Search Result
Results for "
contact
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0508
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Rosin
1 Publications Verification
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Others
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Inflammation/Immunology
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Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis .
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- HY-N7087
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α-Methylene butyrolactone
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Drug Metabolite
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Tulipalin A (α-Methylene butyrolactone) is a glycoside. Tulipalin A is a causative allergen that induces Allergic contact dermatitides . Tulipalin A (α-Methylene butyrolactone) at low dose affects the functionality of immune cells, such as Jurkat T cells .
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- HY-B1946
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Others
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Others
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Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects .
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- HY-145941
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2-Acryloxyethyltrimethylammonium chloride
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Biochemical Assay Reagents
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Inflammation/Immunology
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AETA (2-Acryloxyethyltrimethylammonium chloride) can be used for the synthesis of hydrophilic polymers and hydrogels. Hydrogels are used for membranes, catheters, contact lenses, and drug delivery systems .
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- HY-N10100
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Others
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Others
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Epiglobulol is a natural product that can be isolated from Atalantia buxifolia. Epiglobulol is a principal components of essential oil which has significant contact toxicity against three stored-product insects .
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- HY-P1722
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Neurokinin Receptor
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Inflammation/Immunology
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Spantide II, an undecapeptide substance P (SP) analog, is a potent neurokinin-1 receptor (NK-1R) antagonist. Spantide II binds with NK-1R and blocks proinflammatory activities associated with SP. Spantide II can be used in the research of inflammatory skin disorders, such as psoriasis and contact dermatitis .
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- HY-100009
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Flufenamic acid butyl ester; Butyl flufenamate
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Others
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Inflammation/Immunology
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Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory agent. Ufenamate can be used for the research of skin diseases, such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliaria and atopic dermatitis .
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- HY-13706A
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TM30089
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Prostaglandin Receptor
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Inflammation/Immunology
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CAY10471 (TM30089) is a potent, selective, and orally active prostaglandin D2 receptor CRTH2 antagonist. CAY10471 attenuates the progression of tubulointerstitial fibrosis and chronic contact hypersensitivity (CHS) in animal model .
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- HY-B2030
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- HY-W040206
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Others
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Others
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Diflufenican is a contact, selective herbicide used to specifically control some broad leaved weeds .
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- HY-B1877
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Others
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Cancer
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Nitrofen is a selective contact herbicide. Nitrofen is a retinal dehydrogenase and protoporphyrinogen oxidase inhibitor .
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- HY-B2030S
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- HY-W009688
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Others
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Inflammation/Immunology
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Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice .
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- HY-106714
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Drug Metabolite
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Inflammation/Immunology
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Clocortolone pivalate is a synthetic glucocorticoid corticosteroid and corticosteroid ester. Clocortolone pivalate is indicated for seborrheic dermatitis, contact dermatitis, atopic dermatitis and psoriasis .
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- HY-D1177
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Fluorescent Dye
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Solvent orange 60 is a cyclic ketone dye commonly used in plastic materials such as eyeglass frames and has been shown to cause contact allergies.
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- HY-W010056
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Others
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Inflammation/Immunology
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Diethyl fumarate is a decomposition product of Malathion (an insecticide). Diethyl fumarate is a reputed skin irritant. Diethyl fumarate can causes non-immunologic contact urticaria on skin .
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- HY-N3076
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(-)-Phyllostine; Phyllostin
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Others
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Others
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Phyllostine ((-)-Phyllostine) can be isolated from D. miriciae. Phyllostine exhibits strong antifeedant, contact toxicity, and oviposition deterrent activities against P. xylostella .
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- HY-130313
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Amino Acid Derivatives
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Inflammation/Immunology
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Sodium lauroyl glutamate is an anionic amino acid surfactant. Sodium lauroyl glutamate has the irritant contact dermatitis potential, and possible anti-irritating potential in a surfactant mixture on human skin .
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- HY-W040206S
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Isotope-Labeled Compounds
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Others
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Diflufenican-d3 is the deuterium labeled Diflufenican[1]. Diflufenican is a contact, selective herbicide used to specifically control some broad leaved weeds[2].
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- HY-B0544
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Sodium Picosulphate
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Others
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Metabolic Disease
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Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications .
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- HY-W089777
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GPTMS
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Biochemical Assay Reagents
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Others
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3-Glycidyloxypropyltrimethoxysilane (GPTMS) is the silicon source for the preparation of inorganic–organic hybrid polymers, which is used for hard coatings of organic polymers, contact lens materials in the optical industry, electronics, membranes, sensors, nanoimprinting, wave guides, and biology .
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- HY-A0150
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7a-Chloro-16a-methyl prednisolone
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Glucocorticoid Receptor
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Inflammation/Immunology
Cancer
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Alclometasone (7a-Chloro-16a-methyl prednisolone) is a glucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis, eczema, psoriasis and allergic dermatitis .
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- HY-136611
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Drug Metabolite
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Infection
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ω-Hydroxy-DEET is a major metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). ω-Hydroxy-DEET has anti-proliferative effects. DEET is a spatial repellent and an irritant that commonly used to prevent contact with mosquitoes .
