCO
|
|
TCO-PEG4-TCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
- HY-141278
-
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|
|
Tetrazine
|
|
Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141261
-
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|
|
Tetrazine
|
|
Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141159A
-
|
|
|
TCO
|
|
(S)-TCO-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-136052
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-oxyamine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136053
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136056
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-oxyamine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136045
-
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|
|
Tetrazine
ADC Synthesis
|
|
APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130925
-
|
|
|
BCN
ADC Synthesis
|
|
BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133427
-
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|
|
Alkynes
ADC Synthesis
|
|
Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-hydrazide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-133430
-
|
|
|
DBCO
Alkynes
ADC Synthesis
|
|
DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-130927
-
|
|
|
ADC Synthesis
BCN
|
|
BCN-PEG4-Ts is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-Ts is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-130977
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136074
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136079
-
|
|
|
DBCO
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG4-hydrazone-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130508
-
|
|
|
Tetrazine
Azide
PROTAC Synthesis
|
|
Methyltetrazine-Ph-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-PEG4-azide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-138747
-
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|
|
Tetrazine
PROTAC Synthesis
|
|
Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-sulfone-PEG4-Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-141167B
-
|
|
|
TCO
|
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-140055
-
|
|
|
Alkynes
|
|
Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology . Thalidomide-PEG4-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140074
-
|
|
|
BCN
|
|
endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
- HY-D2209
-
|
|
|
Tetrazine
|
|
SiR-PEG4-Me-tetrazine is a small molecule click chemical modified silyl rhodamine dye.
|
- HY-136288
-
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|
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Azide
|
|
Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC) . Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-140024
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-CH2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140139
-
|
|
|
Alkynes
ADC Synthesis
|
|
PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-130396
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-C2-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-135979
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-156323
-
|
|
|
BCN
|
|
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-133426
-
|
Ald-benzyl-amide-PEG4-propargyl
|
|
Alkynes
ADC Synthesis
|
|
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140307A
-
|
|
|
DBCO
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140879
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-N-Amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140048
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG4-5-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-5-nitrophenyl carbonate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-141013
-
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|
|
PROTAC Synthesis
Alkynes
|
|
Thalidomide-O-amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Thalidomide-O-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-133464
-
|
|
|
Tetrazine
Alkynes
PROTAC Synthesis
|
|
Tetrazine-Ph-NHCO-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-156300
-
|
|
|
Tetrazine
|
|
Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-141350
-
|
|
|
Alkynes
|
|
S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141249
-
|
|
|
Azide
|
|
Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141279
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141088
-
|
|
|
TCO
|
|
BDP FL-PEG4-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141167A
-
|
|
|
PROTAC Synthesis
TCO
|
|
(E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-140633
-
|
N3-PEG4-CH2CH2CHO
|
|
PROTAC Synthesis
Azide
|
|
Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-C2-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-136040
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130947
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Tetrazine-PEG4-SS-Py is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-Py is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133432
-
|
|
|
TCO
ADC Synthesis
DBCO
|
|
DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-SS-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-133466
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133435
-
|
|
|
ADC Synthesis
Alkynes
|
|
Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-136035
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136036
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136078
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136260
-
|
|
|
DBCO
|
|
DBCO-PEG4-Ahx-DM1 is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DBCO-PEG4-Ahx-DM1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140841
-
|
|
|
Azide
PROTAC Synthesis
|
|
APN-C3-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . APN-C3-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-140141
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133465
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Tetrazine-Ph-PEG4-Ph-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG4-Ph-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-141360
-
|
|
|
Alkynes
|
|
(2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141159B
-
|
|
|
TCO
|
|
(S,E)-TCO2-PEG4-COOH contains TCO groups, and can undergo specific "click" reactions with tetrazine groups .
|
- HY-W096079
-
|
|
|
BCN
|
|
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-130197
-
|
|
|
Azide
PROTAC Synthesis
|
|
Lipoamido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-D1070
-
|
|
|
DBCO
|
|
DBCO-PEG4-TAMRA is a PEG-based TAMRA dye and contains a DBCO group, which enables Click Chemistry. The TAMRA dye is a dye widely used in oligonucleotide labeling and automated DNA sequencing applications. DBCO-PEG4-TAMRA is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-138692
-
|
|
|
Azide
PROTAC Synthesis
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Azido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-138715
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PROTAC Synthesis
Azide
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Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Benzyl-PEG4-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-136261
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DBCO
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DM1-(PEG)4-DBCO is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DM1-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140023
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Alkynes
PROTAC Synthesis
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Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140063
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Alkynes
PROTAC Synthesis
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Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2-methyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140309
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DBCO
ADC Synthesis
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Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Gly-Gly-Gly-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-124386
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ADC Synthesis
DBCO
PROTAC Synthesis
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DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) .
