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Results for "

serpin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) PAI-1 (1) Ser/Thr Protease (1)
By Research Areas:	Cancer (1) Infection (1) Neurological Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-33299

Serpin B9-IN-1 BTCA	Others	Cancer
Serpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 (SB9); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM) .

HY-E70194

Endoproteinase Glu-C V8 protease; Glu-C	Ser/Thr Protease	Others
Endoproteinase GluC (V8 protease) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .

HY-150514

ARN1468	Others	Infection
ARN1468 (compound 5) is an orally active and potent *serpins* inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC₅₀ values of 8.64, 19.3, 11.2, and 6.27 μM .

HY-14759

Aleplasinin PAZ-417	PAI-1 Amyloid-β	Neurological Disease
Aleplasinin is an orally active, potent, BBB-penetrated and selectiveSERPINE1 (PAI-1, Plasminogen activator inhibitor-1) inhibitor. Aleplasinin increases amyloid-β (Aβ) catabolism and ameliorates amyloid-related pathology. Aleplasinin improves memory deficiency. Aleplasinin can be used for Alzheimer's disease research .

Recombinant Proteins Recommended:

Serpin (Protease Inhibitor)

Species:	Human (35) Mouse (29) Rat (8) Cynomolgus (2) Pig (1)
Tag:	His (66) Tag Free (5) Avi (1) Myc (1) GST (1) Trx (1) Fc (3)
Source:	HEK293 (58) CHO (1) Sf9 insect cells (8) P. pastoris (1) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P7385A

	Serpin B5/Maspin Protein, Human (His) rHuMaspin; serpin B5; PI-5	Human	E. coli
	Serpin B5/Maspin Protein is a tumor suppressor and a unique member of the serpin family. Maspin inhibits cancer cell invasion, attachment to the extracellular matrix, increases sensitivity to apoptosis, and inhibits angiogenesis. Maspin interacting with diverse group of intercellular and extracellular proteins, regulating cell adhesion, motility, apoptosis, and critically involved in mammary gland development. Maspin acts as an endogenous inhibitor of histone deacetylase (HDAC1). Serpin B5/Maspin Protein, Human (His) is the recombinant human-derived Serpin B5/Maspin protein, expressed by E. coli, with His labeled tag. The total length of Serpin B5/Maspin Protein, Human (His) is 375 a.a., with molecular weight of approximately 40-45 kDa.

HY-P76060

	Serpin A11 Protein, Mouse (HEK293, His) serpin A11; serpina11; Gm895	Mouse	HEK293
	Serpin A11 protein is a member of the serpin family and is an important serine protease inhibitor that regulates proteolytic activity. Its study deepens our understanding of cellular processes related to proteolysis and has potential applications in therapy. Serpin A11 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A11 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A11 Protein, Mouse (HEK293, His) is 403 a.a., with molecular weight of 50-70 kDa.

HY-P7385

	Serpin B5/Maspin Protein, Human (375 a.a) rHuMaspin; serpin B5; PI-5	Human	E. coli
	Serpin B5/Maspin Protein, Human (375 a.a) could inhibit invasion and motility of mammary tumors. Maspin Protein, Human is also found to be a potent angiogenesis inhibitor.

HY-P73651

	Serpin A8/Angiotensinogen Protein, Rat (HEK293, His) Angiotensinogen; serpin A8; AGT; serpinA8	Rat	HEK293
	Serpin A8 (or angiotensinogen) is a key regulator of the renin-angiotensin system, affecting blood pressure, fluid and electrolyte balance. As a vasoconstrictor, it directly affects vascular smooth muscle and affects myocardial contractility and heart rate through the sympathetic nervous system. Serpin A8/Angiotensinogen Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A8/Angiotensinogen Protein, Rat (HEK293, His) is 453 a.a., with molecular weight of 58-75 kDa.

HY-P73652

	Serpin A8/Angiotensinogen Protein, Mouse (HEK293, His) Angiotensinogen; serpin A8; AGT; serpinA8	Mouse	HEK293
	Serpin A8 (or angiotensinogen) is an important regulator in the renin-angiotensin system, fine-tuning blood pressure and electrolyte balance. This multifunctional protein acts as a potent vasoconstrictor, affecting vascular smooth muscle and affecting cardiac function via the sympathetic nervous system. Serpin A8/Angiotensinogen Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A8/Angiotensinogen Protein, Mouse (HEK293, His) is 453 a.a., with molecular weight of ~58 kDa.

