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Results for "

PKM2-IN-1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Fluorescent Dye

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103617
    PKM2-IN-1
    10+ Cited Publications

    		 Pyruvate Kinase Cancer
    PKM2-IN-1 (compound 3k) is a pyruvate kinase M2 (PKM2) inhibitor with an IC50 of 2.95 μM .
    <em>PKM2-IN-1</em>
  • HY-D1877
    ZY-1

    		Pyruvate Kinase Others
    ZY-1 is a control molecule of ZY-2 (HY-D1876, a PKM2 fluorescent probe). ZY-1 shows a low fluorescence emission in HeLa, a cervical cancer cell abundant in PKM2 expression .
    ZY-1
  • HY-149275
    PKM2/PDK1-IN-1

    		Pyruvate Kinase PDK-1 Akt EGFR Apoptosis Cancer
    PKM2/PDK1-IN-1, one of shikonin thioether derivatives, is a dual inhibitor of PKM2/PDK1. PKM2/PDK1-IN-1 inhibits the proliferation of NSCLC cells, and induces apoptosis. PKM2/PDK1-IN-1 induces intercellular ROS production, and regulates the apoptotic proteins, to involves in mitochondrial and death receptor pathway .
    <em>PKM2/PDK1</em>-IN-1
  • HY-B1814
    Vitamin K5

    SynkamIN; SynkamIN base

    		 Pyruvate Kinase Bacterial Fungal Infection Cancer
    Vitamin K5 (Synkamin) is a photosensitizer and a antimicrobial agent. Vitamin K5 is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 induces apoptosis of colon 26 cells. Vitamin K5 can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages .
    Vitamin K5

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