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- HY-156308
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Tetrazine
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Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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- HY-141132
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Alkynes
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Propargyl-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141126
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Azide
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Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126950
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PROTAC Synthesis
Azide
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Aminooxy-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Aminooxy-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-22340
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PROTAC Synthesis
Azide
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Azido-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG4-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140765
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PROTAC Synthesis
Azide
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Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140842
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Azide
PROTAC Synthesis
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Azido-PEG4-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-nitrile is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140777
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PROTAC Synthesis
Azide
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Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140814
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Azide
PROTAC Synthesis
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Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140351
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Azide
PROTAC Synthesis
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Azide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG4-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-133438
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PROTAC Synthesis
BCN
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BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-133455
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PROTAC Synthesis
Azide
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Benzaldehyde-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzaldehyde-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-138472
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PROTAC Synthesis
Azide
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Azido-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-THP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-132096
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Azide
PROTAC Synthesis
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Azido-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-acyl chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-138525
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PROTAC Synthesis
Azide
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Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130654
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VH032-C2-PEG4-N3
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Azide
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(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-C2-PEG4-N3 can be used in the synthesis of vRucaparib-TP4 (HY-130647). vRucaparib-TP4 a highly potent PARP1 degrader with a half-maximal degrading concentration (DC50) of 82 nM . (S,R,S)-AHPC-C2-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-133436
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ADC Synthesis
Alkynes
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Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-aminooxy-amide-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130653
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ADC Synthesis
Azide
PROTAC Synthesis
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Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140887
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PROTAC Synthesis
Alkynes
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1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 1,1,1-Trifluoroethyl-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-133462
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PROTAC Synthesis
Tetrazine
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Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-W190943
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Azide
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Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH . Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130481
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PROTAC Synthesis
Alkynes
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Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib (HY-10997)-based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells . Propargyl-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140910
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PROTAC Synthesis
Azide
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Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-145066
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ADC Synthesis
Azide
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Gly-Gly-Gly-PEG4-azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-120781
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PROTAC Synthesis
Azide
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Fluorescein-thiourea-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Fluorescein-thiourea-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130389
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Alkynes
PROTAC Synthesis
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Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG4-O-C1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140594
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Alkynes
PROTAC Synthesis
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m-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . m-PEG3-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140608
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PROTAC Synthesis
Alkynes
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m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG3-Sulfone-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140591
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PROTAC Synthesis
Azide
Alkynes
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Azido-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-136103
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DBCO
ADC Synthesis
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DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Propionic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-136098
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DBCO
ADC Synthesis
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DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-acetic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-126691
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DBCO
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DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. DBCO-PEG4-VC-PAB-DMEA-PNU-159682 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140149
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Azide
PROTAC Synthesis
ADC Synthesis
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Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140433
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PROTAC Synthesis
Azide
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Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-Aminooxy-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140915
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PROTAC Synthesis
Azide
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Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-123609
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PROTAC Synthesis
Azide
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Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Pyrene-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140919
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Azide
PROTAC Synthesis
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N-(Azido-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-biocytin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140817
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PROTAC Synthesis
Azide
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Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140916
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Azide
PROTAC Synthesis
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Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140836
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PROTAC Synthesis
Azide
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Boc-NH-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-138388
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Azide
PROTAC Synthesis
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Azido-PEG4-formylhydrazine-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-formylhydrazine-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-139107
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Azide
ADC Synthesis
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Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130390
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Alkynes
PROTAC Synthesis
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Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141015
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Azide
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Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology . Pomalidomide-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130108
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Azide
ADC Synthesis
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N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-Pfp ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130109
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ADC Synthesis
Azide
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N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-136058
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Azide
ADC Synthesis
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N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG4-amido-Lys(Fmoc)-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141049
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Alkynes
PROTAC Synthesis
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N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-methyl-N'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-42618
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ADC Synthesis
PROTAC Synthesis
Azide
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Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130293
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ADC Synthesis
PROTAC Synthesis
Alkynes
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Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130968
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ADC Synthesis
Alkynes
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Amino-PEG4-bis-PEG3-propargyl is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130971
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ADC Synthesis
DBCO
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Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-141284
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ADC Synthesis
Tetrazine
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Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-141155
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BCN
ADC Synthesis
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endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-141011
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PROTAC Synthesis
Azide
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Thalidomide-O-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Thalidomide-O-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140858
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PROTAC Synthesis
Azide
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Azido-PEG4-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-4-nitrophenyl carbonate is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140012
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Azide
PROTAC Synthesis
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Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-beta-D-glucose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140917
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Azide
PROTAC Synthesis
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Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140844
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Azide
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Thalidomide-O-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Thalidomide-O-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130940
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ADC Synthesis
Azide