HY-P73653

	Serpin A8/Angiotensinogen Protein, Human (HEK293, His) Angiotensinogen; serpin A8; AGT; serpinA8	Human	HEK293
	Serpin A8/angiotensinogen protein is an important component of the renin-angiotensin system (RAS), which regulates blood pressure, fluid balance, and electrolyte homeostasis. Serpin A8/Angiotensinogen Protein, Human (HEK293, His) is the recombinant human-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A8/Angiotensinogen Protein, Human (HEK293, His) is 452 a.a., with molecular weight of 52-64 kDa.

HY-P72477

	Serpin A8/Angiotensinogen Protein, Human (HEK293, His, solution) Angiotensinogen; serpin A8; AGT and serpinA8	Human	HEK293
	Serpin A8/angiotensinogen protein is an important component of the renin-angiotensin system (RAS), which regulates blood pressure, fluid balance, and electrolyte homeostasis. Serpin A8/Angiotensinogen Protein, Human (HEK293, His, solution) is the recombinant human-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A8/Angiotensinogen Protein, Human (HEK293, His, solution) is 452 a.a., with molecular weight of 55.0-72.27 kDa.

HY-P74556

	Serpin A1 Protein, Rat (HEK293, His) Alpha-1-antiproteinase; serpin A1; A1A	Rat	HEK293
	The serpin A1 protein is a vigilant guardian in cell regulation, effectively inhibiting elastase and providing a strong barrier to its enzymatic activity. Serpin A1 has moderate affinity for plasmin and thrombin and exhibits versatility in binding a range of serine proteases. Serpin A1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin A1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A1 Protein, Rat (HEK293, His) is 387 a.a., with molecular weight of ~45.2 kDa.

HY-P71304

	Serpin B12 Protein, Human (HEK293, His) serpinB12; serpin B12; Serine Protease Inhibitor-clade B12	Human	HEK293
	Serpin B12 Protein inhibits trypsin and plasmin, excluding thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. It may have a role in cell differentiation, interacting with SLFN12 in a pathway regulating differentiation, and potentially interacting with USP14. Serpin B12 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B12 Protein, Human (HEK293, His) is 425 a.a., with molecular weight of ~55.0 kDa.

HY-P73372

	Serpin F1 Protein, Mouse (HEK293, His) Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; serpin F1	Mouse	HEK293
	Serpin F1 is a neurotrophin that significantly induces extensive neuronal differentiation of retinoblastoma cells and exhibits potent anti-angiogenic effects. Its unique conformation lacks the S (stress) to R (relaxation) transition typical of active serpins, resulting in a lack of serpin activity. Serpin F1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin F1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin F1 Protein, Mouse (HEK293, His) is 398 a.a., with molecular weight of 60-65 kDa.

HY-P73412

	Serpin A3 Protein, Human (HEK293, His) Alpha-1-Antichymotrypsin; ACT; serpin A3; serpinA3; AACT	Human	HEK293
	Serpin A3 protein is a serine protease inhibitor on chromosome 14 that affects protease targeting through tissue-specific polymorphisms. Sequence variants are associated with Alzheimer's disease, while deficiencies are associated with liver disease. Serpin A3 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A3 Protein, Human (HEK293, His) is 398 a.a., with molecular weight of ~50-70 kDa.

HY-P74557

	Serpin F1 Protein, Rat (HEK293, His) Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; serpin F1	Rat	HEK293
	Serpin F1 Protein, part of the secreted frizzled-related protein (sFRP) family, modulates Wnt signaling pathways. As a member, Serpin F1 likely interacts with Wnt ligands and frizzled receptors, regulating crucial cellular processes. The unique structural characteristics of Serpin F1 within the sFRP family, marked by the absence of conserved residue(s) for feature annotation propagation, underscore its distinctive role in Wnt signaling modulation. Despite lacking certain conserved elements, Serpin F1's specific attributes may contribute to its distinct influence on cellular activities, such as proliferation, differentiation, or tissue development. Serpin F1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin F1 protein, expressed by HEK293, with C-His labeled tag. The total length of Serpin F1 Protein, Rat (HEK293, His) is 399 a.a., with molecular weight of ~45.9 kDa.

