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Results for "

Salicylanilide

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

4

Peptides

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1408
    Salicylanilide
    2 Publications Verification

    2-Hydroxybenzanilide

    		 HIV Integrase HIV Infection
    Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virus by targeting HIV-1 integrase or reverse transcriptase.
    <em>Salicylanilide</em>
  • HY-17596
    Closantel
    5 Publications Verification

    		 Parasite Infection
    Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .
    Closantel
  • HY-17596A
    Closantel sodium
    5 Publications Verification

    		 Parasite Infection
    Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .
    Closantel sodium
  • HY-17598S
    Rafoxanide-13C6

    		Isotope-Labeled Compounds Parasite Infection
    Rafoxanide 13C6 is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent[1].
    Rafoxanide-13C6
  • HY-150063
    Antibacterial agent 116

    		Penicillin-binding protein (PBP) Bacterial Infection
    Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain .
    Antibacterial agent 116
  • HY-17594
    Oxyclozanide
    1 Publications Verification

    		 Oxidative Phosphorylation Parasite Bacterial Fungal Infection
    Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity .
    Oxyclozanide
  • HY-17594R
    Oxyclozanide (Standard)

    		Oxidative Phosphorylation Parasite Bacterial Fungal Infection
    Oxyclozanide (Standard) is the analytical standard of Oxyclozanide. This product is intended for research and analytical applications. Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity .
    Oxyclozanide (Standard)
  • HY-17596S
    Closantel-13C6

    		Isotope-Labeled Compounds Parasite Infection
    Closantel- 13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
    Closantel-13C6
  • HY-B0497S1
    Niclosamide-13C6

    BAY2353-13C6

    		 Isotope-Labeled Compounds STAT Parasite Antibiotic Infection Cancer
    Niclosamide- 13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
    Niclosamide-13C6
  • HY-155836
    hPL-IN-1

    		Others Metabolic Disease
    hPL-IN-1 (compound 2t) is a reversible inhibitor of pancreatic lipase (PL) (IC50=1.86 μM) for anti-obesity research .
    hPL-IN-1
  • HY-155837
    hPL-IN-2

    		Others Metabolic Disease
    hPL-IN-2 (compound 2u) is a potent, reversible, and non-competitive inhibitor of pancreatic lipase (IC50: 1.63 μM) and can be used in anti-obesity research .
    hPL-IN-2
  • HY-147369
    NFATc1-IN-1
    1 Publications Verification

    		 Nuclear Factor of activated T Cells (NFAT) Others
    NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research .
    NFATc1-IN-1

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