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SNX10-PIKfyve

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-160477
    DC-SX029

    		PIKfyve NF-κB IKK Inflammation/Immunology
    DC-SX029 is a potent SNX10 protein-protein interaction (PPI) inhibitor with an estimated KD constant of ~0.935 μM by surface plasmon resonance (SPR). DC-SX029 blocks the SNX10-PIKfyve interaction, thereby decreased the TBK1/c-Rel signaling activation. DC-SX029 does not affect the protein level of SNX10. DC-SX029 has the potential for inflammatory bowel disease (IBD) research .
    DC-SX029

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