HY-P77197

	Serpin B12 Protein, Mouse (sf9, His) serpinB12; serpin B12; Serine Protease Inhibitor-clade B12	Mouse	Sf9 insect cells
	Serpin B12 inhibits trypsin and plasmin but not thrombin, coagulation factor Xa, and urokinase-type plasminogen activator. Additionally, it interacts with SLFN12, contributing to cellular differentiation pathways, showcasing its multifunctional nature beyond classical protease inhibition. Serpin B12 Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin B12 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Serpin B12 Protein, Mouse (sf9, His) is 423 a.a., with molecular weight of ~58 kDa.

HY-P75581

	*Antithrombin III/Serpin* C1 Protein, Cynomolgus (HEK293, His)** Antithrombin-III; ATIII; serpin C1; serpinC1; AT3	Cynomolgus	HEK293
	Antithrombin III, also known as Serpin C1, forms a protease inhibitory heterodimer with TMPRSS7. This interaction exemplifies the regulatory role of antithrombin III as a serine protease inhibitor, highlighting its ability to modulate TMPRSS7 activity. Antithrombin III/Serpin C1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Antithrombin III/Serpin C1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Antithrombin III/Serpin C1 Protein, Cynomolgus (HEK293, His) is 430 a.a., with molecular weight of ~55-75 kDa.

HY-P71079

	Serpin A7 Protein, Human (HEK293, His) Thyroxine-Binding Globulin; serpin A7; T4-Binding Globulin; serpinA7; TBG	Human	HEK293
	Serpin A7, or thyroxine-binding globulin (TBG), acts as a glycoprotein carrier for thyroid hormones, specifically binding and transporting thyroxine (T4) and triiodothyronine (T3). TBG regulates the availability and distribution of thyroid hormones critical for physiological processes like metabolism and growth. Mutations in the SERPINA7 gene can affect TBG function, influencing thyroid hormone levels. Serpin A7 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A7 Protein, Human (HEK293, His) is 395 a.a., with molecular weight of 55-65 kDa.

HY-P73656

	Serpin A7 Protein, Mouse (HEK293, His) Thyroxine-Binding Globulin; serpin A7; T4-Binding Globulin; serpinA7; TBG	Mouse	HEK293
	Serpin A7 protein binds hormones and inhibits serine-type endopeptidase activity. It is involved in negative regulation of endopeptidase activity, response to vitamin A, and thyroid hormone transport. It is located in the extracellular region and is active in the extracellular space. Serpin A7 is orthologous to human SERPINA7 and is expressed primarily in liver E18, liver E14.5, and two other tissues. Serpin A7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A7 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A7 Protein, Mouse (HEK293, His) is 398 a.a., with molecular weight of 55-60 kDa.

HY-P72831A

	*Antithrombin III/Serpin* C1 Protein, Human (HEK293, C-His)** Antithrombin-III; ATIII; serpin C1; serpinC1; AT3	Human	HEK293
	Antithrombin III/Serpin C1 protein, the main plasma serine protease inhibitor, regulates the blood coagulation cascade. It inhibits thrombin, matriptase-3/TMPRSS7, and factors IXa, Xa, and XIa, with enhanced potency in the presence of heparin. Furthermore, it forms a protease-inhibiting heterodimer with TMPRSS7. Antithrombin III/Serpin C1 Protein, Human (HEK293, C-His) is the recombinant human-derived Antithrombin III/Serpin C1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of Antithrombin III/Serpin C1 Protein, Human (HEK293, C-His) is 430 a.a., with molecular weight of 55-60 kDa.

HY-P77198

	Serpin B4 Protein, Human (sf9, His) serpin B4; Leupin; Peptidase inhibitor 11; PI-11; SCCA-2	Human	Sf9 insect cells
	Serpin B4 is a protease inhibitor that may modulate the host immune response against tumor cells, suggesting a crucial role in fine-tuning immune balance. Its ability to inhibit proteases emphasizes its importance in influencing key regulatory pathways, enhancing the immune system's effectiveness against cancer cells. Serpin B4 Protein, Human (sf9, His) is the recombinant human-derived Serpin B4 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Serpin B4 Protein, Human (sf9, His) is 390 a.a., with molecular weight of ~45 kDa.

