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atx3

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

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Recombinant Proteins

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Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-110078
    Eeyarestatin I
    2 Publications Verification

    		 p97 Apoptosis Cancer
    Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. Eeyarestatin I interferes at a step prior to proteasomal degradation. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects [3] .
    Eeyarestatin I

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