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- HY-D0154
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Tetramethylrhodamine-6-isothiocyanate
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Fluorescent Dye
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Others
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6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .
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- HY-W013780S1
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Isotope-Labeled Compounds
Fungal
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Infection
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Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
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- HY-B1946S
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Isotope-Labeled Compounds
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Others
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Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
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- HY-B2033
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Fungal
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Infection
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Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .
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- HY-116835
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CCR
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Inflammation/Immunology
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BI 6901 is a potent, selective CCR10 antagonist (pIC50=9.0). BI 6901 shows high selectivity over other GPCRs, including a number of other chemokine receptors. BI 6901 is efficacious in the murine DNFB model of contact hypersensitivity and can be used for inflammation research .
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- HY-13516
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Apoptosis
Autophagy
Filovirus
HIV
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Infection
Inflammation/Immunology
Cancer
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Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties .
Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .
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- HY-112531
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Others
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Others
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Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .
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- HY-112531A
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Others
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Others
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Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .
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- HY-114348
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DiNAC; (Ac-Cys-OH)2
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Others
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Cardiovascular Disease
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N,N'-diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine is a potent, orally active modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits .
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- HY-N9698
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Others
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Others
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1,5-Diphenyl-2-penten-1-one is a natural product extracted from Stellera chamaejasme. 1,5-Diphenyl-2-penten-1-one has strong contact activity and very good anti-feedant activity against Aphis gossypii and Schizaphis graminum .
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- HY-138301
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DS37262926
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β-catenin
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Cancer
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Miclxin (DS37262926) is a potent inhibitor of mutant β-catenin, involving in Wnt signaling pathway. Miclxin induces β-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex .
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- HY-P10306
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Bacterial
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Infection
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Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .
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- HY-B2033S
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Fungal
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Infection
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Pyrimethanil- 13C, 15N2 is the 13C-labeled and 15N-labeled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3].
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- HY-110196
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Others
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Others
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(S)-PFI-2 hydrochloride is an inhibitor of lysine methyltransferase SETD7 and is approximately 500-fold more active than its enantiomer (R)-PFI-2. (R)-PFI-2 is a cofactor-dependent and substrate-competitive inhibitor. (R)-PFI-2 can occupy the substrate peptide binding groove of SETD7 (including the catalytic lysine binding channel) and interact with the cofactor The donor methyl group is in direct contact. However, (S)-PFI-2 was not observed to have the same interaction as (R)-PFI-2 .
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- HY-134098
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Adipic acid diisopropyl ester
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TRP Channel
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Others
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Diisopropyl adipate is an alternative plasticizer and a TRPA1 activator. Diisopropyl adipate activates TRPA1 and enhances FITC-induced contact hypersensitivity (CHS).Diisopropyl adipate also serves as an ingredient in cosmetics and drug formulations topically applied to the skin. Diisopropyl adipate can be used as an excipient, such as emollients, plasticizers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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Cat. No. |
Product Name |
Type |
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- HY-D1177
-
|
Dyes
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Solvent orange 60 is a cyclic ketone dye commonly used in plastic materials such as eyeglass frames and has been shown to cause contact allergies.
|
-
- HY-D0154
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Tetramethylrhodamine-6-isothiocyanate
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Fluorescent Dyes/Probes
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6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .
|
Cat. No. |
Product Name |
Type |
-
- HY-W089777
-
GPTMS
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Biochemical Assay Reagents
|
3-Glycidyloxypropyltrimethoxysilane (GPTMS) is the silicon source for the preparation of inorganic–organic hybrid polymers, which is used for hard coatings of organic polymers, contact lens materials in the optical industry, electronics, membranes, sensors, nanoimprinting, wave guides, and biology .
|
-
- HY-145941
-
2-Acryloxyethyltrimethylammonium chloride
|
Biochemical Assay Reagents
|
AETA (2-Acryloxyethyltrimethylammonium chloride) can be used for the synthesis of hydrophilic polymers and hydrogels. Hydrogels are used for membranes, catheters, contact lenses, and drug delivery systems .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1722
-
|
Neurokinin Receptor
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Inflammation/Immunology
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Spantide II, an undecapeptide substance P (SP) analog, is a potent neurokinin-1 receptor (NK-1R) antagonist. Spantide II binds with NK-1R and blocks proinflammatory activities associated with SP. Spantide II can be used in the research of inflammatory skin disorders, such as psoriasis and contact dermatitis .
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- HY-P10306
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Bacterial
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Infection
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Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-B1946S
-
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Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
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- HY-B2030S
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Propanil-d5 is the deuterium labeled Propanil. Propanil is a widely used contact herbicide, mainly use in rice production.
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- HY-W040206S
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Diflufenican-d3 is the deuterium labeled Diflufenican[1]. Diflufenican is a contact, selective herbicide used to specifically control some broad leaved weeds[2].
|
-
-
- HY-W013780S1
-
|
Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
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- HY-B2033S
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Pyrimethanil- 13C, 15N2 is the 13C-labeled and 15N-labeled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3].
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