HY-P7419

	Vaspin Protein, Human 2 Publications Verification rHuVaspin; serpin A12; OL-64	Human	E. coli
	Vaspin Protein, Human, as a secretory adipokine, exerts a protective role on insulin resistance.

HY-P71299

	Vaspin Protein, Human (GST) serpin A12; OL-64; Visceral Adipose Tissue-Derived Serine Protease Inhibitor; Vaspin; Visceral Adipose-Specific serpin; serpinA12	Human	E. coli
	Vaspin is an adipokine that regulates adipogenesis, metabolism, and inflammation by binding to the chemokine receptors CMKLR1 and CMKLR2. It mainly regulates adipocyte differentiation and affects lipid and glucose metabolism genes. Vaspin Protein, Human (GST) is the recombinant human-derived Vaspin protein, expressed by E. coli , with N-GST labeled tag. The total length of Vaspin Protein, Human (GST) is 394 a.a., with molecular weight of ~72.0 kDa.

HY-P73336

	Serpin E1 Protein, Rat (HEK293, Fc) Plasminogen activator inhibitor 1; PAI-1; serpin E1; serpine1; Planh1	Rat	HEK293
	Serpin E1 is a serine protease inhibitor that regulates TMPRSS7 and inhibits tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). It can significantly downregulate fibrinolysis and control thrombus degradation. Serpin E1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Serpin E1 Protein, Rat (HEK293, Fc) is 402 a.a., with molecular weight of ~70 kDa.

HY-P72831

	*Antithrombin III/Serpin* C1 Protein, Human (432a.a, HEK293, His)** Antithrombin-III; ATIII; serpin C1; serpinC1; AT3	Human	HEK293
	Antithrombin III/Serpin C1 protein, the main plasma serine protease inhibitor, regulates the blood coagulation cascade. It inhibits thrombin, matriptase-3/TMPRSS7, and factors IXa, Xa, and XIa, with enhanced potency in the presence of heparin. Furthermore, it forms a protease-inhibiting heterodimer with TMPRSS7. Antithrombin III/Serpin C1 Protein, Human (432a.a, HEK293, His) is the recombinant human-derived Antithrombin III/Serpin C1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Antithrombin III/Serpin C1 Protein, Human (432a.a, HEK293, His) is 432 a.a., with molecular weight of 55-60 kDa.

HY-P73655

	Serpin E1 Protein, Rat (HEK293, His) Plasminogen activator inhibitor 1; PAI-1; serpin E1; serpine1; Planh1	Rat	HEK293
	Serpin E1 Protein, Rat (HEK293, His) is one important member of the serine proteinase inhibitor E superfamily that plays a crucial role in the fibrinolytic system. The Serpin E1 protein is a single-chain glycoprotein composed of 379 amino acids. The active site of the protein is Arg346-Met347. SERPINE1 encodes plasminogen activator inhibitor type 1 (PAI-1), which serves as the primary inhibitor of urokinase plasminogen activator (uPA) and tissue-type plasminogen activator (tPA). The Serpin E1 protein can quickly inhibit the formation of plasmin. Serpin E1 can be transcribed through several signaling cascades, including pro-fibrogenic and pro-inflammatory pathways. Serpin E1 is a serine proteinase inhibitor, serves as an important regulator of extracellular matrix remodeling. Serpin E1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-His, C-10*His labeled tag. The total length of Serpin E1 Protein, Rat (HEK293, His) is 379 a.a., with molecular weight of 48-60 kDa.

HY-P70584

	Serpin F1 Protein, Mouse (375a.a) Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; serpin F1; Stromal cell-derived factor 3.	Mouse	E. coli
	Serpin F1 is a neurotrophin that significantly induces extensive neuronal differentiation of retinoblastoma cells and exhibits potent anti-angiogenic effects. Its unique conformation lacks the S (stress) to R (relaxation) transition typical of active serpins, resulting in a lack of serpin activity. Serpin F1 Protein, Mouse (375a.a) is the recombinant mouse-derived Serpin F1 protein, expressed by E. coli , with tag free. The total length of Serpin F1 Protein, Mouse (375a.a) is 375 a.a., with molecular weight of ~40.0 kDa.