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PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130953
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Tetrazine
ADC Synthesis
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Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130970
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ADC Synthesis
Tetrazine
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Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-141133
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Alkynes
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Propargyl-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141135
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Alkynes
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Propargyl-PEG4-tetra-Ac-beta-D-galactose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141127
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Azide
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Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141054
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Alkynes
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N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140602
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PROTAC Synthesis
Azide
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Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130974
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ADC Synthesis
Tetrazine
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Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-134693
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Azide
PROTAC Synthesis
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Azido-C1-PEG4-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-C1-PEG4-C3-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-W110146
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- HY-141050
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PROTAC Synthesis
Alkynes
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N-PEG3-N'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-PEG3-N'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140556
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PROTAC Synthesis
Azide
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N-Boc-N-bis(PEG4-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Boc-N-bis(PEG4-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130543
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Azide
PROTAC Synthesis
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111-Trifluoroethyl-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 1,1,1-Trifluoroethyl-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140523
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PROTAC Synthesis
Azide
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Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140928
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Alkynes
PROTAC Synthesis
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Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140874
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PROTAC Synthesis
Azide
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Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140846
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Azide
PROTAC Synthesis
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N-Fmoc-N'-(azido-PEG4)-L-Lysine is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140809
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PROTAC Synthesis
Azide
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Azido-PEG4-(CH2)3OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-(CH2)3OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140854
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Azide
PROTAC Synthesis
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Azido-PEG4-(CH2)3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-(CH2)3-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140914
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Azide
PROTAC Synthesis
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Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Amide-C6-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140604
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PROTAC Synthesis
Azide
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Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140095
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Alkynes
PROTAC Synthesis
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N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-136084
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TCO
ADC Synthesis
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Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-151833
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Tetrazine
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Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-140518
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG4-acid) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140525
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PROTAC Synthesis
Azide
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N-(Azido-PEG2)-N-Boc-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140592
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PROTAC Synthesis
Azide
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Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-S-PEG4-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140546
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141091
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ADC Synthesis
Azide
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Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-136155
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ADC Synthesis
Azide
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Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140133
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ADC Synthesis
Azide
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PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-128834
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PROTAC Linker 20
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PROTAC Synthesis
Azide
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N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . N3-PEG4-C2-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-126515
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Alkynes
ADC Synthesis
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Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-154802
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TCO
|
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TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-141063
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Azide
|
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N-(m-PEG4)-N'-(azide-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140847
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Azide
PROTAC Synthesis
|
|
N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl/ether and PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130598
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PROTAC Synthesis
Azide
|
|
N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs N-(Azido-PEG3)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141064
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Azide
|
|
N-(azide-PEG3)-N'-(m-PEG4)-Benzothiazole Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-140565
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PROTAC Synthesis
Azide
|
|
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140563
-
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PROTAC Synthesis
Azide
|
|
N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140581
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140867
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Azide
PROTAC Synthesis
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N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140869
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Azide
PROTAC Synthesis
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N-(Azido-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140560
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PROTAC Synthesis
Azide
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N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141041
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Azide
PROTAC Synthesis
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N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-157407
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Alkynes
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Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan is a drug-linker conjugate for ADC (ADC Cytotoxin: Exatecan) .
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- HY-136090
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ADC Synthesis
Azide
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Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140828
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13-Azido-2,5,8,11-tetraoxatridecane
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Azide
PROTAC Synthesis
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m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . m-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140566
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PROTAC Synthesis
Azide
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N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Azido-PEG4-N-Boc-N-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-140921
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Azide
PROTAC Synthesis
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Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130969
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ADC Synthesis
Azide
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Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141066
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Azide
PROTAC Synthesis
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N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141048
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Azide
PROTAC Synthesis
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N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-D2117
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Labeling and Fluorescence Imaging
Tetrazine
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TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130946
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Azide
ADC Synthesis
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NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-141065
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Azide
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N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-103601
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VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4
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Azide
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(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-125541
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ADC Synthesis
DBCO
PROTAC Synthesis
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DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140821
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Azide
PROTAC Synthesis
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Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-128832
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MDM2 Ligand-Linker Conjugates 1; E3 ligase Ligand-Linker Conjugates 48
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Azide
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Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology. Nutlin-C1-amido-PEG4-C2-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-139859
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ADC Synthesis
Tetrazine
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APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D2234
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TCO
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SiR-PEG3-TCO is a near-infrared rhodamine fluorescent dye containing silica. SiR-PEG4-alkyne can be used in click chemistry .
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- HY-140820
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Azide
PROTAC Synthesis
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Bromo-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151649
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Alkynes
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Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an alkyne group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical .
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- HY-151670
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Azide
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Biotin-PEG(4)-SS-Azide is a click chemistry reagent containing an azide group. Biotin-PEG(4)-SS-Azide can be used for the research of various biochemical .
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- HY-151726
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Azide
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Azido-PEG(4)-Val-Cit-PAB-PNP is a click chemistry reagent containing an azide group.
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