HY-P71292

	Serpin A10 Protein, Human (HEK293, His) Protein Z-Dependent Protease Inhibitor; PZ-Fependent Protease Inhibitor; PZI; serpin A10; serpinA10; ZPI	Human	HEK293
	Serpin A10 protein inhibits coagulation proteases, such as factor Xa, in the presence of PROZ, calcium, and phospholipids. It can also inhibit factor XIa without cofactors. Serpin A10 interacts with PROZ to exert its inhibitory effects on these coagulation factors. Serpin A10 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A10 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A10 Protein, Human (HEK293, His) is 423 a.a., with molecular weight of 55-80 kDa.

HY-P71302

	Serpin A3N Protein, Mouse (HEK293, His) Serine protease inhibitor A3N; serpin A3N; serpina3n; Spi2	Mouse	HEK293
	The serpin A3N protein is ubiquitously found in a variety of tissues, showing elevated expression in the brain, heart, liver, lung, spleen, testis, and thymus, implying a variety of physiological functions. In contrast, it shows lower expression in bone marrow, kidney, and skeletal muscle, suggesting a tissue-specific pattern of regulation. Serpin A3N Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A3N protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A3N Protein, Mouse (HEK293, His) is 398 a.a., with molecular weight of 57-61 kDa.

HY-P71841

	Serpin A3N Protein, Mouse (P.pastoris, His) serpina3n; Spi2; Serine protease inhibitor A3N; serpin A3N	Mouse	P. pastoris
	The serpin A3N protein is ubiquitously found in a variety of tissues, showing elevated expression in the brain, heart, liver, lung, spleen, testis, and thymus, implying a variety of physiological functions. In contrast, it shows lower expression in bone marrow, kidney, and skeletal muscle, suggesting a tissue-specific pattern of regulation. Serpin A3N Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Serpin A3N protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Serpin A3N Protein, Mouse (P.pastoris, His) is 398 a.a., with molecular weight of ~46.8 kDa.

HY-P73654

	Serpin G1 Protein, Rat (HEK293, His) C1IN; C1INH; serpinG1; serpin G1; Plasma protease C1 inhibitor	Rat	HEK293
	Serpin G1 protein binds complement and inhibits serine-type endopeptidases. It is located in the extracellular space and is involved in aging. Serpin G1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin G1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin G1 Protein, Rat (HEK293, His) is 482 a.a., with molecular weight of ~ 70-95 kDa.

HY-P74558

	Serpin A3N Protein, Rat (HEK293, His) serpina3n; Spi2; Serine protease inhibitor A3N; serpin A3N	Rat	HEK293
	The Serpin A3N Protein, belonging to the serpin family, is predominantly expressed in the liver, where it regulates protease activity. As a serine protease inhibitor, Serpin A3N plays a crucial role in modulating enzymatic processes within the liver, highlighting its significance in hepatic functions and maintaining the balance of proteolytic activities in this vital organ. Serpin A3N Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin A3N protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A3N Protein, Rat (HEK293, His) is 389 a.a., with molecular weight of 50-65 kDa.

HY-P76639

	Serpin A10 Protein, Mouse (HEK293, His) Protein Z-Dependent Protease Inhibitor; PZ-Fependent Protease Inhibitor; PZI; serpin A10; serpinA10; ZPI	Mouse	HEK293
	Serpin A10 Protein, an inhibitor, regulates by inhibiting the activity of coagulation protease factor Xa in the presence of PROZ, calcium, and phospholipids. It also shows inhibitory effects on factor XIa even without cofactors, highlighting its versatility in modulating key components of the coagulation cascade. Serpin A10 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A10 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A10 Protein, Mouse (HEK293, His) is 427 a.a., with molecular weight of 60-80 kDa.

HY-P7491

	Serpin A1a Protein, Mouse (HEK293, His) rMuAlpha-1-antitrypsin 1-1, His; serpin A1a; Alpha-1-antitrypsin 1-1	Mouse	HEK293
	Alpha-1 protease inhibitor 1 Protein, Mouse (HEK293, His) is a mouse recombinant Serpin A1a with a His tag at the C-terminus. Alpha-1 protease inhibitor 1 Protein, Mouse (HEK293, His) is produced by Mammalian expression system and the target gene encoding Glu25-Lys413 is expressed.

HY-P71293

	Serpin D1 Protein, Mouse (HEK293, His) Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; serpin D1	Mouse	HEK293
	Serpin D1 is a thrombin inhibitor that is activated by glycosaminoglycans such as heparin or dermatan sulfate. In the presence of dermatan sulfate, HC-II surpasses antithrombin III (AT) as the primary thrombin inhibitor. Serpin D1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin D1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin D1 Protein, Mouse (HEK293, His) is 455 a.a., with molecular weight of 70-90 kDa.

HY-P71300

	Vaspin Protein, Human (HEK293, His) serpin A12; OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin; serpinA12	Human	HEK293
	Vaspin is an adipokine that regulates adipogenesis, metabolism, and inflammation by binding to the chemokine receptors CMKLR1 and CMKLR2. It mainly regulates adipocyte differentiation and affects lipid and glucose metabolism genes. Vaspin Protein, Human (HEK293, His) is the recombinant human-derived Vaspin protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Vaspin Protein, Human (HEK293, His) is 394 a.a., with molecular weight of 50-60 kDa.

HY-P71306

	Serpin B9 Protein, Human (HEK293, His) Cytoplasmic antiproteinase 3; Peptidase inhibitor 9; CAP3; PI-9; serpin B9	Human	HEK293
	The Serpin B9 Protein, a member of the serpin family, crucially regulates immune responses by specifically inhibiting granzyme B, a protease involved in immune cell-mediated apoptosis. Acting as a potent inhibitor, Serpin B9 modulates granzyme B's cytotoxic activity, fine-tuning immune responses and preventing unwarranted cell death, emphasizing its significance in maintaining immune balance. Serpin B9 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B9 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B9 Protein, Human (HEK293, His) is 376 a.a., with molecular weight of 35-40 kDa.

HY-P73526

	Serpin G1 Protein, Human (500a.a, HEK293, His) C1IN; C1INH; serpinG1; serpin G1; Plasma protease C1 inhibitor	Human	HEK293
	Serpin G1, also known as C1-inhibitor, controls C1 complex activation by forming a proteolytically inactive complex with C1r or C1s proteases. Its interactions regulate physiological pathways like complement activation, blood coagulation, fibrinolysis, and kinin generation. As a potent inhibitor of FXIIa, chymotrypsin, and kallikrein, Serpin G1 binds to E. coli stcE, protecting against complement-mediated lysis, and engages with MASP1, showcasing its intricate involvement in various cellular processes. Serpin G1 Protein, Human (500a.a, HEK293, His) is the recombinant human-derived Serpin G1 protein, expressed by HEK293, with C-10*His labeled tag. The total length of Serpin G1 Protein, Human (500a.a, HEK293, His) is 478 a.a., with molecular weight of ~110 kDa.

HY-P71143

	Serpin A4 Protein, Human (HEK293, His) Kallistatin; Kallikrein Inhibitor; Peptidase Inhibitor 4; PI-4; serpin A4; serpinA4; KST; PI4	Human	HEK293
	Serpin A4 Protein inhibits tissue kallikrein's amidolytic and kininogenase activities by forming a heat- and SDS-stable equimolar complex with the enzyme. Tissue kallikrein concurrently cleaves the reactive site of Serpin A4, producing a small C-terminal fragment. The protein, existing as a monomer and occasionally forming homodimers, demonstrates its regulatory role in modulating tissue kallikrein-mediated enzymatic activities. Serpin A4 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin A4 Protein, Human (HEK293, His) is 407 a.a., with molecular weight of 60-80 kDa.

HY-P70498

	Serpin F1 Protein, Human (HEK293, His) Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 Protein; EPC-1; serpin F1; serpinF1; PEDF	Human	HEK293
	Serpin F1 protein, a neurotrophic factor, crucially promotes extensive neuronal differentiation in retinoblastoma cells and serves as a potent inhibitor of angiogenesis. Unlike active serpins, Serpin F1 does not undergo the typical S (stressed) to R (relaxed) conformational transition, lacking serine protease inhibitory activity. It also interacts with PNPLA2, enhancing the phospholipase A2 activity of PNPLA2. Serpin F1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin F1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin F1 Protein, Human (HEK293, His) is 399 a.a., with molecular weight of ~50.0 kDa.

HY-P71054

	Serpin A3 Protein, Human (K267R, HEK293, His) Alpha-1-Antichymotrypsin; ACT; Cell Growth-Inhibiting Gene 24/25 Protein; serpin A3; serpinA3; AACT	Human	HEK293
	Serpin A3 Proteinas, with unclear physiological function, inhibits neutrophil cathepsin G and mast cell chymase, involved in angiotensin-1 to angiotensin-2 conversion. Serpin A3 also interacts with DNAJC1. Serpin A3 Protein, Human (K267R, HEK293, His) is the recombinant human-derived Serpin A3 protein, expressed by HEK293 , with C-6*His labeled tag and K267R mutation. The total length of Serpin A3 Protein, Human (K267R, HEK293, His) is 400 a.a., with molecular weight of 56-80 kDa.

HY-P70970

	Serpin B6 Protein, Human (Trx-His) serpin B6; Cytoplasmic Antiproteinase; CAP; Peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; serpinB6; PI6; PTI	Human	E. coli
	Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (Trx-His) is the recombinant human-derived Serpin B6 protein, expressed by E. coli , with N-Trx, N-6*His labeled tag. The total length of Serpin B6 Protein, Human (Trx-His) is 376 a.a., with molecular weight of 58-60 kDa.

HY-P71077

	Serpin E1 Protein, Human (HEK293, His) Plasminogen Activator Inhibitor 1; PAI; PAI-1; Endothelial Plasminogen Activator Inhibitor; serpin E1; serpinE1; PAI1; PLANH1	Human	HEK293
	Serpin E1 is a serine protease inhibitor that regulates various cellular processes by inhibiting TMPRSS7, tissue-type plasminogen activator (PLAT), and urokinase-type plasminogen activator (PLAU). During fibrinolysis, it downregulates PLAT to control thrombus degradation and acts as a PLAU inhibitor to regulate cell adhesion. Serpin E1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin E1 Protein, Human (HEK293, His) is 379 a.a., with molecular weight of ~44-51 kDa.

HY-P70498A

	Serpin F1 Protein, Human (HEK293, N-His) Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 Protein; EPC-1; serpin F1; serpinF1; PEDF	Human	HEK293
	Serpin F1 protein, a neurotrophic factor, crucially promotes extensive neuronal differentiation in retinoblastoma cells and serves as a potent inhibitor of angiogenesis. Unlike active serpins, Serpin F1 does not undergo the typical S (stressed) to R (relaxed) conformational transition, lacking serine protease inhibitory activity. It also interacts with PNPLA2, enhancing the phospholipase A2 activity of PNPLA2. Serpin F1 Protein, Human (HEK293, N-His) is the recombinant human-derived Serpin F1 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of Serpin F1 Protein, Human (HEK293, N-His) is 399 a.a., with molecular weight of ~49.37 kDa.

HY-P72055

	Serpin A5 Protein, Mouse (Baculovirus, His) serpina5; Pci; Plasma serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; serpin A5	Mouse	Sf9 insect cells
	Serpin A5 protein is a heparin-dependent serine protease inhibitor that controls proteolytic activity in body fluids. It binds irreversibly to the serine activation site, inactivating serine proteases and regulating intravascular and extravascular proteolysis. Serpin A5 Protein, Mouse (Baculovirus, His) is the recombinant mouse-derived Serpin A5 protein, expressed by Sf9 insect cells , with N-10*His labeled tag. The total length of Serpin A5 Protein, Mouse (Baculovirus, His) is 381 a.a., with molecular weight of ~45.3 kDa.

HY-P76640

	Serpin B6 Protein, Human (sf9, His) serpin B6; Cytoplasmic Antiproteinase; CAP; Peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; serpinB6; PI6; PTI	Human	Sf9 insect cells
	Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (sf9, His) is the recombinant human-derived Serpin B6 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Serpin B6 Protein, Human (sf9, His) is 375 a.a., with molecular weight of ~43 kDa.

HY-P700821

	*Alpha-2-Antiplasmin/Serpin* F2 Protein, Cynomolgus (HEK293, His)** Alpha-2-AP; AAP; PLI; serpinF2; A2AP; ALPHA-2-PI; API; serpin F2	Cynomolgus	HEK293
	Alpha-2-antiplasmin/serpin F2 protein is a member of the serine protease inhibitor family and can significantly inhibit plasmin to regulate thrombolysis. Synthesized in the liver and circulating in the blood, it prevents excessive fibrinolysis and ensures clot stabilization. Alpha-2-Antiplasmin/Serpin F2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Alpha-2-Antiplasmin/Serpin F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Alpha-2-Antiplasmin/Serpin F2 Protein, Cynomolgus (HEK293, His) is 464 a.a., with molecular weight of 60-70 kDa.

HY-P71297

	Serpin G1 Protein, Mouse (HEK293, His) serpin G1; Plasma protease C1 inhibitor; C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; serping1; C1nh	Mouse	HEK293
	Serpin G1 Protein, also called C1-inhibitor, regulates complement activation, blood coagulation, fibrinolysis, and kinin generation. It forms inactive complexes with C1r or C1s proteases, controlling C1 complex activation. Serpin G1 efficiently inhibits FXIIa and possibly chymotrypsin and kallikrein, and interacts with MASP1. Its inhibitory effects maintain pathway balance, preventing excessive activation and ensuring proper physiological function. Serpin G1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin G1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of Serpin G1 Protein, Mouse (HEK293, His) is 485 a.a., with molecular weight of 92-95 kDa.

HY-P71133

	Serpin E1 Protein, Mouse (N172S, R253G, HEK293, His) Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; serpin E1; Mr1; Pai1; Planh1;	Mouse	HEK293
	Serpin E1 Protein, a serine protease inhibitor, regulates TMPRSS7 and is a primary inhibitor for tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). It crucially down-regulates fibrinolysis, controlling blood clot degradation. As a PLAU inhibitor, Serpin E1 regulates cell adhesion and spreading, contributing to keratinocyte migration in cutaneous injury repair. Beyond protease inhibition, it regulates cell migration, influencing senescence, alveolar type 2 cells' senescence in the lung, cementogenic differentiation in periodontal ligament stem cells, and odontoblast differentiation in odontogenesis. Serpin E1 forms a heterodimer with TMPRSS7, interacts with proteins like VTN, PPP1CB, SORL1, LRP1, and PLAUR, emphasizing its multifaceted regulatory role. Serpin E1 Protein, Mouse (N172S, R253G, HEK293, His) is the recombinant mouse-derived Serpin E1 protein, expressed by HEK293 , with C-6*His labeled tag and N172S, R253G mutation. The total length of Serpin E1 Protein, Mouse (N172S, R253G, HEK293, His) is 380 a.a., with molecular weight of ~48.54 kDa.

HY-P71295

	*Alpha-2-Antiplasmin/Serpin* F2 Protein, Mouse (HEK293, His)** Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-plasmin inhibitor; Alpha-2-PI; serpin F2; serpinf2	Mouse	HEK293
	Alpha-2-Antiplasmin/Serpin F2 Protein, a serine protease inhibitor, targets plasmin and trypsin, also inhibiting matriptase-3/TMPRSS7 and chymotrypsin. It forms a heterodimer with TMPRSS7, enhancing its protease inhibiting activity. Alpha-2-Antiplasmin/Serpin F2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Alpha-2-Antiplasmin/Serpin F2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Alpha-2-Antiplasmin/Serpin F2 Protein, Mouse (HEK293, His) is 464 a.a., with molecular weight of 70-85 kDa.

HY-P7270

	Neuroserpin Protein, Human (CHO) rHuNeuroserpin; Peptidase inhibitor 12; serpin I1; serpinI1	Human	CHO
	Neuroserpin Protein, Human (CHO) is a member of the serpin family of serine protease inhibitors, playing an important role in synaptic plasticity and memory formation in the hippocampus.

HY-P73657

	Serpin A6 Protein, Mouse (HEK293, His) Corticosteroid-binding globulin; CBG; Transcortin; serpinA6	Mouse	HEK293
	Serpin A6 Protein serves as the primary transport protein for glucocorticoids and progestins in the blood of nearly all vertebrate species. Serpin A6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A6 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A6 Protein, Mouse (HEK293, His) is 375 a.a., with molecular weight of 50-60 kDa.

HY-P73658

	Serpin A6 Protein, Human (HEK293, His) Corticosteroid-binding globulin; CBG; Transcortin; serpinA6	Human	HEK293
	Serpin A6 Protein functions as a vital transport protein, facilitating the transport of glucocorticoids and progestins in the bloodstream across various vertebrate species. Serpin A6 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A6 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin A6 Protein, Human (HEK293, His) is 383 a.a., with molecular weight of 55-60 kDa.

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